39577-20-3
Chemical Structure
Picumast
Synonym(s): Auteral; BM 15100
- CAS No.: 39577-20-3
- Formula:C25H31Cl3N2O3
- Molecular Weight:513.88
IUPAC Name: 7-(3-(4-(4-chlorobenzyl)piperazin-1-yl)propoxy)-3,4-dimethyl-2H-chromen-2-one hydrochloride
InChIKey: AMHVERUFVROLJA-UHFFFAOYSA-N
SMILES: O=C1OC2=C(C(C)=C1C)C=CC(OCCCN3CCN(CC3)CC4=CC=C(C=C4)Cl)=C2.Cl.Cl
Biological Activity: Picumast (Auteral; BM 15100) is an orally active antiallergic agent with histamine receptor antagonistic activity. Picumast inhibits allergy-related cascade reactions by suppressing mediator release from tissue mast cells while exerting histamine antagonistic effects. Picumast inhibits allergic reactions in rats, guinea pigs, and cynomolgus monkeys. Picumast can be used in allergy-related research[1].
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Picumast | Picumast (Auteral; BM 15100) is an orally active antiallergic agent with histamine receptor antagonistic activity. Picumast inhibits allergy-related cascade reactions by suppressing mediator release from tissue mast cells while exerting histamine antagonistic effects. Picumast inhibits allergic reactions in rats, guinea pigs, and cynomolgus monkeys. Picumast can be used in allergy-related research. | |||||||||||||||||||||
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