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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
guanine moiety
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "guanine moiety" in MCE Product Catalog:
Research Areas:
AUTAC1 is a MetAP2-targeting autophagy-mediated degrader (AUTAC). AUTACs contain a degradation tag and a warhead to provide target specificity. AUTAC1 contains an FBnG (p-Fluorobenzyl Guanine) and a Fumagillol moiety. Fumagillol binds covalently to MetAP2 .
Research Areas:
AUTAC2 is a FKBP12-targeting autophagy-mediated degrader (AUTAC). AUTAC2 contains an FBnG (p-Fluorobenzyl Guanine) and an SLF (c ligand of FKBP) moiety. SLF binds non-covalently to FKBP12 .
Target:
Research Areas:
9-Ethylguanine is a modified nucleobase derived from guanine that coordinates to azolato-bridged dinuclear platinum(II) complexes via its N7 nitrogen atom. 9-Ethylguanine forms adducts with a ruthenium(II) complex via the N7 position of its guanine moiety .
Cat. No.: HY-D3603
CAS No.: 928817-42-9
Target:
Research Areas:
Benzylguanine-CY5 is a quenched fluorescent dye conjugate based on benzylguanine (BG). Benzylguanine-CY5 possesses the activity of specifically covalently labeling SNAP-tag fusion proteins. Benzylguanine-CY5 exhibits intramolecular fluorescence quenching in the unbound state; upon binding to SNAP-tag, the quenching guanine moiety is cleaved, and its fluorescence intensity increases. Benzylguanine-CY5 can be used for background-free specific fluorescent labeling and imaging studies of SNAP-tag fusion proteins in living cells .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
