2. Anti-infection
  3. Bacterial
  4. Salannin

Salannin, a limonoid bitter principle of the seed oil of Azadirachta indica, shows antiulcer and spermicidal activities. Salannin displays antibacterial activity towards both Gram-positive and Gram-negative bacteria.

For research use only. We do not sell to patients.

Salannin

Salannin Chemical Structure

CAS No. : 992-20-1

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Based on 1 publication(s) in Google Scholar

Salannin Related Antibodies

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Description

Salannin, a limonoid bitter principle of the seed oil of Azadirachta indica, shows antiulcer and spermicidal activities. Salannin displays antibacterial activity towards both Gram-positive and Gram-negative bacteria[1][2].

In Vivo

Salannin (10, 20, 50 mg/kg; p.o.) shows a significant protective activity on Aspirin (HY-14654) induced gastric lesions[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Wistar rats, weighing 200-220 g (acetyl salicylic acid induced gastric lesions)[2]
Dosage: 10, 20 and 50 mg/kg
Administration: P.o.
Result: Significantly and dose dependently inhibited acetyl salicylic acid-induced gastric lesions.
Molecular Weight

596.71

Formula

C34H44O9
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@]([C@@](O[C@]1([H])C[C@@]2([H])C3=COC=C3)([H])[C@@](OC[C@@]45C)([H])[C@]4([H])[C@@]6([C@H](C[C@H]5OC(C)=O)OC(/C(C)=C/C)=O)C)(C1=C2C)[C@@H]6CC(OC)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 29.94 mg/mL (50.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6759 mL 8.3793 mL 16.7586 mL
5 mM 0.3352 mL 1.6759 mL 3.3517 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.30%

SDS (252 KB)

COA (258 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6759 mL 8.3793 mL 16.7586 mL 41.8964 mL
5 mM 0.3352 mL 1.6759 mL 3.3517 mL 8.3793 mL
10 mM 0.1676 mL 0.8379 mL 1.6759 mL 4.1896 mL
15 mM 0.1117 mL 0.5586 mL 1.1172 mL 2.7931 mL
20 mM 0.0838 mL 0.4190 mL 0.8379 mL 2.0948 mL
25 mM 0.0670 mL 0.3352 mL 0.6703 mL 1.6759 mL
30 mM 0.0559 mL 0.2793 mL 0.5586 mL 1.3965 mL
40 mM 0.0419 mL 0.2095 mL 0.4190 mL 1.0474 mL
50 mM 0.0335 mL 0.1676 mL 0.3352 mL 0.8379 mL
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Salannin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Salannin992-20-1BacterialgastriclesionsantiulcerbacteriaplantspermicidalInhibitorinhibitorinhibit

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