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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
human 5-HT2A serotonin receptor
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "human 5-HT2A serotonin receptor" in MCE Product Catalog:
4
4 Cited Publications
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Tegaserod is an orally active serotonin receptor 4 (HTR4; 5-HT4R) agonist and a 5-HT2B receptor antagonist. Tegaserod has pKis of 7.5, 8.4 and 7.0 for human recombinant 5-HT2A, 5-HT2B and 5-HT2C receptors, respectively. Tegaserod causes tumor cell apoptosis, blunts PI3K/Akt/mTOR signaling and decreases S6 phosphorylation. Tegaserod has anti-tumor activity and has the potential for irritable bowel syndrome (IBS) research .
4
4 Cited Publications
Synonyms: SDZ-HTF-919; HTF-919
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Tegaserod maleate (SDZ-HTF-919) is an orally active serotonin receptor 4 (HTR4; 5-HT4R) agonist and a 5-HT2B receptor antagonist. Tegaserod maleate has pKis of 7.5, 8.4 and 7.0 for human recombinant 5-HT2A, 5-HT2B and 5-HT2C receptors, respectively. Tegaserod maleate causes tumor cell apoptosis, blunts PI3K/Akt/mTOR signaling and decreases S6 phosphorylation. Tegaserod maleate has anti-tumor activity and has the potential for irritable bowel syndrome (IBS) research .
1
1 Cited Publications
Synonyms: Clorotepine maleate salt
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Octoclothepin (Clorotepine) maleate salt is a D2 dopamine receptor antagonist and 5-HT2 serotonin receptor antagonist , with Ki values of 0.67 nM, 0.57 nM, and 0.19 nM for the dopamine D2, 5-HT2A, and 5-HT2C receptors, respectively. Octoclothepin maleate salt also binds to adrenergic receptors, with Ki values of 0.66 nM, 0.56 nM, and 0.77 nM for α1a, α1b, and α1d, respectively. Octoclothepin maleate salt can be used in schizophrenia research .
1
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Octoclothepin (Clorotepine) is a D2 dopamine receptor antagonist and 5-HT2 serotonin receptor antagonist , with Ki values of 0.67 nM, 0.57 nM, and 0.19 nM for the dopamine D2, 5-HT2A, and 5-HT2C receptors, respectively. Octoclothepin also binds to adrenergic receptors, with Ki values of 0.66 nM, 0.56 nM, and 0.77 nM for α1a, α1b, and α1d, respectively. Octoclothepin can be used in schizophrenia research .
Synonyms: MDL11939
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Glemanserin (MDL11939) is a potent and selective antagonist for serotonin receptor 5-HT2A (Ki=2.89, 0.54 and 2.5 nM for rat 5-HT2A, rabbit 5-HT2A and human 5-HT2A, respectively) .
Cat. No.: HY-118796
CAS No.: 77872-41-4
Synonyms: 4-HO-MET; 4-Hydroxy-N-methyl-N-ethyltryptamine
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4-Hydroxy MET (4-HO-MET; 4-Hydroxy-N-methyl-N-ethyltryptamine) is a synthetic tryptamine psychoactive substance. 4-Hydroxy MET is a partial 5-HT2A receptor agonist, a serotonin transporter inhibitor and weak norepinephrine transporter inhibitor. 4-Hydroxy MET affects emotional, motoric, and cognitive functions via serotonergic hallucinogenic activity .
Cat. No.: HY-103115
CAS No.: 443144-27-2
Synonyms: EMD 281014; LY 2422347 hydrochloride
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Pruvanserin hydrochloride (EMD 281014) is a selective serotonin 5-HT2A receptor antagonist with IC50 values of 0.35 nM and 1 nM for human and rat 5-HT2A receptors. Pruvanserin (hydrochloride) can be used for the research of schizophrenia .
Cat. No.: HY-P703149
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HTR2A; serotonin receptor 2A; Prev. HTR2; serotonin 5-HT-2A receptor; 5-HT2A; 5-HT2 receptor; 5-Hydroxytryptamine (serotonin) receptor 2A, G Protein-Coupled; 5-HT-2A; 5-Hydroxytryptamine (serotonin) receptor 2A; 5-Hydroxytryptamine receptor 2A; 5-HT-2
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P703150
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HTR2A; serotonin receptor 2A; Prev. HTR2; serotonin 5-HT-2A receptor; 5-HT2A; 5-HT2 receptor; 5-Hydroxytryptamine (serotonin) receptor 2A, G Protein-Coupled; 5-HT-2A; 5-Hydroxytryptamine (serotonin) receptor 2A; 5-Hydroxytryptamine receptor 2A; 5-HT-2
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-130351
CAS No.: 1566571-52-5
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25H-NBOMe hydrochloride is an agonist for the rat and human serotonin 5-HT2A receptors with Ki values of 1.19 and 2.83 nM, respectively .
Cat. No.: HY-101250R
CAS No.: 107703-78-6
Synonyms: MDL11939 (Standard)
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Glemanserin (Standard) is the analytical standard of Glemanserin. This product is intended for research and analytical applications. Glemanserin (MDL11939) is a potent and selective antagonist for serotonin receptor 5-HT2A (Ki=2.89, 0.54 and 2.5 nM for rat 5-HT2A, rabbit 5-HT2A and human 5-HT2A, respectively) .
Cat. No.: HY-W741145
Research Areas:
Dibenzepine-d3 is the deuterated-labeled Dibenzepine (HY-12391). Dibenzepine is a blood-brain barrier permeable ligand of the histamine H1 receptor (Histamine H1 Receptor), with a Ki value of 0.02 μM. Dibenzepine exhibits varying degrees of affinity for multiple serotonin receptors and dopamine receptors. Dibenzepine can be used in research related to depression, schizophrenia, dementia, and non-specific agitation .
Cat. No.: HY-14153S
CAS No.: 1134188-56-9
Cat. No.: HY-P810892
Synonyms: HTR2; 5-hydroxytryptamine receptor 2A; 5-HT-2; 5-HT-2A; serotonin receptor 2A
Cat. No.: HY-W682464
CAS No.: 96096-53-6
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4-MeO-MiPT is a serotonin transporter (SERT) inhibitor and serotonin 2A receptor (5-HT2A) agonist with pIC50 and IC50 values of 57 nM and 0.43 nM for human SERT, and pEC50 and EC50 values of 23 nM and 2.3 nM for human 5-HT2A, respectively. 4-MeO-MiPT blocks serotonin uptake via SERT, acts as an agonist at 5-HT2A receptors, and exhibits agonist activity at 5-HT1A, 5-HT1D, 5-HT2B, and 5-HT2C receptors. 4-MeO-MiPT can be used for the research of depression .
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Dibenzepine is a blood-brain barrier permeable ligand of the histamine H1 receptor (Histamine H1 Receptor), with a Ki value of 0.02 μM. Dibenzepine exhibits varying degrees of affinity for multiple serotonin receptors and dopamine receptors. Dibenzepine can be used in research related to depression, schizophrenia, dementia, and non-specific agitation .
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Research Areas:
Dibenzepine hydrochloride is a blood-brain barrier permeable ligand of the histamine H1 receptor (Histamine H1 Receptor), with a Ki value of 0.02 μM. Dibenzepine hydrochloride exhibits varying degrees of affinity for multiple serotonin receptors and dopamine receptors. Dibenzepine hydrochloride can be used in research related to depression, schizophrenia, dementia, and non-specific agitation .
Cat. No.: HY-106587B
CAS No.: 41932-42-7
Synonyms: Clorotepine dimaleate
Research Areas:
Octoclothepin (Clorotepine) dimaleate is a D2 dopamine receptor antagonist and 5-HT2 serotonin receptor antagonist , with Ki values of 0.67 nM, 0.57 nM, and 0.19 nM for the dopamine D2, 5-HT2A, and 5-HT2C receptors, respectively. Octoclothepin dimaleate also binds to adrenergic receptors, with Ki values of 0.66 nM, 0.56 nM, and 0.77 nM for α1a, α1b, and α1d, respectively. Octoclothepin dimaleate can be used in schizophrenia research .
Cat. No.: HY-N20747
CAS No.: 28363-70-4
Synonyms: 4-Hydroxy-N-methyltryptamine; 4-HO-NMT
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
