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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
heat-stressed
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "heat-stressed" in MCE Product Catalog:
6
6 Publications Verification
Synonyms: Trimethylglycine; carboxy-N,N,N-trimethylmethanaminium
3
3 Cited Publications
Research Areas:
Mitoquinol is an orally active mitochondria-targeted antioxidant. Mitoquinol can regulate mitochondrial respiration and oxidation. Mitoquinol inhibits ROS production, and improves phagocytosis and glycolysis in ethanol-exposed macrophages via the HIF-1α-PFKP axis. Additionally, Mitoquinol can partially alleviate heat stress-induced decreases in growth performance, inflammatory responses, and metabolic disorders in pigs .
1
1 Cited Publications
Cat. No.: HY-N6924
CAS No.: 80930-74-1
Category:
Infection Panax notoginseng (Burkill) F. H. Chen ex C. H. Chow Panax japonicas C. A. Mey. Metabolic Disease Plants Disease Research Fields Araliaceae Saccharides
Target:
Cat. No.: HY-W012382
CAS No.: 537-55-3
Category:
Metabolic Disease Endocrine diseases Endogenous metabolite Human Gut Microbiota Metabolites Microorganisms Monophenols Ketones, Aldehydes, Acids Disease markers Phenols Disease Research Fields
Target:
Synonyms: Olomoucin
Research Areas:
Butyrolactone I is an orally active and ATP-competitive inhibitor of CDK1. Butyrolactone I inhibits NF-κB, cdc2 kinase, Bax, ROS production, modulates the PERK/CHOP. Butyrolactone I mitigates heat-stress-induced Apoptosis. Butyrolactone I shows anti-inflammatory and intestinal protective activity. Butyrolactone I has antitumor effects against non-small cell lung, small cell lung, prostate cancer and leukemia. Butyrolactone I can be used in NASH research .
Cat. No.: HY-W015466
CAS No.: 96-81-1
Synonyms: Trimethylglycine (Standard); carboxy-N,N,N-trimethylmethanaminium (Standard)
Cat. No.: HY-W012382S
Cat. No.: HY-B0710S
CAS No.: 309762-22-9
Synonyms: Trimethylglycine-13C3; Carboxy-N,N,N-trimethylmethanaminium-13C3
Cat. No.: HY-141564
CAS No.: 2837939-81-6
Target:
Research Areas:
RyR1-IN-1 (Compound 1) is a RyR1 inhibitor with an IC50 of 12 nM. RyR1-IN-1 blocks Ca²⁺ release and inhibits muscle tetany caused by caffeine and heat stress. RyR1-IN-1 can completely prevent the increase in body temperature and death caused by isoflurane and heat stress. RyR1-IN-1 can be used for the study of heat stroke .
Cat. No.: HY-W012382R
CAS No.: 537-55-3
Cat. No.: HY-W015466S
CAS No.: 355808-21-8
Research Areas:
Acetylvaline- 15N is the 15N-labeled Acetylvaline (HY-W015466). Acetylvaline is a class of amino acid derivative metabolites. The expression abundance of Acetylvaline is upregulated under heat stress conditions; it participates in the regulation of amino acid biosynthesis, cysteine and methionine metabolic pathways, and mediates the physiological processes of antioxidant defense and energy metabolism reprogramming in Magallana sikamea. Acetylvaline can be released from acetylvalyl-RNA of Turnip Yellow Mosaic Virus (TYMV) by N‑acylaminoacyl‑tRNA hydrolase. Acetylvaline can be used in metabolism-related research .
Cat. No.: HY-W015466S1
Research Areas:
Acetylvaline- 13C2 is the 13C-labeled Acetylvaline (HY-W015466). Acetylvaline is a class of amino acid derivative metabolites. The expression abundance of Acetylvaline is upregulated under heat stress conditions; it participates in the regulation of amino acid biosynthesis, cysteine and methionine metabolic pathways, and mediates the physiological processes of antioxidant defense and energy metabolism reprogramming in Magallana sikamea. Acetylvaline can be released from acetylvalyl-RNA of Turnip Yellow Mosaic Virus (TYMV) by N‑acylaminoacyl‑tRNA hydrolase. Acetylvaline can be used in metabolism-related research .
Cat. No.: HY-W015466R
CAS No.: 96-81-1
Cat. No.: HY-N13240
Category:
Target:
Cat. No.: HY-124410S
Cat. No.: HY-W414697
CAS No.: 40289-37-0
Synonyms: D-Ribo-phytosphingosine (C17 base)
4-Hydroxysphinganine C17 base (D-Ribo-phytosphingosine C17 base), also known as D-ribo-phytosphingosine or PHS, is a crucial compound present in the membranes of fungi, plants, bacteria, marine organisms, and mammalian tissues. It plays a vital role in preserving the structural integrity of membranes, regulating cellular growth, and mediating the heat stress response in yeast. Additionally, PHS serves as a precursor for the synthesis of important lipid mediators such as PHS 1-phosphate, inositol phosphorylceramide, and KRN7000 (the α-anomer of galactosylceramide). Furthermore, this phospholipid promotes keratinocyte differentiation, making it a valuable active ingredient in cosmetic formulations.
Cat. No.: HY-181794
CAS No.: 1005147-23-8
Z19024498 is a heat sensitizer. Z19024498 inhibits SAFB granule formation under heat stress conditions. Z19024498 enhances heat stress-induced Apoptosis. Z19024498 exerts anticancer activity against cervical cancer in synergy with heat stress .
Cat. No.: HY-W753416
CAS No.: 457603-63-3
Target:
Research Areas:
14-Hydroxylated brassinosteroid is a plant growth regulator. 14-Hydroxylated brassinosteroid enhances winter wheat resistance to heat stress, delays heat-induced leaf senescence, maintains leaf water content, promotes grain filling, and mitigates yield loss. 14-Hydroxylated brassinosteroid shows antioxidant activity. 14-Hydroxylated brassinosteroid can be used for the research of plant growth .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
