13448-22-1
Chemical Structure
Octoclothepine
Synonym(s): Clorotepine
- CAS No.: 13448-22-1
- Formula:C19H21ClN2S
- Molecular Weight:344.90
IUPAC Name: 1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-4-methylpiperazine
InChIKey: XRYLGRGAWQSVQW-UHFFFAOYSA-N
SMILES: CN1CCN(C2CC3=CC=CC=C3SC4=CC=C(Cl)C=C24)CC1
Biological Activity: Octoclothepin (Clorotepine) is a D2 dopamine receptor antagonist and 5-HT2 serotonin receptor antagonist , with Ki values of 0.67 nM, 0.57 nM, and 0.19 nM for the dopamine D2, 5-HT2A, and 5-HT2C receptors, respectively. Octoclothepin also binds to adrenergic receptors, with Ki values of 0.66 nM, 0.56 nM, and 0.77 nM for α1a, α1b, and α1d, respectively. Octoclothepin can be used in schizophrenia research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Octoclothepine | 99.90% | Octoclothepin (Clorotepine) is a D2 dopamine receptor antagonist and 5-HT2 serotonin receptor antagonist , with Ki values of 0.67 nM, 0.57 nM, and 0.19 nM for the dopamine D2, 5-HT2A, and 5-HT2C receptors, respectively. Octoclothepin also binds to adrenergic receptors, with Ki values of 0.66 nM, 0.56 nM, and 0.77 nM for α1a, α1b, and α1d, respectively. Octoclothepin can be used in schizophrenia research. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
Keywords
