11 Results for "

basophilic leukemia

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "basophilic leukemia" in MCE Product Catalog:

Cat. No.: HY-P1640
CAS No.: 130154-64-2
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

(Trp63,Trp64)​-​C3a(63-77) is a C3a synthetic analogue peptide, which exhibits Ca 2+ stimulating efficacy in human neutrophils and hC3aR or mC3aR expressing RBL-2H3 cells with EC50 of 9.5, 2.0 and 0.8 nM, respectively .
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Cat. No.: HY-N8426
CAS No.: 79004-25-4
Synonyms: Ellisinin A
4'-O-Methylnyasol is an inhibitor of β-hexosaminidase. 4'-O-Methylnyasol inhibits β-hexosaminidase release from rat basophilic leukemia-2H3 cells with an IC50 of 52.67 μM .
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Cat. No.: HY-N11725
CAS No.: 128129-56-6
Phlorofucofuroeckol A is a FcεRI inhibitor with low cytotoxicity toward basophilic leukemia cells. Phlorofucofuroeckol A suppresses binding activity between IgE and FcεRI receptor. Phlorofucofuroeckol A inhibits histamine release from basophilic leukemia cells stimulated by IgE/anti-IgE or calcium ionophore A23187 (HY-N6687). Phlorofucofuroeckol A inhibits β-hexosaminidase release from basophilic leukemia cells stimulated by IgE/DNP-BSA. Phlorofucofuroeckol A can be used for the research of allergy disease .
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Cat. No.: HY-106064A
CAS No.: 88851-62-1
Synonyms: U 60257B
Piriprost potassium (U 60257B) is an inhibitor of Glutathione-S-transferase and leukotriene biosynthesis inhibitor. Piriprost potassium inhibits the biosynthesis of leukotriene C/D without affecting cyclooxygenase-mediated arachidonic acid metabolites. Piriprost potassium increases the activity of alkaline phosphatase (ALP). Piriprost potassium antagonizes contractions induced by leukotriene C/D in vitro. Piriprost potassium is used in asthma research .
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Cat. No.: HY-N21841
CAS No.: 71106-25-7
Stypodiol is an orally active sesquiterpenoid that can be isolated from Stypopodium flabelliforme. Stypodiol exhibits anticancer, gastric mucosal protective, and weak antibacterial activities. Stypodiol is used in research related to colon adenocarcinoma, neuroblastoma, basophilic leukemia, macrophage carcinoma, and gastric mucosal injury .
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Cat. No.: HY-180363
CAS No.: 120164-49-0
E 6080 is an orally active and selective 5-lipoxygenase (5-LOX) inhibitor with an IC50 of 0.2 μM in rat basophilic leukemia cell. E 6080 shows potent inhibitory effects on the release of leukotrienes. E 6080 inhibits the bronchospasm induced by antigen (ovalbumin) inhalation in sensitized conscious guinea pigs. E 6080 can be used for the study of asthma .
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Cat. No.: HY-N19857
CAS No.: 562070-88-6
Millettiasaponin A is an oleanane-type triterpenoid saponin found in the stems of Derris eriocarpa and roots of Millettia speciosa. Millettiasaponin A is 150 times sweeter than Sucrose (HY-B1779) at 1% concentration. Millettiasaponin A can be used in research on hypertension and obesity. .
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Cat. No.: HY-N19858
CAS No.: 562070-89-7
Millettiasaponin B is an oleanane-type triterpene saponin found in the roots of Millettia speciosa. Millettiasaponin B can be used in leukemia research .
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Cat. No.: HY-106064
CAS No.: 79672-88-1
Synonyms: U-60257
Piriprost (U-60257) is an inhibitor of Glutathione-S-transferase and leukotriene biosynthesis inhibitor. Piriprost inhibits the biosynthesis of leukotriene C/D without affecting cyclooxygenase-mediated arachidonic acid metabolites. Piriprost increases the activity of alkaline phosphatase (ALP). Piriprost antagonizes contractions induced by leukotriene C/D in vitro. Piriprost is used in asthma research .
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Cat. No.: HY-19014
CAS No.: 83677-24-1
Target:  

Lipoxygenase COX

Research Areas:  

Inflammation/Immunology

KME-4 is an orally active dual inhibitor of 5-lipoxygenase (5-lipoxygenase) and cyclooxygenase (cyclooxygenase). KME-4 inhibits 5-lipoxygenase in the cytosol of guinea pig polymorphonuclear leukocytes (PMNL) and cyclooxygenase in rabbit platelets, with IC50 values of 0.85 μM and 0.44 μM, respectively. KME-4 can be used in studies related to arachidonic acid metabolism, inflammatory responses, and arthritis .
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Cat. No.: HY-171831
CAS No.: 79494-05-6
Target:  

Endogenous Metabolite

Research Areas:  

Inflammation/Immunology

Leukotriene E3 is a cysteinyl leukotriene metabolite derived from 5,8,11-eicosatrienoic acid (HY-108398A). Leukotriene E3 acts as a smooth-muscle-contracting mediator. Leukotriene E3 can be used for the research of allergic reactions and asthma .
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