19 Results for "

dihydroartemisinin

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "dihydroartemisinin" in MCE Product Catalog:

45
45 Publications Verification
Cat. No.: HY-N0176
CAS No.: 71939-50-9
Synonyms: Dihydroqinghaosu; β-dihydroartemisinin; Artenimol
Dihydroartemisinin is an orally active metabolite of rtemisinin (HY-B0094) and antimalarial agent. Dihydroartemisinin induces Autophagy by inhibiting NF-κB activation. Dihydroartemisinin promotes ROS accumulation. Dihydroartemisinin exhibits anticancer activity in esophageal cancer cells. Dihydroartemisinin shows schistosomicidal activity against juvenile and adult worms of Schistosoma japonicum, reduces worm burden, and displays antiparasitic activity. Dihydroartemisinin can be used in research related to multiple myeloma, promyelocytic leukemia, esophageal cancer, and Schistosoma japonicum infection .
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18
18 Cited Publications
Cat. No.: HY-143218
CAS No.: 1245606-71-6
Purity:  98.05%
Synonyms: Tetraphenylethene maleimide
TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasites Plasmodium falciparum .
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3
3 Cited Publications
Cat. No.: HY-N0402
CAS No.: 71963-77-4
Synonyms: Dihydroqinghaosu methyl ether; dihydroartemisinin methyl ether; SM224
Artemether is an anti-malarial compound that targets drug-resistant strains of falciparum malaria .
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Cat. No.: HY-N0176R
CAS No.: 71939-50-9
Synonyms: Dihydroqinghaosu (Standard); β-dihydroartemisinin (Standard); Artenimol (Standard)
Dihydroartemisinin (Standard) (Dihydroqinghaosu (Standard)) is the analytical standard of Dihydroartemisinin (HY-N0176). This product is intended for research and analytical applications. Dihydroartemisinin is an orally active metabolite of rtemisinin (HY-B0094) and antimalarial agent. Dihydroartemisinin induces Autophagy by inhibiting NF-κB activation. Dihydroartemisinin promotes ROS accumulation. Dihydroartemisinin exhibits anticancer activity in esophageal cancer cells. Dihydroartemisinin shows schistosomicidal activity against juvenile and adult worms of Schistosoma japonicum, reduces worm burden, and displays antiparasitic activity. Dihydroartemisinin can be used in research related to multiple myeloma, promyelocytic leukemia, esophageal cancer, and Schistosoma japonicum infection .
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Cat. No.: HY-12912
CAS No.: 1513879-19-0
Purity:  99.42%
Target:  

PI4K Parasite

Research Areas:  

Infection

KDU691, an imidazopyrazine with potent anti-parasitic activity against blood stage schizonts, gametocytes and liver stages, is a Plasmodium PI4K inhibitor. KDU691 selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites .
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Cat. No.: HY-W129233
CAS No.: 131175-87-6
Synonyms: dihydroartemisinin (α,β mixture)
Research Areas:  

Infection Cancer

Dihydroartemisinin (mixture of α and β isomers) is an anti-malaria and anticancer agent, as well as an active metabolite of artemisinin and its derivatives. Dihydroartemisinin exerts anticancer effects through various molecular mechanisms, such as inhibiting proliferation, inducing apoptosis, inhibiting tumor metastasis and angiogenesis, promoting immune function, inducing autophagy and endoplasmic reticulum stress .
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Cat. No.: HY-N0402S
CAS No.: 93787-85-0
Synonyms: Dihydroqinghaosu methyl ether-d3; dihydroartemisinin methyl ether-d3; SM224-d3
Artemether-d3 is the deuterium labeled Artemether. Artemether is an antimalarial for the treatment of resistant strains of falciparum malaria.
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Cat. No.: HY-DY1024
CAS No.: 1245606-71-6
TPE-MI (Tetraphenylethene maleimide) (solution) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasitesPlasmodium falciparum .
Solvent and concentration: DMSO: 10 mM
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Cat. No.: HY-W653724
CAS No.: 1093625-96-7
Target:  

Drug Intermediate

Research Areas:  

Others

Dihydroartemisinin diketo aldehyde is an Artemether (HY-N0402) impurity.
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Cat. No.: HY-N0176S
CAS No.: 176774-98-4
Synonyms: Dihydroqinghaosu-d3; β-dihydroartemisinin-d3; Artenimol-d3
Dihydroartemisinin-d3 (Dihydroqinghaosu-d3) is the d3-labeled Dihydroartemisinin (HY-N0176). Dihydroartemisinin is an orally active metabolite of rtemisinin (HY-B0094) and antimalarial agent. Dihydroartemisinin induces Autophagy by inhibiting NF-κB activation. Dihydroartemisinin promotes ROS accumulation. Dihydroartemisinin exhibits anticancer activity in esophageal cancer cells. Dihydroartemisinin shows schistosomicidal activity against juvenile and adult worms of Schistosoma japonicum, reduces worm burden, and displays antiparasitic activity. Dihydroartemisinin can be used in research related to multiple myeloma, promyelocytic leukemia, esophageal cancer, and Schistosoma japonicum infection .
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Cat. No.: HY-W754303
Synonyms: Dihydroqinghaosu-13C,d5; β-dihydroartemisinin-13C,d5; Artenimol-13C,d5
Dihydroartemisinin- 13C,d5 (Dihydroqinghaosu- 13C,d5) is the deuterium labeled and 13C-labeled Dihydroartemisinin (HY-N0176). Dihydroartemisinin is a potent anti-malaria agent.
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Cat. No.: HY-N0176S3
Synonyms: Dihydroqinghaosu-d5; β-dihydroartemisinin-d5; Artenimol-d5
Dihydroartemisinin-d5 (Dihydroqinghaosu-d5) is the d5-labeled Dihydroartemisinin (HY-N0176). Dihydroartemisinin is an orally active metabolite of rtemisinin (HY-B0094) and antimalarial agent. Dihydroartemisinin induces Autophagy by inhibiting NF-κB activation. Dihydroartemisinin promotes ROS accumulation. Dihydroartemisinin exhibits anticancer activity in esophageal cancer cells. Dihydroartemisinin shows schistosomicidal activity against juvenile and adult worms of Schistosoma japonicum, reduces worm burden, and displays antiparasitic activity. Dihydroartemisinin can be used in research related to multiple myeloma, promyelocytic leukemia, esophageal cancer, and Schistosoma japonicum infection .
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Cat. No.: HY-118865
CAS No.: 911061-10-4
Target:  

Parasite

Research Areas:  

Infection

Piperaquine tetraphosphate is a potent antimalaria agent. Piperaquine tetraphosphate shows inhibition for chloroquine-sensitive and the chloroquine-resistant isolates. Piperaquine tetraphosphate in combination with dihydroartemisinin has the potential for the research of chloroquine-resistant malaria .
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Cat. No.: HY-N0402R
CAS No.: 71963-77-4
Synonyms: Dihydroqinghaosu methyl ether (Standard); dihydroartemisinin methyl ether (Standard); SM224 (Standard)
Artemether (Standard) is the analytical standard of Artemether. This product is intended for research and analytical applications. Artemether is an anti-malarial compound that targets drug-resistant strains of falciparum malaria .
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Cat. No.: HY-134563
CAS No.: 767287-99-0
Target:  

Caspase Apoptosis

Research Areas:  

Cancer

Z-Asp(OMe)-Gln-Met-Asp(OMe)-FMK is an inhibitor for caspase-3, and inhibits Dihydroartemisinin (HY-N0176) and Dictamnine (HY-N0849) co-induced apoptosis .
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Cat. No.: HY-N0176S6
CAS No.: 252043-36-0
Synonyms: Dihydroqinghaosu-d; β-dihydroartemisinin-d; Artenimol-d
Dihydroartemisinin-d (Dihydroqinghaosu-d) is the d-labeled Dihydroartemisinin (HY-N0176). Dihydroartemisinin is an orally active metabolite of rtemisinin (HY-B0094) and antimalarial agent. Dihydroartemisinin induces Autophagy by inhibiting NF-κB activation. Dihydroartemisinin promotes ROS accumulation. Dihydroartemisinin exhibits anticancer activity in esophageal cancer cells. Dihydroartemisinin shows schistosomicidal activity against juvenile and adult worms of Schistosoma japonicum, reduces worm burden, and displays antiparasitic activity. Dihydroartemisinin can be used in research related to multiple myeloma, promyelocytic leukemia, esophageal cancer, and Schistosoma japonicum infection .
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Cat. No.: HY-160962
CAS No.: 1331880-08-0
Target:  

Caspase Apoptosis

Research Areas:  

Cancer

SM1044 is a dihydroartemisinin (DHA) dimer. SM1044 activates caspase, induces apooptosis in RL95-2 and KLE cells. SM1044 inhibits proliferations of cancer cells RL95-2, KLE, HEC-50, HEC-1-A, HEC-1-B, AN3CA, with IC50 < 3.6 μM . SM1044 inhbits tumor growth in RL95-2 xenograft mouse model .
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Cat. No.: HY-W768856
Synonyms: Dihydroqinghaosu methyl ether-13C,d3; dihydroartemisinin methyl ether-13C,d3; SM224-13C,d3
Artemether- 13C,d3 (Dihydroqinghaosu methyl ether- 13C,d3) is the deuterium and 13C-labeled Artemether (HY-N0402). Artemether is an anti-malarial compound that targets drug-resistant strains of falciparum malaria .
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Cat. No.: HY-183574
Target:  

Parasite

Research Areas:  

Infection

Antimalarial agent 62 is an orally active imidazopyridine-6-carboxamide antimalarial agent with a high resistance barrier. Antimalarial agent 62 kills trophozoite-stage Plasmodium ring forms, effectively clears dihydroartemisinin-induced dormant Plasmodium ring forms, and eliminates parasitemia in mice infected with Plasmodium yoelii. In AReBaR resistance omics screening, Antimalarial agent 62 is not affected by different target- and efflux-mediated resistance mutations and can withstand resistance selection. Antimalarial agent 62 has been applied to studies of malaria-related mechanisms .
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