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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
insulin receptor substrate-1
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "insulin receptor substrate-1" in MCE Product Catalog:
1
1 Cited Publications
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NT219 is a potent and dual inhibitor of insulin receptor substrates 1/2 (IRS1/2) and STAT3. IRS1/2 and STAT3 are major signaling junctions regulated by various oncogenes. NT219 affects IRS1/2 degradation and inhibits STAT3 phosphorylation. NT219 has the potential for the research of cancer diseases .
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HNMPA-(AM)3 is a cell-permeable and selective insulin receptor tyrosine kinase inhibitor analog of HNMPA. HNMPA-(AM)3 greatly inhibits the ability of prothoracicotropic hormone (PTTH) to activate ERK phosphorylation and stimulate ecdysteroidogenesis. HNMPA-(AM)3 is also effective in inhibiting ecdysteroid production (IC50=14.2 μM) and insulin receptor activity (IC50 is 14.2 μM and 200 μM in mosquitoes and mammals, respectively) .
Cat. No.: HY-153479
CAS No.: 1146887-67-3
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Aganirsen is a 25 mer DNA antisense oligonucleotide, which silences expression of insulin receptor substrate-1 (IRS-1).
Cat. No.: HY-P5433
CAS No.: 865778-50-3
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MID-1 is a disruptor of MG53-IRS-1 (Mitsugumin 53-insulin receptor substrate-1) interaction. MID-1 disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake .
Category:
Infection other families Ketones, Aldehydes, Acids Phenols Polyphenols Plants Disease Research Fields
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Cat. No.: HY-P1790
CAS No.: 143364-95-8
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Cat. No.: HY-153479A
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Aganirsen sodium is a 25 mer DNA antisense oligonucleotide, which silences expression of insulin receptor substrate-1 (IRS-1).
Cat. No.: HY-P702944
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IRS1; HIRS-1; insulin receptor substrate 1; IRS-1
Species:
Human
Source:
E. coli
Cat. No.: HY-P703573
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IRS1; HIRS-1; insulin receptor substrate 1; IRS-1
Species:
Human
Source:
E. coli
Cat. No.: HY-P1776
CAS No.: 141171-54-2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
