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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
bifunctional fusion protein
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "bifunctional fusion protein" in MCE Product Catalog:
Cat. No.: HY-P99480
CAS No.: 1918149-01-5
Synonyms: M7824; MSB0011359C
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Cat. No.: HY-P99944
CAS No.: 2891860-17-4
Synonyms: Retlirafusp alfa
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Cat. No.: HY-P99687
CAS No.: 2552814-07-8
Synonyms: AMG 256
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Cat. No.: HY-177767
CAS No.: 960294-74-0
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EY-CBS is a synthetic and rigid cross linker. EY-CBS reacts selectively with cysteines in a-helices, to stabilize the connecting helix. EY-CBS can be used for the study of the structural stability of protein polypeptides .
Cat. No.: HY-161162
CAS No.: 2387510-81-6
Synonyms: CFT-2139
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aTAG 2139 (CFT-2139) is a bifunctional tag-targeted PROTAC-class degrader that induces the degradation of the MTH1 aTAG fusion protein by recruiting cereblon, with a DC50 of 1.1 nM (in Jurkat T cells). aTAG 2139 is applicable to the research of CD19-positive cancers .
Cat. No.: HY-P991084
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Cat. No.: HY-W1124386
CAS No.: 1820756-74-8
Synonyms: SNAP-DBCO
Cat. No.: HY-E71769
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3-Oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase (EC 1.2.1.91) from Escherichia coli is a bifunctional fusion protein that also catalyses EC 3.3.2.12, oxepin-CoA hydrolase.
Cat. No.: HY-185051
OTX-2002 is an mRNA encoding two bifunctional fusion proteins (ZFBD-MQ1 and ZFBD-KRAB). OTX-2002 targets regulatory elements located within the MYC protection gene domain (IGD) and induces the methylation of DNA and histone, leading to the downregulation of MYC expression.
Cat. No.: HY-182964
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Cardiovascular Disease Neurological Disease Metabolic Disease Cancer
WY165 is a bifunctional molecule comprising TR79, an activator of the mitochondrial protease complex caseinolytic protease P (ClpP), linked to desthiobiotin. WY165 mediates selective degradation of monomeric streptavidin (mSA) and its fusion proteins localized to the mitochondrial matrix with a DC50 of 197 nM. WY165 restores mitochondrial morphology by reducing the level of mSA fused to short transmembrane protein 1 (mSA-STMP1) in cells overexpressing mSA-STMP1. WY165 can be used for research in cancer, neurodegenerative diseases, cardiovascular diseases, and metabolic diseases .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
