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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
human liver microsomal CYP3A4
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "human liver microsomal CYP3A4" in MCE Product Catalog:
Category:
Other Monoterpenes Terpenoids Other Diseases Plants Umbelliferae Vernonia Schreb. Disease Research Fields
Target:
Cat. No.: HY-117580
CAS No.: 13951-70-7
Synonyms: OH-PRED
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Research Areas:
16α-Hydroxyprednisolone (OH-PRED) is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid Budesonide (HY-13580). 16α-Hydroxyprednisolone formation is catalyzed by isoenzymes within the cytochrome P450 3A (CYP3A) subfamily. 16α-Hydroxyprednisolone formation can be inhibited by antibodies targeting the CYP3A subfamily .
Cat. No.: HY-E72102
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Research Areas:
Human CYP3A4, Reductase+b5 refers to a near-physiological recombinant microsomal system co-expressed in insect cells, consisting of human cytochrome P450 3A4, NADPH-P450 oxidoreductase (CPR) and cytochrome b5. Human CYP3A4 is a human cytochrome P450 subtype belonging to the CYP3 family, as well as a major metabolic enzyme. It is predominantly expressed in human liver and intestine, metabolizes a variety of active compounds, and activates multiple procarcinogens .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
