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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
cytosolic Hsp90
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "cytosolic Hsp90" in MCE Product Catalog:
4
4 Cited Publications
Cat. No.: HY-P72238
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Hsp90AA1; Heat Shock 86 KDa; Prev. HspC1; FLJ31884; Prev. HspCA; Hsp90A; Prev. HspCAL4; Hsp 86; Hsp90N; Hsp86; Hsp89; LAP-2; Hsp90; Heat Shock Protein 90kDa Alpha Family Class A Member 1; Heat Shock Protein 90kDa Alpha (cytosolic), Class A Member 1; Heat
Species:
Human
Source:
E. coli
YK5 is a potent and selective Hsp70 inhibitor. YK5 selectively and tightly binds to the cytosolic Hsp70s in cancer cells. YK5 has biological activity partly by interfering with the formation of active oncogenic Hsp70/Hsp90/client protein complexes .
Cat. No.: HY-155064
CAS No.: 3031102-92-5
Target:
Research Areas:
TRAP1-IN-2 is a TRAP1-selective inhibitor, with a Kd value of 0.04 μM against human TRAP1. TRAP1-IN-2 exhibits more than 250-fold selectivity for Grp94 and shows no detectable affinity for cytosolic Hsp90α/β. TRAP1-IN-2 selectively induces the degradation of TRAP1 client proteins by inhibiting its ATPase activity, without triggering the heat shock response or affecting cytosolic Hsp90 client proteins. TRAP1-IN-2 suppresses oxidative phosphorylation, shifts cellular metabolism toward glycolysis, disrupts the stability of the TRAP1 tetramer and the mitochondrial membrane potential. TRAP1-IN-2 can be used in studies related to prostate cancer, cervical cancer, and ovarian cancer .
Cat. No.: HY-182302
CAS No.: 1695550-43-6
Target:
Research Areas:
SMTIN-P01 is a TRAP1 inhibitor that is selective for cytosolic Hsp90 and accumulates in mitochondria. SMTIN-P01 binds to the ATP-binding site of TRAP1 as an ATP mimic, thereby inhibiting ATPase and foldase activities. SMTIN-P01 induces mitochondrial membrane depolarization and proteolytic degradation in cancer cells. SMTIN-P01 exhibits significant cytotoxicity, but shows extremely low toxicity to primary mouse hepatocytes, and does not interfere with SIRT3-related functions or the levels of cytosolic Hsp90 substrates. SMTIN-P01 has important application value in cancer-related research .
Cat. No.: HY-P85596
Synonyms: Hsp90AB1; 90 kda heat shock protein beta Hsp90 beta; D6S182; FLJ26984; Heat shock 84 kDa; Heat shock 90kD protein 1, beta; Heat shock 90kDa protein 1 beta; Heat shock protein 90kDa alpha; cytosolic; class B member 1; Heat shock protein beta; Heat shock protein Hsp 90 beta; Heat shock protein Hsp 90-beta; HS90B_HUMAN; Hsp 84; Hsp 90; Hsp 90 b; Hsp 90b; Hsp84; Hsp90 BETA; Hsp90ab1; Hsp90B; HspC2; HspCB.
Cat. No.: HY-P703570
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Hsp90AB1; Hsp84; Prev. HspC2; Heat Shock 90kDa Protein 1, Beta; Prev. HspCB; Heat Shock Protein 90 KDa; Heat Shock Protein 90kDa Alpha (cytosolic), Class B Member 1; Hsp90AB1 Protein; Heat Shock Protein Family C Member 3; Hsp90-Beta; Heat Shock 90kD Prote
Species:
Human
Source:
E. coli
Cat. No.: HY-P704104
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Hsp90AA1; Heat Shock 86 KDa; Prev. HspC1; FLJ31884; Prev. HspCA; Hsp90A; Prev. HspCAL4; Hsp 86; Hsp90N; Hsp86; Hsp89; LAP-2; Hsp90; Heat Shock Protein 90kDa Alpha Family Class A Member 1; Heat Shock Protein 90kDa Alpha (cytosolic), Class A Member 1; Heat
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P72051
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Hsp90AA1; Heat Shock 86 KDa; Prev. HspC1; FLJ31884; Prev. HspCA; Hsp90A; Prev. HspCAL4; Hsp 86; Hsp90N; Hsp86; Hsp89; LAP-2; Hsp90; Heat Shock Protein 90kDa Alpha Family Class A Member 1; Heat Shock Protein 90kDa Alpha (cytosolic), Class A Member 1; Heat
Species:
Others
Source:
Sf9 insect cells
Cat. No.: HY-P703083
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Hsp90AA1; Heat Shock 86 KDa; Prev. HspC1; FLJ31884; Prev. HspCA; Hsp90A; Prev. HspCAL4; Hsp 86; Hsp90N; Hsp86; Hsp89; LAP-2; Hsp90; Heat Shock Protein 90kDa Alpha Family Class A Member 1; Heat Shock Protein 90kDa Alpha (cytosolic), Class A Member 1; Heat Shock 90kD Protein 1, Alpha-Like 4; Epididymis Secretory Sperm Binding Protein Li 65p; Heat Shock 90kD Protein, Alpha-Like 4; Epididymis Luminal Secretory Protein 52; Hsp90AA1 Protein; Lipopolysaccharide-Associated Protein 2; HspCAL1; Heat Shock Protein Family C Member 1; Hsp89A; Heat Shock 90kDa Protein 1, Alpha; Hsp103; Renal Carcinoma Antigen NY-REN-38; EL52; Heat Shock 90kD Protein 1, Alpha; HspN; Heat Shock Protein Hsp 90-Alpha; LAP2; LPS-Associated Protein 2; Heat Shock Protein 90 Alpha Family Class A Member 1; HEL-S-65p
Species:
Human
Source:
E. coli
Cat. No.: HY-P706229
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Hsp90AA1; Heat Shock 86 KDa; Prev. HspC1; FLJ31884; Prev. HspCA; Hsp90A; Prev. HspCAL4; Hsp 86; Hsp90N; Hsp86; Hsp89; LAP-2; Hsp90; Heat Shock Protein 90kDa Alpha Family Class A Member 1; Heat Shock Protein 90kDa Alpha (cytosolic), Class A Member 1; Heat Shock 90kD Protein 1, Alpha-Like 4; Epididymis Secretory Sperm Binding Protein Li 65p; Heat Shock 90kD Protein, Alpha-Like 4; Epididymis Luminal Secretory Protein 52; Hsp90AA1 Protein; Lipopolysaccharide-Associated Protein 2; HspCAL1; Heat Shock Protein Family C Member 1; Hsp89A; Heat Shock 90kDa Protein 1, Alpha; Hsp103; Renal Carcinoma Antigen NY-REN-38; EL52; Heat Shock 90kD Protein 1, Alpha; HspN; Heat Shock Protein Hsp 90-Alpha; LAP2; LPS-Associated Protein 2; Heat Shock Protein 90 Alpha Family Class A Member 1; HEL-S-65p
Species:
Human
Source:
E. coli
Cat. No.: HY-P703571
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Hsp90AB1; Hsp84; Prev. HspC2; Heat Shock 90kDa Protein 1, Beta; Prev. HspCB; Heat Shock Protein 90 KDa; Heat Shock Protein 90kDa Alpha (cytosolic), Class B Member 1; Hsp90AB1 Protein; Heat Shock Protein Family C Member 3; Hsp90-Beta; Heat Shock 90kD Prote
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P703572
Synonyms: Hsp90AB1; Hsp84; Prev. HspC2; Heat Shock 90kDa Protein 1, Beta; Prev. HspCB; Heat Shock Protein 90 KDa; Heat Shock Protein 90kDa Alpha (cytosolic), Class B Member 1; Hsp90AB1 Protein; Heat Shock Protein Family C Member 3; Hsp90-Beta; Heat Shock 90kD Prote
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
