96096-53-6
Chemical Structure
4-MeO-MiPT
- CAS No.: 96096-53-6
- Formula:C15H22N2O
- Molecular Weight:246.35
IUPAC Name: N-(2-(4-methoxy-1H-indol-3-yl)ethyl)-N-methylpropan-2-amine
InChIKey: BJIWLHLNPTWSGD-UHFFFAOYSA-N
SMILES: COC1=C2C(CCN(C(C)C)C)=CNC2=CC=C1
Biological Activity: 4-MeO-MiPT is a serotonin transporter (SERT) inhibitor and serotonin 2A receptor (5-HT2A) agonist with pIC50 and IC50 values of 57 nM and 0.43 nM for human SERT, and pEC50 and EC50 values of 23 nM and 2.3 nM for human 5-HT2A, respectively. 4-MeO-MiPT blocks serotonin uptake via SERT, acts as an agonist at 5-HT2A receptors, and exhibits agonist activity at 5-HT1A, 5-HT1D, 5-HT2B, and 5-HT2C receptors. 4-MeO-MiPT can be used for the research of depression[1].
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4-MeO-MiPT | 4-MeO-MiPT is a serotonin transporter (SERT) inhibitor and serotonin 2A receptor (5-HT2A) agonist with pIC50 and IC50 values of 57 nM and 0.43 nM for human SERT, and pEC50 and EC50 values of 23 nM and 2.3 nM for human 5-HT2A, respectively. 4-MeO-MiPT blocks serotonin uptake via SERT, acts as an agonist at 5-HT2A receptors, and exhibits agonist activity at 5-HT1A, 5-HT1D, 5-HT2B, and 5-HT2C receptors. 4-MeO-MiPT can be used for the research of depression. | |||||||||||||||||||||
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