11 Results for "

human leucocytes

" in MedChemExpress (MCE) Product Catalog:
Products (11)

11 Results for "human leucocytes" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-P9934
CAS No.: 143653-53-6
Synonyms: C7E3

Target:  

Integrin

Research Areas:  

Cardiovascular Disease

Abciximab (C7E3), a chimeric mouse/human monoclonal antibody fragment, is a glycoprotein (GP) IIb/IIIa inhibitor. Abciximab inhibits platelet aggregation and leucocyte adhesion by binding to the glycoprotein IIb/IIIa, vitronectin and Mac-1 receptors .
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Cat. No.: HY-N4148
CAS No.: 108648-07-3
Purpureaside C, phenolic glycoside, is a minichromosome maintenance complex component 6 (MCM6) inhibitor. Purpureaside C binds to the ATP-pocket of MCM6, suppresses MCM6 protein expression in gastric cancer cells. Purpureaside C suppresses gastric cancer cell growth and induces apoptosis. Purpureaside C exerts antibacterial activity and proinflammatory activity. Purpureaside C can be used for the researches of gastric cancer, bacterial infection and inflammation .
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Cat. No.: HY-E70005L
CAS No.: 9001-12-1
Target:  

Proteasome

Research Areas:  

Metabolic Disease

Collagenase (Type B, animal free) is an animal-free collagen-degrading digestive enzyme and tissue dissociation reagent. Collagenase (Type B, animal free) can digest mouse aorta, myocardium, human umbilical cord, and human liver tissue to isolate primary leukocytes, adult mouse cardiomyocytes, human mesenchymal stem cells, and individual hepatocytes. Collagenase (Type B, animal free) can be used in studies related to liver cirrhosis .
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Cat. No.: HY-D1633
CAS No.: 126938-14-5
4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate is a fluorescent dye. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate undergoes desulphation by galactose-6-sulphate sulphatase to form 4-methylumbelliferyl-β-D-galactopyranoside, which is cleaved by β-galactosidase to release fluorescent 4-methylumbelliferone. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate interacts with N-acetylgalactosamine-6-sulfate sulfatase (GALNS) via hydrogen bonds, electrostatic interactions, and steric interactions. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate serves as a substrate in assays measuring galactose-6-sulphate sulphatase and GALNS activity. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate can be used for the research of Morquio disease type A (mucopolysaccharidosis IV A) .
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Cat. No.: HY-100397
CAS No.: 51798-45-9
Purity:  85.00%
Category:  

Microorganisms

Target:  

Elastase

Elastatinal is a potent and competitive inhibitor of elastase, with a Ki of 0.21 μM. Elastatinal more potently inhibits pancreatic elastase versus leucocyte elastase. Elastatinal shows no activity on human leucocyte chymotrypsin-like protease .
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Cat. No.: HY-P1901
CAS No.: 872036-64-1
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Insulin alpha-chain (1-13) is a human leucocyte antigen (HLA)-DR4-restricted epitope comprising the first 13 amino acids of the insulin A-chain .
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Cat. No.: HY-126988
CAS No.: 70857-49-7
Synonyms: α-MAPI
Target:  

Elastase

Research Areas:  

Others

SP-Chymostatin B (α-MAPI) is a strong inhibitor of many proteases, including chymotrypsin, papain, chymotrypsin-like serine proteinases, chymases, and lysosomal cysteine proteinases such as cathepsins A,B,C, H, and L. SP-Chymostatin B weakly inhibits human leucocyte elastase .
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Cat. No.: HY-W009640
CAS No.: 2210-63-1
Target:  

Drug Derivative COX

Research Areas:  

Inflammation/Immunology

Mofebutazone is a pyrazolidinedione non-steroidal anti-inflammatory agent (NSAID). Mofebutazone exhibits weak COX inhibition, no effect on LOX, and slightly suppresses the percentage of leukocyte phagocytosis in vitro. Mofebutazone can be used in research related to soft tissue rheumatism .
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Cat. No.: HY-W009640A
CAS No.: 41468-34-2
Target:  

Drug Derivative COX

Research Areas:  

Inflammation/Immunology

Mofebutazone sodium is a pyrazolidinedione non-steroidal anti-inflammatory agent (NSAID). Mofebutazone sodium exhibits weak COX inhibition, no effect on LOX, and slightly suppresses the percentage of leukocyte phagocytosis in vitro. Mofebutazone sodium can be used in research related to soft tissue rheumatism .
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Cat. No.: HY-150181
CAS No.: 1609659-32-6
Target:  

Integrin

Research Areas:  

Inflammation/Immunology

IBE-667 is a LFA-1 integrin agonist with a Kd value of 52 nM. IBE-667 increases the stability of the open conformation of LFA-1 and enhances its affinity for ICAM-1. IBE-667 can be used in studies related to leukocyte adhesion deficiency .
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Cat. No.: HY-106706
CAS No.: 39577-20-3
Synonyms: Auteral; BM 15100
Target:  

Histamine Receptor

Research Areas:  

Inflammation/Immunology

Picumast (Auteral; BM 15100) is an orally active antiallergic agent with histamine receptor antagonistic activity. Picumast inhibits allergy-related cascade reactions by suppressing mediator release from tissue mast cells while exerting histamine antagonistic effects. Picumast inhibits allergic reactions in rats, guinea pigs, and cynomolgus monkeys. Picumast can be used in allergy-related research .
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