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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
glutamate carboxypeptidase-II
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "glutamate carboxypeptidase-II" in MCE Product Catalog:
7
7 Cited Publications
Synonyms: 2-(Phosphonomethyl)pentanedioic acid
Target:
Research Areas:
2-PMPA (2-(Phosphonomethyl)pentanedioic acid) is a glutamate carboxypeptidase II (GCPII) inhibitor with an IC50 of 0.0003 μM. 2-PMPA shows low blood-brain barrier penetration. 2-PMPA sodium blocks the hydrolysis of NAAG, regulates glutamate levels in the brain and neurovascular coupling. 2-PMPA is applicable to the research of neurological diseases .
7
7 Cited Publications
Cat. No.: HY-100788C
CAS No.: 373645-42-2
Synonyms: 2-(Phosphonomethyl)pentanedioic acid sodium
Target:
Research Areas:
2-PMPA (2-(Phosphonomethyl)pentanedioic acid) sodium is a glutamate carboxypeptidase II (GCPII) inhibitor with an IC50 of 0.0003 μM. 2-PMPA sodium shows low blood-brain barrier penetration. 2-PMPA sodium blocks the hydrolysis of NAAG, regulates glutamate levels in the brain and neurovascular coupling. 2-PMPA sodium is applicable to the research of neurological diseases .
Cat. No.: HY-W096171
CAS No.: 5796-17-8
Synonyms: 3-Hydroxy-D-tyrosine
Target:
Research Areas:
Synonyms: GPI-5693
Target:
Research Areas:
2-MPPA (GPI-5693) is an orally active and selective glutamate carboxypeptidase II (GCP II; PSMA) inhibitor with an IC50 of 90 nM .
Cat. No.: HY-103344
CAS No.: 723331-20-2
Target:
Research Areas:
ZJ43 is a NAAG peptidase inhibitor and glutamate carboxypeptidase II/III (GCP II/III) inhibitor with human GCP II IC50 of 2.4 nM and Ki of 0.8 nM. ZJ43 blocks N-acetylaspartylglutamate hydrolysis, elevates extracellular N-acetylaspartylglutamate levels, and activates group II metabotropic glutamate receptors (mGluR). ZJ43 can be used for the research of schizophrenia, inflammatory pain, neuropathic pain, and traumatic brain injury .
Cat. No.: HY-100788R
CAS No.: 173039-10-6
Synonyms: 2-(Phosphonomethyl)pentanedioic acid (Standard)
Target:
Research Areas:
2-PMPA (2-(Phosphonomethyl)pentanedioic acid) Standard is the analytical standard of 2-PMPA (HY-100788). This product is intended for research and analytical applications. 2-PMPA (2-(Phosphonomethyl)pentanedioic acid) sodium is a glutamate carboxypeptidase II (GCPII) inhibitor with an IC50 of 0.0003 μM. 2-PMPA sodium shows low blood-brain barrier penetration. 2-PMPA sodium blocks the hydrolysis of NAAG, regulates glutamate levels in the brain and neurovascular coupling. 2-PMPA sodium is applicable to the research of neurological diseases.
Cat. No.: HY-175863
Target:
Research Areas:
2-PMPA prodrug 1 is an orally active prodrug of 2-PMPA (HY-100788), a glutamate carboxypeptidase II (GCPII) inhibitor. 2-PMPA prodrug 1 effectively delivers 2-PMPA into the bloodstream and produces sustained 2-PMPA exposure in plasma. 2-PMPA prodrug 1 can be used in the research of GCPII-related peripheral diseases, including prostate cancer and inflammatory bowel disease .
Cat. No.: HY-103345R
CAS No.: 254737-29-6
Synonyms: GPI-5693 (Standard)
Target:
Research Areas:
2-MPPA (Standard) is the analytical standard of 2-MPPA. This product is intended for research and analytical applications. 2-MPPA (GPI-5693) is an orally active and selective glutamate carboxypeptidase II (GCP II; PSMA) inhibitor with an IC50 of 90 nM .
Cat. No.: HY-P70548A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FOLH1; Folylpoly-Gamma-glutamate carboxypeptidase; Prev. FOLH; Membrane glutamate carboxypeptidase; NAALAD1; glutamate Carboxylase II; GCPII; NAALADase I; PSMA; NAALAdase; PSM; FGCP; glutamate carboxypeptidase II; MGCP; glutamate carboxypeptidase 2; Folat
Species:
Human
Source:
HEK293
Cat. No.: HY-P71240
Purity: ≥ 90%, as determined by Bis-Tris PAGE.
Synonyms: FOLH1; Folylpoly-Gamma-glutamate carboxypeptidase; Prev. FOLH; Membrane glutamate carboxypeptidase; NAALAD1; glutamate Carboxylase II; GCPII; NAALADase I; PSMA; NAALAdase; PSM; FGCP; glutamate carboxypeptidase II; MGCP; glutamate carboxypeptidase 2; Folat
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P78026
Purity: ≥ 90%, as determined by Bis-Tris PAGE.
Synonyms: FOLH1; Folylpoly-Gamma-glutamate carboxypeptidase; Prev. FOLH; Membrane glutamate carboxypeptidase; NAALAD1; glutamate Carboxylase II; GCPII; NAALADase I; PSMA; NAALAdase; PSM; FGCP; glutamate carboxypeptidase II; MGCP; glutamate carboxypeptidase 2; Folat
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P704853
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FOLH1; Folylpoly-Gamma-glutamate carboxypeptidase; Prev. FOLH; Membrane glutamate carboxypeptidase; NAALAD1; glutamate Carboxylase II; GCPII; NAALADase I; PSMA; NAALAdase; PSM; FGCP; glutamate carboxypeptidase II; MGCP; glutamate carboxypeptidase 2; Folat
Species:
Human
Source:
HEK293
Cat. No.: HY-P704854
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FOLH1; Folylpoly-Gamma-glutamate carboxypeptidase; Prev. FOLH; Membrane glutamate carboxypeptidase; NAALAD1; glutamate Carboxylase II; GCPII; NAALADase I; PSMA; NAALAdase; PSM; FGCP; glutamate carboxypeptidase II; MGCP; glutamate carboxypeptidase 2; Folat
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P76703
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FOLH1; Folylpoly-Gamma-glutamate carboxypeptidase; Prev. FOLH; Membrane glutamate carboxypeptidase; NAALAD1; glutamate Carboxylase II; GCPII; NAALADase I; PSMA; NAALAdase; PSM; FGCP; glutamate carboxypeptidase II; MGCP; glutamate carboxypeptidase 2; Folat
Species:
Human
Source:
HEK293
Cat. No.: HY-P70548
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FOLH1; Folylpoly-Gamma-glutamate carboxypeptidase; Prev. FOLH; Membrane glutamate carboxypeptidase; NAALAD1; glutamate Carboxylase II; GCPII; NAALADase I; PSMA; NAALAdase; PSM; FGCP; glutamate carboxypeptidase II; MGCP; glutamate carboxypeptidase 2; Folat
Species:
Human
Source:
HEK293
Cat. No.: HY-P704852
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FOLH1; Folylpoly-Gamma-glutamate carboxypeptidase; Prev. FOLH; Membrane glutamate carboxypeptidase; NAALAD1; glutamate Carboxylase II; GCPII; NAALADase I; PSMA; NAALAdase; PSM; FGCP; glutamate carboxypeptidase II; MGCP; glutamate carboxypeptidase 2; Folat
Species:
Human
Source:
HEK293
Cat. No.: HY-P705073
Purity: ≥ 90%, as determined by Bis-Tris PAGE.
Synonyms: FOLH1; Folylpoly-Gamma-glutamate carboxypeptidase; Prev. FOLH; Membrane glutamate carboxypeptidase; NAALAD1; glutamate Carboxylase II; GCPII; NAALADase I; PSMA; NAALAdase; PSM; FGCP; glutamate carboxypeptidase II; MGCP; glutamate carboxypeptidase 2; Folat
Species:
Human
Source:
HEK293
Cat. No.: HY-P705074
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: FOLH1; Folylpoly-Gamma-glutamate carboxypeptidase; Prev. FOLH; Membrane glutamate carboxypeptidase; NAALAD1; glutamate Carboxylase II; GCPII; NAALADase I; PSMA; NAALAdase; PSM; FGCP; glutamate carboxypeptidase II; MGCP; glutamate carboxypeptidase 2; Folat
Species:
Human
Source:
HEK293
Cat. No.: HY-P705075
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FOLH1; Folylpoly-Gamma-glutamate carboxypeptidase; Prev. FOLH; Membrane glutamate carboxypeptidase; NAALAD1; glutamate Carboxylase II; GCPII; NAALADase I; PSMA; NAALAdase; PSM; FGCP; glutamate carboxypeptidase II; MGCP; glutamate carboxypeptidase 2; Folat
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P705076
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FOLH1; Folylpoly-Gamma-glutamate carboxypeptidase; Prev. FOLH; Membrane glutamate carboxypeptidase; NAALAD1; glutamate Carboxylase II; GCPII; NAALADase I; PSMA; NAALAdase; PSM; FGCP; glutamate carboxypeptidase II; MGCP; glutamate carboxypeptidase 2; Folat
Species:
Mouse
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
