L-736380
L-736380 is a high affinity CCK-B (cholecystokinin B receptor) receptor antagonist, with IC50 values of 0.054 nM and 400 nM for CCK-B and CCK-A, respectively. L-736380 dose-dependently inhibits gastric acid secretion in anesthetized rats (ID50, 0.064 mg/kg) and ex vivo binding of [125I]CCK-8S in BKTO mice brain membranes (ED50, 1.7 mg/kg).
For research use only. We do not sell to patients.
- CAS No.: 152885-49-9
- Formula: C25H29N9O2
- Molecular Weight:487.56
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 152885-49-9
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Molecular Weight 487.56
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Formula C25H29N9O2
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SMILES
O=C(N[C@H]1C(N(C2=CC=CC=C2C(C3CCCCC3)=N1)C)=O)NC4=CC=CC(N(C5=NNN=N5)C)=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
L-736380 Related Classifications
HY-118665 Related Classifications
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