5 Results for "

human K562 cell line

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "human K562 cell line" in MCE Product Catalog:

Cat. No.: HY-103694
CAS No.: 550-33-4
Purity:  98.44%
Synonyms: 9-β-D-Ribofuranosylpurine
Nebularine (9-β-D-Ribofuranosylpurine) is a naturally occurring cytotoxic purine riboside antibiotic. Nebularine competitively inhibits adenine deaminase and xanthine oxidase, and acts as a template for thymine insertion during DNA elongation and replication. Nebularine serves as a cytokinin antagonist and induces mitotic aberrations in plant cells. Nebularine exhibits cytotoxicity against plants, mammals, fungal organisms and cancer cells. Nebularine can be used in research related to fungal infections, plant growth, as well as chronic myeloid leukemia, acute lymphoblastic leukemia and breast cancer .
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Cat. No.: HY-N15582
CAS No.: 3600-95-1
Perezone is a sesquiterpenoid benzoquinone found in the roots of Acourtia species. Perezone inhibits the activity of leukemia cell line K-562 and human glioma cell line U-251 (IC50: 6.83 μM). Perezone increases the expression of caspase 3, 8, and 9 genes associated with apoptosis. Perezone has antioxidant and anti-inflammatory activities .
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Cat. No.: HY-128634
CAS No.: 2235393-30-1
Target:  

Apoptosis PI3K MEK

Research Areas:  

Cancer

CML-IN-1 (compound 7) is a potent anticancer agent. CML-IN-1 displays very good induced-apoptosis effect for human chronic myeloid leukemia (CML) cell line K562. CML-IN-1 exerts its effect via a significantly reduced protein phosphorylation of PI3K/Akt signal pathway. CML-IN-1 (compound 4) also inhibits cell proliferation by suppressing the MEK/ERK signaling pathway in colorectal cancer .
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Cat. No.: HY-125322
CAS No.: 144860-69-5
Target:  

Bacterial

Research Areas:  

Infection

Reveromycin C is a polyketide originally isolated from Streptomyces that has antifungal activity against C. albicans (MICs=2.0 and >500 μg/mL at pH 3 and 7.4, respectively). Reveromycin C inhibits EGF-induced mitogenic activity in the Balb/MK mouse epidermal cell line. It also reverses the morphology of sarcoma-virus-transformed NRK rat kidney cells (EC50=1.58 μg/mL) and inhibits proliferation of KB cells and K562 human chronic myelogenous leukemia cells (IC50=2.0 μg/mL for both).
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Cat. No.: HY-N21770
CAS No.: 303088-44-0
Densiflorol A is a bibenzyl compound and anticancer agent. Densiflorol A can be isolated from Bulbophyllum kwangtungense. Densiflorol A exhibits antitumor activity against leukemia and cervical cancer .
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