1198078-60-2
Chemical Structure
NT219
- CAS No.: 1198078-60-2
- Formula:C16H14BrNO5S
- Molecular Weight:412.26
IUPAC Name: (E)-3-(2-bromo-3,4-dihydroxyphenyl)-N-(3,4,5-trihydroxybenzyl)prop-2-enethioamide
InChIKey: XDDQKKXXQHUUHJ-DUXPYHPUSA-N
SMILES: OC(C=C1CNC(/C=C/C2=C(C(O)=C(C=C2)O)Br)=S)=C(C(O)=C1)O
Biological Activity: NT219 is a potent and dual inhibitor of insulin receptor substrates 1/2 (IRS1/2) and STAT3. IRS1/2 and STAT3 are major signaling junctions regulated by various oncogenes. NT219 affects IRS1/2 degradation and inhibits STAT3 phosphorylation. NT219 has the potential for the research of cancer diseases[1].
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NT219 | 98.57% | NT219 is a potent and dual inhibitor of insulin receptor substrates 1/2 (IRS1/2) and STAT3. IRS1/2 and STAT3 are major signaling junctions regulated by various oncogenes. NT219 affects IRS1/2 degradation and inhibits STAT3 phosphorylation. NT219 has the potential for the research of cancer diseases. | ||||||||||||||||||||
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Keywords
