1. Anti-infection
  2. Bacterial
    Antibiotic
  3. Ramoplanin

Ramoplanin 

Cat. No.: HY-129034
Handling Instructions

Ramoplanin is a broad-spectrum lipoglycodepsipeptide antibiotic derived from the Actinoplanes spp with with activity against gram-positive bacteria.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Ramoplanin Chemical Structure

Ramoplanin Chemical Structure

CAS No. : 76168-82-6

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Description

Ramoplanin is a broad-spectrum lipoglycodepsipeptide antibiotic derived from the Actinoplanes spp with with activity against gram-positive bacteria[1][2].

IC50 & Target

Bacteria[1]

In Vitro

Ramoplanin exerts its bactericidal activity against gram-positive aerobic and anaerobic bacteria by blocking peptidoglycan synthesis via lipid II[1].

In Vivo

Ramoplanin (100, 500 μg/ml; p.o.; for 8 days) suppresses vancomycin-resistant Enterococcus (VRE) to undetectable level during treatment[1].

Animal Model: Female CF1 mice (25-30 g)[1]
Dosage: 100 μg/ml, 500 μg/ml
Administration: Oral administration; for 8 days
Result: Developed undetectable levels of VRE in stool during treatment.
CAS No.

76168-82-6

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

RamoplaninBacterialAntibioticlipoglycodepsipeptideantibioticvancomycin-resistantEnterococcusInhibitorinhibitorinhibit

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Ramoplanin
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