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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
cholecystokinin-B
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "cholecystokinin-B" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P2671
CAS No.: 39024-57-2
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Cat. No.: HY-U00360
CAS No.: 168161-71-5
Synonyms: (Rac)-Netazepide; (Rac)-YF 476; (Rac)-YM-220
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(Rac)-Sograzepide is an antagonist of cholecystokinin B (CCK-B) receptor, and has the potential of reducing the secretion of gastric acid.
Cat. No.: HY-123434
CAS No.: 181941-32-2
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PD-149164 is a potent agonist of cholecystokinin B (CCK-B) receptor, with IC50 values of 0.083 nM and 75 nM in binding assay to CCK-B and CCK-A .
Cat. No.: HY-P11540
CAS No.: 2923120-30-1
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Cat. No.: HY-U00360R
CAS No.: 168161-71-5
Synonyms: (Rac)-Netazepide (Standard); (Rac)-YF 476 (Standard); (Rac)-YM-220 (Standard)
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(Rac)-Sograzepide is an antagonist of cholecystokinin B (CCK-B) receptor, and has the potential of reducing the secretion of gastric acid.
Cat. No.: HY-125314
CAS No.: 159883-95-1
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AG-041R is a potent and selective CCK2 Receptor/Gastrin antagonist. AG-041R inhibits gastrin-evoked secretion of pancreastatin with an IC50 of 2.2 nM. AG-041R inhibits cell growth of Mastomys ECL carcinoid tumor cells .
Cat. No.: HY-125692
CAS No.: 154967-59-6
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L-740093 is a potent cholecystokinin-B receptor antagonist. L-740093 has excellent central nervous system (CNS) penetration .
Cat. No.: HY-169139
CAS No.: 137795-35-8
Synonyms: CR-2194
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Spiroglumide (CR-2194) is a selective cholecystokinin B (CCKB) receptor antagonist .
Cat. No.: HY-120862
CAS No.: 145878-31-5
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L 368935 is a cholecystokinin B receptor (CCKB receptor) antagonist. L 368935 is a brain-penetrant and centrally active compound .
Cat. No.: HY-120302
CAS No.: 149027-97-4
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PD 140376 is a potent antagonist for the cholecystokininB/gastrin receptor, with Ki values of 0.18 nM and 0.21 nM in guinea-pig cortex and gastric gland membranes, respectively .
Cat. No.: HY-114966
CAS No.: 197012-43-4
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RP73870 is an orally active gastrin/cholecystokinin-B receptor antagonist. RP73870 inhibits basal gastric acid secretion in the rat. RP73870 has potent anti-ulcer activity .
Cat. No.: HY-A0261A
CAS No.: 57448-84-7
Synonyms: ICI-50123 meglumine
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Pentagastrin (ICI-50123) meglumine is a potent, selective Cholecystokinin B (CCKB) receptor agonist with an EC50 value of 11 nM. Pentagastrin meglumine enhances gastric mucosal defense mechanisms against acid and protects the gastric mucosa from experimental injury .
Cat. No.: HY-117839
CAS No.: 134557-41-8
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PD-135666 is a dipeptide inhibitor of cholecystokinin B (CCK B) receptors, binding to CCK B receptors in mouse cerebral cortex with IC50 of 0.1 nM. Its enantiomer, PD-140548, preferentially binds to CCK A receptors with IC50 of 2.8 nM in rat pancreas. PD-135666 exhibits anxiolytic effects in animal models .
Cat. No.: HY-118665
CAS No.: 152885-49-9
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L-736380 is a high affinity CCK-B (cholecystokinin B receptor) receptor antagonist, with IC50 values of 0.054 nM and 400 nM for CCK-B and CCK-A, respectively. L-736380 dose-dependently inhibits gastric acid secretion in anesthetized rats (ID50, 0.064 mg/kg) and ex vivo binding of [125I]CCK-8S in BKTO mice brain membranes (ED50, 1.7 mg/kg) .
Cat. No.: HY-116260
CAS No.: 138562-23-9
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RP-69758 is a potent and selective non-peptide cholecystokinin-B (CCKB)/gastrin receptor antagonist. RP-69758 exhibits >200-fold selectivity for CCKB over CCKA receptors. RP-69758 antagonizes CCK-8-induced neuronal firing in rat hippocampal slices. RP-69758 inhibits Pentagastrin (HY-A0261)-induced gastric acid secretion in the rat. RP-69758 can be used for neurological disorders and gastrointestinal disease research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
