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indica

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acetyl-CoA Carboxylase (1) Apoptosis (10) Autophagy (2) Bacterial (8) Bcl-2 Family (1) Biochemical Assay Reagents (1) Caspase (3) CDK (4) Cholinesterase (ChE) (2) DNA/RNA Synthesis (1) Drug Derivative (3) Dynamin (2) EBV (1) Endogenous Metabolite (2) Environmental Pollutants (3) Fungal (2) Glutaminase (1) Herbicide (4) Histone Acetyltransferase (2) HIV (1) HSP (1) iGluR (1) Influenza Virus (1) Insecticide (1) Interleukin Related (2) mGluR (1) Microtubule/Tubulin (1) Mitochondrial Metabolism (2) MMP (1) Monoamine Oxidase (1) MyD88 (2) NF-κB (2) NO Synthase (1) p38 MAPK (1) Parasite (4) Phosphatase (1) Phosphodiesterase (PDE) (2) PI3K (1) Reactive Oxygen Species (ROS) (1) Reference Standards (5) Survivin (1) Toll-like Receptor (TLR) (2) Topoisomerase (1) Wnt (2)
By Research Areas:	Cancer (14) Cardiovascular Disease (2) Infection (15) Inflammation/Immunology (13) Metabolic Disease (4) Neurological Disease (5)
Click Chemistry:	Alkynes (1)

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Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-107569

Garcinol 5 Publications Verification	Cholinesterase (ChE) Histone Acetyltransferase Apoptosis Endogenous Metabolite	Inflammation/Immunology Cancer
Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC₅₀s of 0.66 μM and 7.39 μM, respectively . Garcinol also inhibits histone acetyltransferases (HATs, IC₅₀= 7 μM) and p300/CPB-associated factor (PCAF, IC₅₀ = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity .

HY-N0703

Schaftoside Maximum Cited Publications 8 Publications Verification	Toll-like Receptor (TLR) MyD88 Dynamin Mitochondrial Metabolism Autophagy	Inflammation/Immunology
Schaftoside is a flavonoid found in a variety of Chinese herbal medicines, such as Eleusine indica. Schaftoside inhibits the expression of TLR4 and Myd88. Schaftoside also decreases Drp1 expression and phosphorylation, and reduces mitochondrial fission .

HY-W004263

1-Eicosanol Arachidyl alcohol	Environmental Pollutants Fungal	Infection
1-Eicosanol (Arachidyl alcohol) is a long-chain fatty alcohol and volatile organic compound that can be isolated from the leaves of Leea indica and produced by Bacillus velezensis ZJ1. 1-Eicosanol inhibits mycelial growth of Alternaria solani and Botrytis cinerea. 1-Eicosanol is applicable to research related to tomato early blight and tomato gray mold .

HY-123026

Salannin	Bacterial	Infection
Salannin, a limonoid bitter principle of the seed oil of Azadirachta indica, shows antiulcer and spermicidal activities. Salannin displays antibacterial activity towards both Gram-positive and Gram-negative bacteria .

HY-116035

Nimbolide 2 Publications Verification	Wnt NF-κB CDK Apoptosis	Cancer
Nimbolide is a triterpene compound that can be isolated from neem (Azadirachta indica), possesses anticancer and antiproliferative activity. Nimbolide induces tumor cell apoptosis by inhibiting NF-κB and CDK4/CDK6 kinase. Nimbolide suppresses the Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways .

HY-12597

Quisqualic acid L-Quisqualic acid	iGluR mGluR	Neurological Disease
Quisqualic acid (L-Quisqualic acid), a natural analog of glutamate, is a potent and pan two subsets (iGluR and mGluR) of excitatory amino acid (EAA) agonist with an EC₅₀ of 45 nM and a K_i of 10 nM for mGluR1R. Quisqualic acid is isolated from the fruits of Quisqualis indica .

HY-N5038

Mauritianin	Topoisomerase	Cardiovascular Disease Neurological Disease Metabolic Disease
Mauritianin is an orally active kaempferol glycoside. Mauritianin can be isolated from the flowers and leaves of Acalypha indica. Mauritianin is a topoisomerase I inhibitor. Mauritianin has hepatoprotective, neuroprotective, and renoprotective activities. Mauritianin increases vascular tone when used in combination with Alcesefoliside (HY-N5049) .

HY-133108

Azadirachtin B	EBV Parasite Phosphatase Influenza Virus	Infection Metabolic Disease Inflammation/Immunology Cancer
Azadirachtin B is an limonoid isolated from seed kernels of Azadirachta indica. Azadirachtin B increases alkaline phosphatase (ALP) activity and stimulates osteoblast differentiation. Azadirachtin B is active against the Epstein-Barr virus early antigen (EBV-EA). Azadirachtin B has insecticidal, nematocidal, anticancer, anti-inflammatory, antiviral and osteogenic properties .

HY-N1465

Aristolochic acid D Aristolochic acid-IVa	Phosphodiesterase (PDE) CDK Interleukin Related	Inflammation/Immunology Cancer
Aristolochic acid D (Aristolochic acid-IVa) is an orally active PDE2 (IC₅₀: 4.673 μM) and CDK2 (IC₅₀: 25 μM) inhibitor that can be isolated from Aristolochia indica L. Aristolochic acid D exhibits anti-inflammatory activity and is non-carcinogenic and non-nephrotoxic. Aristolochic acid D can be used in the research of inflammation and tumor-related diseases .

HY-118921

Ovatodiolide	Apoptosis	Infection Inflammation/Immunology Cancer
Ovatodiolide is a compound that can be isolated from Anisomeles indica. Ovatodiolide has anti-bacterial and anti-inflammatory properties. Ovatodiolide also has anti-cancer activity that induces cell cycle G2/M arrest and apoptosis via a ROS-dependent ATM/ATR signaling pathways .

HY-N12461

Cucurbitacin F	Bacterial Caspase Apoptosis	Infection
Cucurbitacin F is a tetracyclic protostane-type triterpenoid with low toxicity, antibacterial and anti-inflammatory activities, and is also a related compound of Cucurbitacin B (HY-N0416). Cucurbitacin F widely exists in plants such as Cucurbitaceae plants, Quisqualis indica and Sorbaria sorbifolia. Cucurbitacin F acts as an actin aggregator and reduces cell viability in a dose-dependent manner. Cucurbitacin F induces apoptosis by triggering G2/M phase cell cycle arrest and activating the caspase-3-dependent apoptosis .

HY-N12394

Norwogonin-8-O-glucuronide	Reactive Oxygen Species (ROS) NO Synthase	Inflammation/Immunology
Norwogonin-8-O-glucuronide is a glucuronide that can be isolated from Scutellaria indica. Norwogonin-8-O-glucuronide has anti-inflammatory activity. Norwogonin-8-O-glucuronide is a flavone glycoside. Norwogonin-8-O-glucuronide inhibits NO production in macrophage RAW264.7 cells with an IC₅₀ above 30 μM .

HY-N9540

Methyl citrate	Monoamine Oxidase	Neurological Disease
Methyl citrate is a Monoamine oxidase B (MAO-B) inhibitor (IC₅₀=0.23 mM). Methyl citrate is isolated from the fruits of Opuntia ficus-indica var. saboten Makino .

HY-17531

Pyraclonil	Environmental Pollutants Herbicide	Others
Pyraclonil is a proporphyrinogen oxidase (PPO) inhibitor. Pyraclonil is a herbicide agent and is highly effective in controlling the susceptible (S) and multiple-herbicide-resistant (MHR) E. indica populations . Pyraclonil is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-N1710

28-Deoxonimbolide	Apoptosis Caspase	Cancer
28-Deoxonimbolide is a Nimbin (HY-N3187) type limonoid, that can be isolated from Azadirachta indica seed extracts. 28-Deoxonimbolide shows anticancer activity. 28-Deoxonimbolide induces apoptotic cell death in HL60 cells via both the mitochondrial- and the death receptor-mediated pathways .

HY-N10096

Epoxyazadiradione	Parasite	Infection
Epoxyazadiradione is a limonoid purified from neem (Azadirachta indica) fruits. Epoxyazadiradione inhibits the tautomerase activity of MIF of both human (huMIF) and malaria parasites (Plasmodium falciparum (PfMIF) and Plasmodium yoelii (PyMIF)) non-competitively in a reversible fashion (K_i, 2.11-5.23 μM). Epoxyazadiradione has the potential against proinflammatory reactions induced by MIF of both malaria parasites and human .

HY-N16474

Azadirachtin H	Drug Derivative	Inflammation/Immunology Cancer
Azadirachtin H is a triterpenoid found in Azadirachta indica. Azadirachta indica shows anti-infection, anti-inflammatory and anticancer activities. Azadirachtin H can be used for the researches of cancer, infection and inflammation .

HY-122764

Acalyphin	Others	Others
Acalyphin, a cyanogenic glucoside, is nature product that could be isolated from the aerial parts of Acalypha indica .

HY-N9898

Sinocrassoside C1	Others	Others
Sinocrassoside C1 is a natural compound isolated from themethanolic extract of the whole plant ofSinocrassula indica (Crassulaceae) .

HY-107569R

Garcinol (Standard)	Cholinesterase (ChE) Histone Acetyltransferase Apoptosis Endogenous Metabolite Reference Standards	Inflammation/Immunology Cancer
Garcinol (Standard) is the analytical standard of Garcinol. This product is intended for research and analytical applications. Garcinol, a polyisoprenylated benzophenone harvested from Garcinia indica, exerts anti-cholinesterase properties towards acetyl cholinesterase (AChE) and butyrylcholinesterase (BChE) with IC50s of 0.66 μM and 7.39 μM, respectively . Garcinol also inhibits histone acetyltransferases (HATs, IC50= 7 μM) and p300/CPB-associated factor (PCAF, IC50 = 5 μM). Garcinol has anti-inflammatory and anti-cancer activity .

HY-N9615

Azadiradione	HSP	Infection Neurological Disease Inflammation/Immunology
Azadiradione is a bioactive limonoid found in Azadirachta indica. Azadiradione is a HSF1 activator. Azadiradione has antimycobacterial, anti-nociceptive and anti-inflammatory activities .

HY-W763706A

Tamarind Gum from Tamarind seed, 98% Tamarind seed polysaccharide, 98%	Biochemical Assay Reagents	Others
Tamarind Gum from Tamarind seed, 98% (Tamarind seed polysaccharide, 98%) can be obtained from Tamarindus Indica L. Tamarind Gum from Tamarind seed is a polysaccharide thickener .

HY-N2876

Anisofolin A	Parasite Bacterial	Infection
Anisofolin A is a flavonoid that can be isolated from Anisomeles indica. Anisofolin A has antimalarial activity (IC₅₀: 4.39 μM), and antimycobacterium activity (IC₅₀: 4.50 μM) against M. tuberculosis H37Ra .

HY-175736

Herbicidal agent 11	Herbicide	Others
Herbicidal agent 11 (Compound 8a) is a herbicidal agent. Herbicidal agent 11 has significant postemergence herbicidal activities against the monocotyledonous weed Echinochloa crusgalli with inhibition of potent root and stem growth and has a good crop selectivity against wheat, maize, and oilseed rape. Herbicidal agent 11 also has effective inhibitory effects on Digitaria sanguinalis, Eclipta prostrate and Eleusine indica. Herbicidal agent 11 can be used for the development of herbicides .

HY-N3787

Ducheside A	Others	Others
Ducheside A is a ellagic glycoside that can be found in Ducheside indica Focke .

HY-N12111

S-(-)-N-trans-Feruloyl normetanephrine	Others	Neurological Disease
S-(-)-N-trans-Feruloyl normetanephrine is a nature product with weak anti-acetylcholinesterase activity. S-(-)-N-trans-Feruloyl normetanephrine can be isolated from the aerial parts of Bassia indica Wight .

HY-N2471

Aristolindiquinone	Others	Others
Aristolindiquinone can be isolated from Aristolwhia indica .

HY-121731

Nimbocinone	Others	Metabolic Disease
Nimbocinone, isolated from Azadirachta indica, exhibits antidiabetogenic activity .

HY-N3471

Isomangiferolic acid	Others	Others
Isomangiferolic acid is a Triterpenoids product that can be isolated from the herbs of Mangifera indica L. .

HY-N3326

Mangiferolic acid	Others	Others
Mangiferolic acid is a Triterpenoids product that can be isolated from the herbs of Mangifera indica L. .

HY-N3850

Erysenegalensein E	Others	Others
Erysenegalensein E is a Flavonoids product that can be isolated from the herbs of Erythrina indica .

HY-N3171A

(+)-Nortrachelogenin Wikstromol	Apoptosis PI3K	Cancer
(+)-Nortrachelogenin (Wikstromol), a pharmacologically ligand from from wikstroemia indica, possesses antileukemic activity .

HY-N1708

27-Hydroxymangiferonic acid	Insecticide Parasite	Others
27-Hydroxymangiferonic acid is a Triterpenoids product that can be isolated from the herbs of Mangifera indica .

HY-N3695

6-Deacetylnimbinene	Others	Others
6-Deacetylnimbinene is a triterpenoid product that can be isolated from Azadirachta indica A. Juss .

HY-W615780

Dihydromyrcene	Environmental Pollutants	Cardiovascular Disease
Dihydromyrcene is a volatile terpenoid compound found in essential oil from Rosa indica L. petals. Dihydromyrcene has potential vasorelaxant and antispasmodic effects .

HY-N8910

(7R)-Methoxy-8-epi-matairesinol	Others	Others
(7R)-Methoxy-8-epi-matairesinol is a Lignans product that can be isolated from the roots of Wikstroemia indica .

HY-159979

Dillenetin 3′,4′-Dimethoxyquercetin	Others	Cancer
Dillenetin is a flavonoid. Dillenetin can be isolated from the fruit of Dillenia indica. Dillenetin has anticancer activity against lung cancer and cervical cancer .

HY-163450

Nimbiol	Bacterial	Infection
Nimbiol exhibits binding energy for FtsZ and shows potential anti-FtsZ effect .

HY-N3694

Deacetylnimbin Desacetyl nimbin	Others	Others
Deacetylnimbin is a limonoid isolated from Azadirachta indica. Deacetylnimbin can be used as a plant metabolite, a food repellent and as a growth regulator for insects such as S. litura, P. ricini and O. fscovittata .

HY-N0703R

Schaftoside (Standard)	Reference Standards Toll-like Receptor (TLR) MyD88 Dynamin Mitochondrial Metabolism Autophagy	Inflammation/Immunology
Schaftoside (Standard) is the analytical standard of Schaftoside. This product is intended for research and analytical applications. Schaftoside is a flavonoid found in a variety of Chinese herbal medicines, such as Eleusine indica. Schaftoside inhibits the expression of TLR4 and Myd88. Schaftoside also decreases Drp1 expression and phosphorylation, and reduces mitochondrial fission .

HY-N1654

2',3'-Dehydrosalannol	Bacterial	Infection
2',3'-Dehydrosalannol is a potent antibacterial agent. 2',3'-Dehydrosalannol shows antibacterial activity against K. pneumonia ATCC 13883, P. aeruginosa ATCC 27853, S. aureus ATCC 25922, E. coli ATCC 11775, and E. faecalis ATCC 10541, with MIC values of 0.78, 1.56, 1.56, 6.25, and 25 μg/mL, respectively .

HY-N2939

Bis-5,5-Nortrachelogenin	Others	Others
Bis-5,5-Nortrachelogenin is isolated from active extract of root of Wikstroemia indica. Bis-5,5-Nortrachelogenin inhibits nitric oxide (NO) production in a lipopolysaccharide (LPS) and recombinant mouse interferon-γ(IFN-γ) activated murine macrophage-like cell line, RAW 264.7 with an IC₅₀ value of 48.6 mM .

HY-17531R

Pyraclonil (Standard)	Herbicide Reference Standards	Others
Pyraclonil (Standard) is the analytical standard of Pyraclonil. This product is intended for research and analytical applications. Pyraclonil is a proporphyrinogen oxidase (PPO) inhibitor. Pyraclonil is a herbicide agent and is highly effective in controlling the susceptible (S) and multiple-herbicide-resistant (MHR) E. indica populations . Pyraclonil is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-116035R

Nimbolide (Standard)	Wnt NF-κB CDK Apoptosis Reference Standards	Cancer
Nimbolide (Standard) is the analytical standard of Nimbolide. This product is intended for research and analytical applications. Nimbolide is a triterpene compound that can be isolated from neem (Azadirachta indica), possesses anticancer and antiproliferative activity. Nimbolide induces tumor cell apoptosis by inhibiting NF-κB and CDK4/CDK6 kinase. Nimbolide suppresses the Wnt, PI3K-Akt, MAPK and JAK-STAT signaling pathways .

HY-N1465R

Aristolochic acid D (Standard) Aristolochic acid-IVa (Standard)	Reference Standards CDK Phosphodiesterase (PDE) Interleukin Related	Inflammation/Immunology Cancer
Aristolochic acid D (Standard) (Aristolochic acid-IVa (Standard)) is the analytical standard of Aristolochic acid D (HY-N1465). This product is intended for research and analytical applications. Aristolochic acid D (Aristolochic acid-IVa) is an orally active PDE2 (IC₅₀: 4.673 μM) and CDK2 (IC₅₀: 25 μM) inhibitor that can be isolated from Aristolochia indica L. Aristolochic acid D exhibits anti-inflammatory activity and is non-carcinogenic and non-nephrotoxic. Aristolochic acid D can be used in the research of inflammation and tumor-related diseases .

HY-158246

QPP-I-6	Acetyl-CoA Carboxylase	Others
QPP-I-6 is an inhibitor for acetyl-coenzyme A carboxylase (ACCase). QPP-I-6 exhibits herbicidal activity through induction of cell membrane permeability .

HY-N10091

2,3-Dihydro-3α-methoxynimbolide	Apoptosis	Others
2,3-Dihydro-3α-methoxynimbolide is a limonoid compound isolated from the extracts of bark, leaves, roots, and seeds of Azadirachta indica A. Juss. var. siamensis Valeton. 2,3-Dihydro-3α-methoxynimbolide exhibits potent cyto-toxicities against one or more cell lines. 2,3-Dihydro-3α-methoxynimbolide activates caspases-3, -8, and -9, while increases the ratio of Bax/Bcl-2. 2,3-Dihydro-3α-methoxynimbolide induces apoptosis via both mitochondrial and death receptor pathways in AZ521 .

HY-N18754

*Saraca indica* extract**	Bacterial	Metabolic Disease Inflammation/Immunology
Saraca indica extract possesses anti-inflammatory, antioxidant, antibacterial, and antifungal properties; its primary active constituents include flavonoids, saponins, tannins, and alkaloids.

HY-N19057

*Azadirachta indica* extract**	Bacterial	Infection
Azadirachta indica extract contains a variety of bioactive compounds, including azadirachtin, azadirachtin lactone, and azadirachtin, which have antibacterial properties and can effectively combat a variety of bacteria, fungi, and viruses.

HY-N16473

14,15-Epoxyazadiradione	Drug Derivative	Infection Inflammation/Immunology Cancer
14,15-Epoxyazadiradione is a triterpenoid found in Azadirachta indica. Azadirachta indica shows anti-infection, anti-inflammatory and anticancer activities. Azadirachtin H can be used for the researches of cancer, infection and inflammation .

Cat. No.	Product Name		Classification

HY-17531

Pyraclonil		Alkynes
Pyraclonil is a proporphyrinogen oxidase (PPO) inhibitor. Pyraclonil is a herbicide agent and is highly effective in controlling the susceptible (S) and multiple-herbicide-resistant (MHR) E. indica populations . Pyraclonil is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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indica

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