749886-87-1
Chemical Structure
JSH-23
- CAS No.: 749886-87-1
- Formula:C16H20N2
- Molecular Weight:240.34
IUPAC Name: 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine
InChIKey: YMFNPBSZFWXMAD-UHFFFAOYSA-N
SMILES: NC1=CC(C)=CC=C1NCCCC2=CC=CC=C2
Biological Activity: JSH-23 is an NF-κB inhibitor which inhibits NF-κB transcriptional activity with an IC50 of 7.1 μM in lipopolysaccharide (LPS)-stimulated macrophages RAW 264.7. JSH-23 inhibits nuclear translocation of NF-κB p65 without affecting IκBα degradation[1].
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JSH-23 | 98.02% | JSH-23 is an NF-κB inhibitor which inhibits NF-κB transcriptional activity with an IC50 of 7.1 μM in lipopolysaccharide (LPS)-stimulated macrophages RAW 264.7. JSH-23 inhibits nuclear translocation of NF-κB p65 without affecting IκBα degradation. | ||||||||||||||||||||
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JSH-23 (Standard) | ≥98% | JSH-23 (Standard) is the analytical standard of JSH-23. This product is intended for research and analytical applications. JSH-23 is an NF-κB inhibitor which inhibits NF-κB transcriptional activity with an IC50 of 7.1 μM in lipopolysaccharide (LPS)-stimulated macrophages RAW 264.7. JSH-23 inhibits nuclear translocation of NF-κB p65 without affecting IκBα degradation. | ||||||||||||||||||||
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Keywords