4789-68-8
Chemical Structure
Octoclothepin maleate salt
Synonym(s): Clorotepine maleate salt
- CAS No.: 4789-68-8
- Formula:C23H25ClN2O4S
- Molecular Weight:460.97
IUPAC Name: 1-(8-chloro-10,11-dihydrodibenzo[b,f]thiepin-10-yl)-4-methylpiperazine maleate
InChIKey: GWKBZIADWSOIQV-BTJKTKAUSA-N
SMILES: CN1CCN(C2CC3=CC=CC=C3SC4=CC=C(Cl)C=C24)CC1.O=C(O)/C=C\C(O)=O
Biological Activity: Octoclothepin (Clorotepine) maleate salt is a D2 dopamine receptor antagonist and 5-HT2 serotonin receptor antagonist , with Ki values of 0.67 nM, 0.57 nM, and 0.19 nM for the dopamine D2, 5-HT2A, and 5-HT2C receptors, respectively. Octoclothepin maleate salt also binds to adrenergic receptors, with Ki values of 0.66 nM, 0.56 nM, and 0.77 nM for α1a, α1b, and α1d, respectively. Octoclothepin maleate salt can be used in schizophrenia research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Octoclothepin maleate salt | 98.81% | Octoclothepin (Clorotepine) maleate salt is a D2 dopamine receptor antagonist and 5-HT2 serotonin receptor antagonist , with Ki values of 0.67 nM, 0.57 nM, and 0.19 nM for the dopamine D2, 5-HT2A, and 5-HT2C receptors, respectively. Octoclothepin maleate salt also binds to adrenergic receptors, with Ki values of 0.66 nM, 0.56 nM, and 0.77 nM for α1a, α1b, and α1d, respectively. Octoclothepin maleate salt can be used in schizophrenia research. | ||||||||||||||||||||
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Keywords
