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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
52 Results for "
human low-density lipoprotein
" in MedChemExpress (MCE) Product Catalog:
Products (52)
52 Results for "human low-density lipoprotein" in MCE Product Catalog:
2
Target:
Research Areas:
2
2 Cited Publications
Cat. No.: HY-P70235
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LDLR; LDL Receptor; low density lipoprotein Receptor; low-density lipoprotein Receptor Class A Domain-Containing Protein 3; low-density lipoprotein Receptor; Familial Hypercholesterolemia; LDLCQ2; low density lipoprotein
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P76478A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LRPAP1; low density lipoprotein-Related Protein-Associated Protein 1 (Alpha-2-Macroglobulin Receptor-Associated Protein 1); Prev. A2MRAP; low density lipoprotein Receptor-Related Protein-Associated Protein 1; Prev. RAP; 39 KDa Receptor-Associated Protein
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P72961
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXCL16; CXCLG16; C-X-C Motif Chemokine Ligand 16; Scavenger Receptor For Phosphatidylserine And Oxidized low density lipoprotein; SR-PSOX; Chemokine (C-X-C Motif) Ligand 16; SRPSOX; Small-Inducible Cytokine B16; Transmembrane Chemokine CXCL16; CXC Chemoki
Species:
Human
Source:
HEK293
Cat. No.: HY-126356
CAS No.: 35418-59-8
Target:
Cat. No.: HY-N0627
CAS No.: 16290-07-6
Category:
Flavonols other families Flavonoids Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-P10502
CAS No.: 2378836-93-0
Cat. No.: HY-P10697A
Target:
Research Areas:
Cat. No.: HY-P10502A
Cat. No.: HY-177291
CAS No.: 256397-11-2
Research Areas:
LAB687 is a microsomal triglyceride transfer protein (MTP) inhibitor with an IC50 of 0.9 nM for apolipoprotein B (apoB) secretion in HepG2 cells. LAB687 also acts as a Smoothened (Smo) antagonist, with IC50 values of 2.48 μM and 3.42 μM against mouse and human Smo receptors, respectively. LAB687 reduces triglyceride and low-density lipoprotein cholesterol (LDL-C) levels, and inhibits the Hedgehog signaling pathway. LAB687 can be used in studies related to Hedgehog-dependent cancers .
Cat. No.: HY-172661
CAS No.: 2661053-09-2
Research Areas:
Kylo-0603 is an orally active thyroid hormone receptor β (THR-β) agonist with an EC50 of 31.07 nM against human targets, and it exhibits much higher selectivity for THR-β than for THR-α. Kylo-0603 enables hepatocyte-targeted delivery via GalNAc modification. Kylo-0603 reduces serum cholesterol and low-density lipoprotein cholesterol levels. Kylo-0603 alleviates hepatic steatosis, inflammatory responses, hepatocyte ballooning, and non-alcoholic steatohepatitis activity scores. Kylo-0603 inhibits the progression of hepatic fibrosis. Kylo-0603 can be used for research on metabolic dysfunction-associated steatohepatitis (MASH) .
Cat. No.: HY-NP012A
Synonyms: Dil LDL
Cat. No.: HY-17504D
CAS No.: 1242184-42-4
Research Areas:
(3S,5R)-Rosuvastatin is the (3S,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM . Rosuvastatin potently blocks human ether-a-go-go related gene (hERG) current with an IC50 of 195 nM . Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin is very effective in lowering low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels .
Cat. No.: HY-P10697
Target:
Research Areas:
Cat. No.: HY-NP012B
Synonyms: Ac LDL
Cat. No.: HY-147279
CAS No.: 2643306-81-2
Milpocitide is a low-density lipoprotein receptor (human LDL receptor, LDLR), (293-333)-peptide fragment (EGF-like domain 1) .
Cat. No.: HY-NP012C
Synonyms: Ac-Dil LDL
Cat. No.: HY-126551
CAS No.: 474944-25-7
Research Areas:
Butenoyl-PAF is a phospholipid analog of platelet activating factor (PAF-like) that is generated in oxidized low-density lipoprotein (DLDR). Butenoyl-PAF can activate cells that express human PAF receptors, such as neutrophils, monocytes, and platelets, and it stimulates an increase in intracellular calcium ion concentration .
Cat. No.: HY-P704756
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LDLR; LDL Receptor; low density lipoprotein Receptor; low-density lipoprotein Receptor Class A Domain-Containing Protein 3; low-density lipoprotein Receptor; Familial Hypercholesterolemia; LDLCQ2; low density lipoprotein
Species:
Human
Source:
HEK293
Cat. No.: HY-P704757
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LDLR; LDL Receptor; low density lipoprotein Receptor; low-density lipoprotein Receptor Class A Domain-Containing Protein 3; low-density lipoprotein Receptor; Familial Hypercholesterolemia; LDLCQ2; low density lipoprotein
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
