41468-34-2
41468-34-2
Chemical Structure
Mofebutazone sodium
- CAS No.: 41468-34-2
- Formula:C13H15N2NaO2
- Molecular Weight:254.26
IUPAC Name: sodium 4-butyl-3,5-dioxo-2-phenylpyrazolidin-1-ide
InChIKey: FIIOKODLPLWGDK-UHFFFAOYSA-M
SMILES: O=C(C1CCCC)[N-]N(C2=CC=CC=C2)C1=O.[Na+]
Biological Activity: Mofebutazone sodium is a pyrazolidinedione non-steroidal anti-inflammatory agent (NSAID). Mofebutazone sodium exhibits weak COX inhibition, no effect on LOX, and slightly suppresses the percentage of leukocyte phagocytosis in vitro. Mofebutazone sodium can be used in research related to soft tissue rheumatism[1][2].
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Mofebutazone sodium | Mofebutazone sodium is a pyrazolidinedione non-steroidal anti-inflammatory agent (NSAID). Mofebutazone sodium exhibits weak COX inhibition, no effect on LOX, and slightly suppresses the percentage of leukocyte phagocytosis in vitro. Mofebutazone sodium can be used in research related to soft tissue rheumatism. | |||||||||||||||||||||
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References
- [1]. Neumüller J, et al. Comparative in vitro investigations of the influence of mofebutazone, phenylbutazone and diclofenac on phagocytosis and respiratory burst of human peripheral blood leucocytes. Arzneimittel-Forschung. 1994 May;44(5):636-41. [Content Brief]
- [2]. Coersmeier C, et al. Effect of anti-inflammatory and analgesic pyrazoles on arachidonic acid metabolism in isolated heart and gastric mucosa preparations. Agents and actions. Supplements. 1986;19:137-54. [Content Brief]
Keywords
