143 Results for "

enterococcus

" in MedChemExpress (MCE) Product Catalog:
Products (143)

143 Results for "enterococcus" in MCE Product Catalog:

11
11 Publications Verification
Cat. No.: HY-124617
CAS No.: 441022-64-6
Purity:  99.44%
Target:  

Apoptosis Bacterial

Research Areas:  

Infection Cancer

AMXT-1501 is a Bacterial agent and polyamine transport system inhibitor. AMXT-1501 targets membrane phospholipids and exhibits antibacterial activity against a variety of Gram-positive and Gram-negative multidrug-resistant bacteria . AMXT-1501 inhibits capsular biosynthesis in Streptococcus pneumoniae . AMXT-1501 targets ornithine decarboxylase and polyamines to inhibit the proliferation of neuroblastoma cells . AMXT-1501 in combination with DFMO (HY-B0744) induces Apoptosis in neuroblastoma cells. AMXT-1501 is applicable to research related to multidrug-resistant bacterial infections, pneumococcal infections, Streptococcus pneumoniae infections, and neuroblastoma .
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2
2 Cited Publications
Cat. No.: HY-D0256
CAS No.: 1937-37-7
Synonyms: Chlorazol Black E; Ferristatin II disodium; C.I. 30235
Direct Black 38 (Chlorazol Black E) is a benzidine-based azo dye, a substrate of Enterococcus gallinarum, and is mainly used for textile dyeing. Direct Black 38 is biodegradable after being reduced by microbial enzymes (such as Enterococcus gallinarum azoreductase), breaking the azo bonds and releasing benzidine and 4-aminobiphenyl. Direct Black 38 can be used in environmental toxicology, wastewater treatment and carcinogenicity studies, but its metabolite benzidine is listed as a human carcinogen .
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2
2 Cited Publications
Cat. No.: HY-N0656A
CAS No.: 7562-61-0
(+)-Usnic acid is isolated from isolated from lichens, binds at the ATP-binding pocket of mTOR, and inhibits mTORC1/2 activity. (+)-Usnic acid inhibits the phosphorylation of mTOR downstream effectors: Akt (Ser473), 4EBP1, S6K, induces autophay, with anti-cancer and anti-inflammatory activity. (+)-Usnic acid possesses antimicrobial activity against a number of planktonic gram-positive bacteria, including Staphylococcus aureus, Enterococcus faecalis, and Enterococcus faecium .
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2
2 Cited Publications
Cat. No.: HY-134978
CAS No.: 2204289-53-0
Purity:  99.40%
Target:  

SHMT Bacterial

Research Areas:  

Others

(Rac)-SHIN2 is a pyrazolopyran derivative and a serine hydroxymethyltransferase (SHMT) inhibitor. (Rac)-SHIN2 has antibacterial activity and low cytotoxicity against Hep2 cells. (Rac)-SHIN2 exerts potent antibacterial activity against both vancomycin-susceptible and vanA-type vancomycin-resistant Enterococcus .
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1
1 Cited Publications
Cat. No.: HY-A0097
CAS No.: 61036-62-2
Synonyms: Antibiotic MDL-507; MDL-507
Teicoplanin is a glycopeptide antibiotic indicated for use in serious infections caused by Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus and Enterococcus aureus.Teicoplanin shows antiviral activity for HIV-1, SARS-CoV1 and SARS-CoV2. Teicoplanin sodium shows anti-MRSA activity .
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1
1 Cited Publications
Cat. No.: HY-129434A
CAS No.: 21651-62-7
Purity:  99.69%
4aα,7α,7aα-Nepetalactone exhibits antibacterial activity, and inhibits Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella typhi and Enterococcus faecalis.
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1
1 Cited Publications
Cat. No.: HY-135813
CAS No.: 877950-01-1
Purity:  95.05%
Target:  

Bacterial

Research Areas:  

Infection

LtaS-IN-1 (compound 1771) is a potent small-molecule inhibitor of Lipoteichoic acid (LTA) synthesis in multidrug-resistant (MDR) E. faecium and by altering the cell wall morphology. LtaS-IN-1 alone inhibits Enterococcus.spp 28 strains with varying MIC values ranging from 0.5 μg/mL to 64 μg/mL. LtaS-IN-1 combination with antibiotics abolishs multidrug-resistant E. faecium growth almost completely .
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Cat. No.: HY-N10264
CAS No.: 269741-97-1
Synonyms: (+)-Avrainvillamide; CJ-17,665
Avrainvillamide ((+)-Avrainvillamide) is a naturally occurring alkaloid with antiproliferative effects, binds to the nuclear chaperone nucleophosmin, a proposed oncogenic protein that is overexpressed in many different human tumors. Avrainvillamide affects cell biology both by directly binding NPM1 and Crm1 as well as by inhibiting the association of these proteins with certain native cellular partners. Avrainvillamide, an antibiotic, inhibits growth of multi-agent resistant Staphylococcus aureus, Streptococcus pyogenes, and Enterococcus faecalis, with MICs of 12.5, 12.5 and 25 μg/ml, respectively .
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Cat. No.: HY-A0279
CAS No.: 270076-60-3
Synonyms: Pristinamycine
Pristinamycin, produced by Streptomyces pristinaespiralis, is an orally active streptogramin-like antibiotic consisting of two chemically unrelated components: Pristinamycin I (PI) and Pristinamycin II (PII). Pristinamycin is highly active against many antibiotic-resistant pathogens, particularly Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin-resistant S. aureus (VRSA) and Enterococcus faecium (VREF) .
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Cat. No.: HY-N10765
CAS No.: 120278-22-0
Salvinolone is active against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE). Salvinolone shows cytotoxic activity with an IC50 of 47.6 μM against the HL-60 tumor cell line for 72 h .
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Cat. No.: HY-N125722
CAS No.: 33538-71-5
Synonyms: Aabomycin A1
Venturicidin A (Aabomycin A1), from actinomycetes, is a membrane-active natural product inhibitor of ATP synthase. Venturicidin A potentiates the aminoglycoside antibiotic gentamicin against multidrug-resistant clinical isolates of Staphylococcus, Enterococcus, and Pseudomonas aeruginosa. Venturicidin A shows noticeable toxicity toward human embryonic-kidney (HEK)cells with an IC50 of 31 μg/mL.
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Cat. No.: HY-N13668
CAS No.: 468757-69-9
Rhodomyrtone is an antibiotic that can be found in the leaves of Rhodomyrtus tomentosa. Rhodomyrtone kills Gram-positive bacterial cells without causing bacteriolysis. Rhodomyrtone exhibits activity against a variety of Gram-positive bacteria, including Bacillus cereus, Bacillus subtilis, Enterococcus faecalis, Staphylococcus epidermidis, Streptococcus gordonii, Streptococcus pneumoniae, Streptococcus pyogenes and Streptococcus salivarius. Rhodomyrtone is applicable to studies related to bacterial infections .
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Cat. No.: HY-N2198
CAS No.: 22136-74-9
Podocarpusflavone A is a biflavonoid present in the leaves of Podocarpus henkelii, with anti-tumor, topoisomerase I inhibitory, antibacterial and antifungal activities. Podocarpusflavone A exhibits antibacterial activity against Enterococcus faecalis and Pseudomonas aeruginosa. Podocarpusflavone A shows weak activity against fungal pathogens. Podocarpusflavone A targets topoisomerase I and induces cell cycle arrest and apoptosis in MCF-7 cells. Podocarpusflavone A can be used for studies on cancer, bacterial and fungal infections .
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Cat. No.: HY-Y1106
CAS No.: 7778-53-2
Tripotassium phosphate is a Bactericid with bactericidal activity primarily against Gram-negative bacteria. Tripotassium phosphate reduces the population counts of Enterobacteriaceae and Campylobacter in poultry skin rinsates. Tripotassium phosphate fails to reduce the population count of Enterococcus in poultry skin rinsates .
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Cat. No.: HY-129034
CAS No.: 76168-82-6
Purity:  92.45%
Ramoplanin is a broad-spectrum lipoglycodepsipeptide antibiotic derived from the Actinoplanes spp with with activity against gram-positive bacteria .
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Cat. No.: HY-N7652
CAS No.: 564-13-6
Terminolic acid is a pentacyclic triterpene glycoside and antibacterial agent. Terminolic acid can be isolated from Combretum racemosum. Terminolic acid inhibits proinflammatory cytokines by binding to the receptor active sites of IL-1β and IL-6. Terminolic acid reduces IL-8. Terminolic acid has antibacterial activity against Staphylococcus aureus, Escherichia coli and Enterococcus faecalis with MICs ranging from 64 to 256 μg/mL. Terminolic acid is used in colon cancer research .
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Cat. No.: HY-W002016
CAS No.: 253-52-1
Phthalazine is a chemical scaffold. Phthalazine derivatives act as VEGFR-2 inhibitors, PARP-1 inhibitors, and anticancer agents. The complex of phthalazine with silver exhibits broad-spectrum antibacterial and antifungal activities against Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa PAO1, and Candida albicans. Phthalazine derivatives possess potent vasodilatory activity. Phthalazine can be used in research related to colon adenocarcinoma, breast cancer, hypertension, diabetes, and microbial infections .
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Cat. No.: HY-N0129
CAS No.: 564-20-5
Sclareolide is isolated from the flower of Perilla frutescens with antibacterial and cytotoxic activities .
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Cat. No.: HY-P5203
CAS No.: 2764845-22-7
Synonyms: EntK1
Target:  

Bacterial

Research Areas:  

Infection

Enterocin K1 (EntK1) is a bacteriocin. Enterocin K1 is a ribosomal synthetic peptide. Enterocin K1 specifically targets Enterococcus faecalis via the Eep protein on the bacterial membrane. Enterocin K1 displays a potent antibacterial activity against VRE. Enterocin K1 can be used for related studies of VRE infections .
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Cat. No.: HY-120397
CAS No.: 159428-42-9
Purity:  95.64%
Target:  

PROTAC Linkers

Research Areas:  

Infection Cancer

Bis-propargyl-PEG4 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG4 is used for the synthesis of demethylvancomycin dimers . Bis-propargyl-PEG4 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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