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Brequinar sodium

(Synonyms: DuP785 sodium; NSC 368390 sodium)
34 Cited Publications
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Based on 34 publication(s) in Google Scholar

Brequinar (sodium) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

  • Purity: 99.22%
  • CAS No.: 96201-88-6
  • Formula: C23H14F2NNaO2
  • Molecular Weight:397.35
  • Storage:

    4°C, sealed storage, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • Brequinar sodium Chemical Structure
    Brequinar sodium Chemical Structure
  • Experimental Validation Results for Brequinar sodium
  • Experimental Validation Results for Brequinar sodium
  • Experimental Validation Results for Brequinar sodium
  • Experimental Validation Results for Brequinar sodium
  • Experimental Validation Results for Brequinar sodium
CAS No.: 96201-88-6
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Publications Citing Use of MedChemExpress (MCE) Brequinar sodium

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Microbiological AssayIn Vivo Efficacy StudyHistological Imaging/StainingBio/Physico-chemical Assay
  • Bio/Physico-chemical Assay
  • Microbiological Assay
  • In Vivo Efficacy Study
  • In Vivo Efficacy Study
  • Histological Imaging/Staining
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  • Brequinar sodium Chemical Structure
    Brequinar sodium Chemical Structure
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    Brequinar sodium purchased from MedChemExpress. Usage Cited in: Nature. 2024 Feb;626(7998):411-418. [Abstract]

    Customer Validation
     Mitochondrial lipid peroxidation assessment of HT1080 treated with RSL3 (0.5 μM) and BQR (Brequinar 200 μM) for 2 h after pretreatment of 7-DHC (25 μM) and Fer-1 for 24 h.

  • 1/16

    Brequinar sodium purchased from MedChemExpress. Usage Cited in: Nature. 2022 Apr;604(7904):134-140. [Abstract]

    Customer Validation
     Anti-SARS2 activity of Brequinar (0-10 μM, 1 h pretreatment and infected for 40-48 h).

  • 1/16

    Brequinar sodium purchased from MedChemExpress. Usage Cited in: Nature. 2022 Apr;604(7904):134-140. [Abstract]

    Customer Validation
     Lungs analyzed for viral titer by plaque assay. Wild type Balb/C mice were treated with Brequinar (IP) and/or molnupiravir (EIDD-2801) (PO) daily at the indicated concentrations starting 24 h after infection. Mice (N = 5 mice per group) were intranasally inoculated with 1×10^5 PFU/mouse of SARS-CoV-2/B.1.351.

  • 1/16

    Brequinar sodium purchased from MedChemExpress. Usage Cited in: Nature. 2022 Apr;604(7904):134-140. [Abstract]

    Customer Validation
     Lungs quantified for interstitial inflammation. Wild type Balb/C mice were treated with Brequinar (IP) and/or molnupiravir (EIDD-2801) (PO) daily at the indicated concentrations starting 24 h after infection. Mice (N = 5 mice per group) were intranasally inoculated with 1×10^5 PFU/mouse of SARS-CoV-2/B.1.351.

  • 1/16

    Brequinar sodium purchased from MedChemExpress. Usage Cited in: Nature. 2022 Apr;604(7904):134-140. [Abstract]

    Customer Validation
     Lungs fixed in 4% PFA for H&E staining (Scale bar = 200 μm). Wild type Balb/C mice were treated with Brequinar (IP) and/or molnupiravir (EIDD-2801) (PO) daily at the indicated concentrations starting 24 h after infection. Mice (N = 5 mice per group) were intranasally inoculated with 1×10^5 PFU/mouse of SARS-CoV-2/B.1.351.

  • Brequinar sodium