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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
61 Results for "
diastereomer
" in MedChemExpress (MCE) Product Catalog:
Products (61)
61 Results for "diastereomer" in MCE Product Catalog:
7
7 Publications Verification
Cat. No.: HY-134818
Purity: 99.80%
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ML-SI1, a racemic mixture of diastereomers, is a TRPML inhibitor with an IC50 value of 15 μM for TRPML1 .
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1 Cited Publications
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(1R,2R)-2-PCCA hydrochloride is a diastereomer of 2-PCCA, and acts as a potent GPR88 receptor agonist, with an EC50 of 3 nM in cell-free assay, and 603 nM in cell assay.
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1 Cited Publications
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(R)-mchm5U is a diastereomer of (S)-mchm5U (HY-153100A) .
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dTAGV-1-NEG is an inactive FKBP12 F36V PROTAC degrader, the diastereomer of dTAGV-1 (HY-145514D), and a heterobifunctional negative control molecule. dTAGV-1-NEG does not degrade any protein .
Cat. No.: HY-W008315
CAS No.: 28954-12-3
Synonyms: H-allo-Thr-OH
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Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields
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Cat. No.: HY-172825
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KL4‑219A is a more durable MYC degrader derived from structural optimization of KL2‑236, with its inactive diastereomer being KL4‑219B. KL4‑219A induces destabilization and degradation of MYC protein in a proteasome-dependent manner. KL4‑219A is applicable to the research of pancreatic cancer .
Cat. No.: HY-147099
Purity: 97.8%
dTAG-47-NEG is an inactive bifunctional negative control PROTAC and also the diastereomer of dTAGV-1 (HY-145514D). dTAG-47-NEG does not reduce the level of BCL11A-FKBP12 F36V, nor does it induce the degradation of BCL11A-FKBP12 F36V, proteins tagged with FKBP12 F36V, wild-type FKBP12, FKBP12 F36V-KRAS G12V or FKBP12 F36V-EWS/FLI. dTAG-47-NEG exerts no antiproliferative effect in cancer cells .
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LLY-284 is the diastereomer of LLY-283 with much less active. LLY-283 is a potent inhibitor of PRMT5. LLY-284 has the potential for the research of cancer diseases .
Synonyms: 1β,25-Dihydroxyvitamin-D3; 1-Epicalcitriol
Impurity B of Calcitriol is a diastereomer of 1α,25-dihydroxyvitamin D3 that interferes with accurate Calcitriol quantification .
Cat. No.: HY-W777284
CAS No.: 1217532-71-2
Cat. No.: HY-154959A
Purity: 98.90%
(9R,12aR)-AZD4747 is a diastereomer of AZD4747 (HY-154959). AZD4747 is a selective mutant GTPase KRAS G12C inhibitor with blood-brain barrier permeability. AZD4747 has the potential to study cancer .
Cat. No.: HY-W008315R
CAS No.: 28954-12-3
Synonyms: H-allo-Thr-OH (Standard)
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Cat. No.: HY-W653769
CAS No.: 1217633-23-2
Cat. No.: HY-155356A
CAS No.: 3053689-54-3
YN14 mixture of diastereomers is a diastereomer mixture of YN14 (HY-155356). YN14 is a KRAS G12C PROTAC degrader that recruits E3 ubiquitin ligase to induce the polyubiquitination and proteasomal degradation of KRAS G12C. YN14 induces tumor cell apoptosis, cell cycle arrest, and cell migration inhibition. YN14 exhibits in vivo antitumor proliferative activity in tumor cell xenograft nude mice. YN14 can be used in cancer-related research .
Cat. No.: HY-W654395
Synonyms: Methyl jasmonate-d5 (2,4,4-d3; acetyl-2,2-d2)(mixture of diastereomers)
Cat. No.: HY-145514B
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dTAGV-1-NEG TFA is an inactive FKBP12 F36V PROTAC degrader, the diastereomer of dTAGV-1 (HY-145514D), and a heterobifunctional negative control molecule. dTAGV-1-NEG TFA does not degrade any protein .
Cat. No.: HY-W144704B
CAS No.: 189302-44-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
