33538-71-5
Chemical Structure
Venturicidin A
Synonym(s): Aabomycin A1
- CAS No.: 33538-71-5
- Formula:C41H67NO11
- Molecular Weight:749.97
IUPAC Name: (2R,3R,4R,6R)-3-hydroxy-6-(((1R,5S,6R,8R,9E,11R,15Z,17R)-1-hydroxy-5-((2R,4R,5S,6S)-5-hydroxy-4,6-dimethyl-7-oxononan-2-yl)-6,8,16,18-tetramethyl-3-oxo-4,21-dioxabicyclo[15.3.1]henicosa-9,15,18-trien-11-yl)oxy)-2-methyltetrahydro-2H-pyran-4-yl carbamate
InChIKey: HHQKNFDAEDTRJK-KXQVSFSQSA-N
SMILES: CC1=CC[C@](O)(C2)O[C@]1([H])/C(C)=C\CCC[C@](O[C@@]3([H])C[C@H]([C@H](O)[C@@H](C)O3)OC(N)=O)([H])/C=C/[C@H](C)C[C@@H](C)[C@]([C@H](C)C[C@@H](C)[C@H](O)[C@H](C)C(CC)=O)([H])OC2=O
Biological Activity: Venturicidin A (Aabomycin A1), from actinomycetes, is a membrane-active natural product inhibitor of ATP synthase. Venturicidin A potentiates the aminoglycoside antibiotic gentamicin against multidrug-resistant clinical isolates of Staphylococcus, Enterococcus, and Pseudomonas aeruginosa. Venturicidin A shows noticeable toxicity toward human embryonic-kidney (HEK)cells with an IC50 of 31 μg/mL.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Venturicidin A | 96.6% | Venturicidin A (Aabomycin A1), from actinomycetes, is a membrane-active natural product inhibitor of ATP synthase. Venturicidin A potentiates the aminoglycoside antibiotic gentamicin against multidrug-resistant clinical isolates of Staphylococcus, Enterococcus, and Pseudomonas aeruginosa. Venturicidin A shows noticeable toxicity toward human embryonic-kidney (HEK)cells with an IC50 of 31 μg/mL. | ||||||||||||||||||||
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Keywords
