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dihydroartemisinin

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (7) Autophagy (7) Caspase (2) Drug Intermediate (1) Drug Metabolite (2) Huntingtin (2) Isotope-Labeled Compounds (5) NF-κB (6) Parasite (16) PI4K (1) Reactive Oxygen Species (ROS) (2) Reference Standards (2)
By Research Areas:	Cancer (13) Infection (15) Inflammation/Immunology (5) Metabolic Disease (2) Neurological Disease (4)

Inhibitors & Agonists

Fluorescent Dyes

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0176

*Dihydroartemisinin* 40+ Cited Publications Dihydroqinghaosu; β-dihydroartemisinin; Artenimol	Parasite NF-κB Autophagy Reactive Oxygen Species (ROS) Drug Metabolite	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Dihydroartemisinin is an orally active metabolite of rtemisinin (HY-B0094) and antimalarial agent. Dihydroartemisinin induces Autophagy by inhibiting NF-κB activation. Dihydroartemisinin promotes ROS accumulation. Dihydroartemisinin exhibits anticancer activity in esophageal cancer cells. Dihydroartemisinin shows schistosomicidal activity against juvenile and adult worms of Schistosoma japonicum, reduces worm burden, and displays antiparasitic activity. Dihydroartemisinin can be used in research related to multiple myeloma, promyelocytic leukemia, esophageal cancer, and Schistosoma japonicum infection .

HY-N0402

Artemether 3 Publications Verification Dihydroqinghaosu methyl ether; dihydroartemisinin methyl ether; SM224	Parasite	Infection Inflammation/Immunology Cancer
Artemether is an anti-malarial compound that targets drug-resistant strains of falciparum malaria .

HY-143218

TPE-MI 10+ Cited Publications Tetraphenylethene maleimide	Huntingtin Parasite	Infection Neurological Disease
TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasites Plasmodium falciparum .

HY-N0176R

Dihydroartemisinin (Standard) Dihydroqinghaosu (Standard); β-dihydroartemisinin (Standard); Artenimol (Standard)	Reference Standards Parasite NF-κB Autophagy Apoptosis	Infection Cancer
Dihydroartemisinin (Standard) is the analytical standard of Dihydroartemisinin. This product is intended for research and analytical applications. Dihydroartemisinin is a potent anti-malaria agent.

HY-12912

KDU691	PI4K Parasite	Infection
KDU691, an imidazopyrazine with potent anti-parasitic activity against blood stage schizonts, gametocytes and liver stages, is a Plasmodium PI4K inhibitor. KDU691 selectively inhibits dihydroartemisinin-pretreated Plasmodium falciparum ring-stage parasites .

HY-W129233

Dihydroartemisinin (mixture of α and β isomers) dihydroartemisinin (α,β mixture)	Parasite Autophagy Apoptosis	Infection Cancer
Dihydroartemisinin (mixture of α and β isomers) is an anti-malaria and anticancer agent, as well as an active metabolite of artemisinin and its derivatives. Dihydroartemisinin exerts anticancer effects through various molecular mechanisms, such as inhibiting proliferation, inducing apoptosis, inhibiting tumor metastasis and angiogenesis, promoting immune function, inducing autophagy and endoplasmic reticulum stress .

HY-N0402S

Artemether-d3 Dihydroqinghaosu methyl ether-d₃; dihydroartemisinin methyl ether-d₃; SM224-d₃	Isotope-Labeled Compounds Parasite	Infection Cancer
Artemether-d₃ is the deuterium labeled Artemether. Artemether is an antimalarial for the treatment of resistant strains of falciparum malaria.

HY-DY1024

TPE-MI (solution)	Huntingtin Parasite	Infection Neurological Disease
TPE-MI (Tetraphenylethene maleimide) (solution) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasitesPlasmodium falciparum . Solvent and concentration: DMSO: 10 mM

HY-W653724

Dihydroartemisinin diketo aldehyde	Drug Intermediate	Others
Dihydroartemisinin diketo aldehyde is an Artemether (HY-N0402) impurity.

HY-N0176S

Dihydroartemisinin-d3 Dihydroqinghaosu-d₃; β-dihydroartemisinin-d₃; Artenimol-d₃	Parasite NF-κB Autophagy Apoptosis	Infection Cancer
Dihydroartemisinin-d₃ is the deuterium labeled Dihydroartemisinin. Dihydroartemisinin is a potent anti-malaria agent.

HY-W754303

Dihydroartemisinin-13C,d5 Dihydroqinghaosu-¹³C,d₅; β-dihydroartemisinin-¹³C,d₅; Artenimol-¹³C,d₅	Isotope-Labeled Compounds Apoptosis Autophagy Parasite NF-κB	Cancer
Dihydroartemisinin- ¹³C,d₅ (Dihydroqinghaosu- ¹³C,d₅) is the deuterium labeled and ¹³C-labeled Dihydroartemisinin (HY-N0176). Dihydroartemisinin is a potent anti-malaria agent.

HY-N0176S3

Dihydroartemisinin-d5 Dihydroqinghaosu-d5; β-dihydroartemisinin-d5; Artenimol-d5	Apoptosis Parasite Autophagy NF-κB Isotope-Labeled Compounds	Infection Cancer
Dihydroartemisinin-d₅ is deuterated labeled Dihydroartemisinin (HY-N0176). Dihydroartemisinin is a potent anti-malaria agent.

HY-118865

Piperaquine tetraphosphate	Parasite	Infection
Piperaquine tetraphosphate is a potent antimalaria agent. Piperaquine tetraphosphate shows inhibition for chloroquine-sensitive and the chloroquine-resistant isolates. Piperaquine tetraphosphate in combination with dihydroartemisinin has the potential for the research of chloroquine-resistant malaria .

HY-134563

Z-Asp(OMe)-Gln-Met-Asp(OMe)-FMK	Caspase Apoptosis	Cancer
Z-Asp(OMe)-Gln-Met-Asp(OMe)-FMK is an inhibitor for caspase-3, and inhibits Dihydroartemisinin (HY-N0176) and Dictamnine (HY-N0849) co-induced apoptosis .

HY-N0402R

Artemether (Standard) Dihydroqinghaosu methyl ether (Standard); dihydroartemisinin methyl ether (Standard); SM224 (Standard)	Reference Standards Parasite	Infection Inflammation/Immunology Cancer
Artemether (Standard) is the analytical standard of Artemether. This product is intended for research and analytical applications. Artemether is an anti-malarial compound that targets drug-resistant strains of falciparum malaria .

HY-N0176S6

Dihydroartemisinin-d Dihydroqinghaosu-d; β-dihydroartemisinin-d; Artenimol-d	Isotope-Labeled Compounds Parasite NF-κB Autophagy Reactive Oxygen Species (ROS) Drug Metabolite	Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Dihydroartemisinin-d (Dihydroqinghaosu-d) is the deuterium labeled Dihydroartemisinin (HY-N0176). Dihydroartemisinin is an orally active metabolite of rtemisinin (HY-B0094) and antimalarial agent. Dihydroartemisinin induces Autophagy by inhibiting NF-κB activation. Dihydroartemisinin promotes ROS accumulation. Dihydroartemisinin exhibits anticancer activity in esophageal cancer cells. Dihydroartemisinin shows schistosomicidal activity against juvenile and adult worms of Schistosoma japonicum, reduces worm burden, and displays antiparasitic activity. Dihydroartemisinin can be used in research related to multiple myeloma, promyelocytic leukemia, esophageal cancer, and Schistosoma japonicum infection.

HY-160962

SM1044	Caspase Apoptosis	Cancer
SM1044 is a dihydroartemisinin (DHA) dimer. SM1044 activates caspase, induces apooptosis in RL95-2 and KLE cells. SM1044 inhibits proliferations of cancer cells RL95-2, KLE, HEC-50, HEC-1-A, HEC-1-B, AN3CA, with IC₅₀ < 3.6 μM . SM1044 inhbits tumor growth in RL95-2 xenograft mouse model .

HY-W768856

Artemether-13C,d3 Dihydroqinghaosu methyl ether-¹³C,d₃; dihydroartemisinin methyl ether-¹³C,d₃; SM224-¹³C,d₃	Isotope-Labeled Compounds Parasite	Infection Inflammation/Immunology Cancer
Artemether- ¹³C,d₃ (Dihydroqinghaosu methyl ether- ¹³C,d₃) is the deuterium and ¹³C-labeled Artemether (HY-N0402). Artemether is an anti-malarial compound that targets drug-resistant strains of falciparum malaria .

HY-183574

Antimalarial agent 62	Parasite	Infection
Antimalarial agent 62 is an orally active imidazopyridine-6-carboxamide antimalarial agent with a high resistance barrier. Antimalarial agent 62 kills trophozoite-stage Plasmodium ring forms, effectively clears dihydroartemisinin-induced dormant Plasmodium ring forms, and eliminates parasitemia in mice infected with Plasmodium yoelii. In AReBaR resistance omics screening, Antimalarial agent 62 is not affected by different target- and efflux-mediated resistance mutations and can withstand resistance selection. Antimalarial agent 62 has been applied to studies of malaria-related mechanisms .

Cat. No.	Product Name	Type

HY-143218

TPE-MI 10+ Cited Publications Tetraphenylethene maleimide	Fluorescent Dyes
TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasites Plasmodium falciparum .

TPE-MI

10+ Cited Publications

Tetraphenylethene maleimide

Fluorescent Dyes

TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasites Plasmodium falciparum .

HY-DY1024

TPE-MI (solution)	Fluorescent Dyes
TPE-MI (Tetraphenylethene maleimide) (solution) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasitesPlasmodium falciparum . Solvent and concentration: DMSO: 10 mM

TPE-MI (solution)

Fluorescent Dyes

TPE-MI (Tetraphenylethene maleimide) (solution) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasitesPlasmodium falciparum .
Solvent and concentration: DMSO: 10 mM

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0176

*Dihydroartemisinin* 40+ Cited Publications Dihydroqinghaosu; β-dihydroartemisinin; Artenimol	Infection Structural Classification Classification of Application Fields Terpenoids Sesquiterpenes Artemisia carvifolia Buch.-Ham. ex Roxb. Plants Compositae Disease Research Fields Source Classification	Parasite NF-κB Autophagy Reactive Oxygen Species (ROS) Drug Metabolite
Dihydroartemisinin is an orally active metabolite of rtemisinin (HY-B0094) and antimalarial agent. Dihydroartemisinin induces Autophagy by inhibiting NF-κB activation. Dihydroartemisinin promotes ROS accumulation. Dihydroartemisinin exhibits anticancer activity in esophageal cancer cells. Dihydroartemisinin shows schistosomicidal activity against juvenile and adult worms of Schistosoma japonicum, reduces worm burden, and displays antiparasitic activity. Dihydroartemisinin can be used in research related to multiple myeloma, promyelocytic leukemia, esophageal cancer, and Schistosoma japonicum infection .

HY-N0402

Artemether 3 Publications Verification Dihydroqinghaosu methyl ether; dihydroartemisinin methyl ether; SM224	Classification of Application Fields Terpenoids Sesquiterpenes Artemisia carvifolia Buch.-Ham. ex Roxb. Plants Compositae Disease Research Fields Source Classification Cancer	Parasite
Artemether is an anti-malarial compound that targets drug-resistant strains of falciparum malaria .

HY-N0176R

Dihydroartemisinin (Standard) Dihydroqinghaosu (Standard); β-dihydroartemisinin (Standard); Artenimol (Standard)	Structural Classification Terpenoids Sesquiterpenes Artemisia carvifolia Buch.-Ham. ex Roxb. Plants Compositae Source Classification	Reference Standards Parasite NF-κB Autophagy Apoptosis
Dihydroartemisinin (Standard) is the analytical standard of Dihydroartemisinin. This product is intended for research and analytical applications. Dihydroartemisinin is a potent anti-malaria agent.

HY-N0402R

Artemether (Standard) Dihydroqinghaosu methyl ether (Standard); dihydroartemisinin methyl ether (Standard); SM224 (Standard)	Structural Classification Terpenoids Sesquiterpenes Artemisia carvifolia Buch.-Ham. ex Roxb. Plants Compositae Source Classification	Reference Standards Parasite
Artemether (Standard) is the analytical standard of Artemether. This product is intended for research and analytical applications. Artemether is an anti-malarial compound that targets drug-resistant strains of falciparum malaria .

Cat. No.	Product Name	Chemical Structure

HY-N0402S

Artemether-d3
Artemether-d₃ is the deuterium labeled Artemether. Artemether is an antimalarial for the treatment of resistant strains of falciparum malaria.

HY-N0176S

Dihydroartemisinin-d3
Dihydroartemisinin-d₃ is the deuterium labeled Dihydroartemisinin. Dihydroartemisinin is a potent anti-malaria agent.

HY-W754303

Dihydroartemisinin-13C,d5
Dihydroartemisinin- ¹³C,d₅ (Dihydroqinghaosu- ¹³C,d₅) is the deuterium labeled and ¹³C-labeled Dihydroartemisinin (HY-N0176). Dihydroartemisinin is a potent anti-malaria agent.

HY-N0176S3

Dihydroartemisinin-d5
Dihydroartemisinin-d₅ is deuterated labeled Dihydroartemisinin (HY-N0176). Dihydroartemisinin is a potent anti-malaria agent.

HY-N0176S6

Dihydroartemisinin-d
Dihydroartemisinin-d (Dihydroqinghaosu-d) is the deuterium labeled Dihydroartemisinin (HY-N0176). Dihydroartemisinin is an orally active metabolite of rtemisinin (HY-B0094) and antimalarial agent. Dihydroartemisinin induces Autophagy by inhibiting NF-κB activation. Dihydroartemisinin promotes ROS accumulation. Dihydroartemisinin exhibits anticancer activity in esophageal cancer cells. Dihydroartemisinin shows schistosomicidal activity against juvenile and adult worms of Schistosoma japonicum, reduces worm burden, and displays antiparasitic activity. Dihydroartemisinin can be used in research related to multiple myeloma, promyelocytic leukemia, esophageal cancer, and Schistosoma japonicum infection.

Dihydroartemisinin-d

Dihydroartemisinin-d (Dihydroqinghaosu-d) is the deuterium labeled Dihydroartemisinin (HY-N0176). Dihydroartemisinin is an orally active metabolite of rtemisinin (HY-B0094) and antimalarial agent. Dihydroartemisinin induces Autophagy by inhibiting NF-κB activation. Dihydroartemisinin promotes ROS accumulation. Dihydroartemisinin exhibits anticancer activity in esophageal cancer cells. Dihydroartemisinin shows schistosomicidal activity against juvenile and adult worms of Schistosoma japonicum, reduces worm burden, and displays antiparasitic activity. Dihydroartemisinin can be used in research related to multiple myeloma, promyelocytic leukemia, esophageal cancer, and Schistosoma japonicum infection.

HY-W768856

Artemether-13C,d3
Artemether- ¹³C,d₃ (Dihydroqinghaosu methyl ether- ¹³C,d₃) is the deuterium and ¹³C-labeled Artemether (HY-N0402). Artemether is an anti-malarial compound that targets drug-resistant strains of falciparum malaria .

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dihydroartemisinin

Inhibitors & Agonists

Fluorescent Dyes

NaturalProducts

Isotope-Labeled Compounds

Natural
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