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Results for "

interleukin-2 receptor alpha (CD25)

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Interleukin Related (4) Apoptosis (1)
By Research Areas:	Cancer (2) Inflammation/Immunology (3) Metabolic Disease (1)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Targets Recommended:

5 alpha Reductase
IFNAR
Itk
Interleukin Related
IRAK
CD1
CD38
CD28
CD19
CD20
CD22
Transferrin Receptor
CD3
P-selectin
CD6
CD2
CD276/B7-H3
CD73
c-Kit
LAG-3
L-Selectin
CTLA-4
CD47
ALCAM/CD166
Neprilysin
E-Selectin
Scavenger Receptor Class B type I (SR-BI）
FLT3
Tim3
CD44
Anaplastic lymphoma kinase (ALK)
CD74
Human leukocyte immunoglobulin (Ig)-like receptors (LILR)
P-glycoprotein

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-108738

Daclizumab Ro 24-7375	Interleukin Related Apoptosis	Inflammation/Immunology Cancer
Daclizumab (Ro 24-7375) is a humanized, monoclonal antibody that blocks *CD25* (α-subunit of the high-affinity interleukin-2 receptor (IL-2R-HA)). Daclizumab inhibits effector T cell activation, regulatory T cell (Treg) expansion and survival, and activation-induced T-cell apoptosis. Daclizumab increases IL-2 bioavailability to bind to the intermediate-affinity IL-2R (IL-2R-IA), driving the expansion of anti-inflammatory CD56bright natural killer (NK) cells. Daclizumab can be used for multiple sclerosis and cancer research .

HY-P99728

Melredableukin alfa RG7835; RO7049665	Interleukin Related	Metabolic Disease Inflammation/Immunology
Melredableukin alfa (RG7835) is a bivalent conjugate composed of a human IL-2 mutant (T3A, N88D, C125A) and human IgG1. Melredableukin alfa exhibits enhanced Treg cell selectivity in cynomolgus monkey and humanized mouse models. Melredableukin alfa can be used in research related to ulcerative colitis and autoimmune hepatitis .

HY-P990086

Vopikitug RG-6292; RO-7296682	Interleukin Related	Cancer
Vopikitug is an IgG1-kappa, anti-IL2RA (interleukin 2 receptor alpha subunit, IL-2RA, TAC, p55, CD25) homo sapiens monoclonal antibody. Vopikitug shows antineoplastic activity .

HY-P991749

Anti-Rat CD25 Antibody (OX-39)	Interleukin Related	Inflammation/Immunology
Anti-Rat CD25 Antibody (OX-39) recognizes the 55 kDa low-affinity **interleukin-2 receptor α chain (IL-2R α, CD25)*. Anti-Rat CD25* Antibody (OX-39) interacts with a single class of sites on the alpha chain of the rat R-IL2 with a high affinity (K_d of 0.8 nM) and competes with IL2 binding on this chain (K_i of 0.53 nM). Anti-Rat CD25 Antibody (OX-39) is a weak inhibitor in vitro on IL2-induced proliferation and in vivo on allograft rejection. Recommend Isotype Controls: Mouse IgG1 kappa, Isotype Control (HY-P99977) .

Cat. No.	Product Name	Target	Research Area	Image

HY-108738

Daclizumab Ro 24-7375	Interleukin Related Apoptosis	Inflammation/Immunology Cancer
Daclizumab (Ro 24-7375) is a humanized, monoclonal antibody that blocks *CD25* (α-subunit of the high-affinity interleukin-2 receptor (IL-2R-HA)). Daclizumab inhibits effector T cell activation, regulatory T cell (Treg) expansion and survival, and activation-induced T-cell apoptosis. Daclizumab increases IL-2 bioavailability to bind to the intermediate-affinity IL-2R (IL-2R-IA), driving the expansion of anti-inflammatory CD56bright natural killer (NK) cells. Daclizumab can be used for multiple sclerosis and cancer research .

HY-P99728

Melredableukin alfa RG7835; RO7049665	Interleukin Related	Metabolic Disease Inflammation/Immunology
Melredableukin alfa (RG7835) is a bivalent conjugate composed of a human IL-2 mutant (T3A, N88D, C125A) and human IgG1. Melredableukin alfa exhibits enhanced Treg cell selectivity in cynomolgus monkey and humanized mouse models. Melredableukin alfa can be used in research related to ulcerative colitis and autoimmune hepatitis .

HY-P990086

Vopikitug RG-6292; RO-7296682	Interleukin Related	Cancer
Vopikitug is an IgG1-kappa, anti-IL2RA (interleukin 2 receptor alpha subunit, IL-2RA, TAC, p55, CD25) homo sapiens monoclonal antibody. Vopikitug shows antineoplastic activity .

HY-P991749

Anti-Rat CD25 Antibody (OX-39)	Interleukin Related	Inflammation/Immunology
Anti-Rat CD25 Antibody (OX-39) recognizes the 55 kDa low-affinity **interleukin-2 receptor α chain (IL-2R α, CD25)*. Anti-Rat CD25* Antibody (OX-39) interacts with a single class of sites on the alpha chain of the rat R-IL2 with a high affinity (K_d of 0.8 nM) and competes with IL2 binding on this chain (K_i of 0.53 nM). Anti-Rat CD25 Antibody (OX-39) is a weak inhibitor in vitro on IL2-induced proliferation and in vivo on allograft rejection. Recommend Isotype Controls: Mouse IgG1 kappa, Isotype Control (HY-P99977) .

Species:	Human (1) Rhesus Macaque (1) Rat (1) Mouse (2) Cynomolgus (5)
Tag:	His (7) Tag Free (1) Avi (2) Fc (2)
Source:	HEK293 (9) Sf9 insect cells (1)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P76785

	IL-2R alpha/CD25 Protein, Cynomolgus (HEK293) CD25; IDDM10; IL-2 R alpha; IL2-RA; interleukin 2 receptor, alpha; TCGFR	Cynomolgus	HEK293
	IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions. IL-2R alpha/CD25 Protein, Cynomolgus (HEK293) is a recombinant cynomolgus IL-2R alpha protein and is expressed in HEK293 cells. It consists of 213 amino acids (M1-R213).

HY-P72550

	IL-2R alpha/CD25 Protein, Mouse (HEK293, His) interleukin-2 receptor subunit alpha; IL-2-RA; CD25; TCGFR; p55	Mouse	HEK293
	IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions.IL-2R alpha/CD25 Protein, Mouse (HEK293, His) is a recombinant mouse IL-2R alpha protein with a His tag at the C-terminus and is expressed in HEK293 cells.

HY-P74809

	IL-2R alpha/CD25 Protein, Rat (sf9, His) CD25; IDDM10; IL-2 R alpha; IL2-RA; interleukin 2 receptor, alpha; TCGFR	Rat	Sf9 insect cells
	IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions. IL-2R alpha/CD25 Protein, Rat (sf9, His) is a recombinant rat IL-2R alpha protein with a His tag at the C-terminus and is expressed in Sf9 insect cells.

HY-P74811

	IL-2R alpha/CD25 Protein, Mouse (HEK293, hFc) CD25; IDDM10; IL-2 R alpha; IL2-RA; interleukin 2 receptor, alpha; TCGFR	Mouse	HEK293
	IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions. IL-2R alpha/CD25 Protein, Mouse (HEK293, hFc) is a recombinant mouse IL-2R alpha protein with an hFc tag at the C-terminus and is expressed in HEK293 cells.

HY-P76786

	IL-2R alpha/CD25 Protein, Cynomolgus (HEK293, Fc) CD25; IDDM10; IL-2 R alpha; IL2-RA; interleukin 2 receptor, alpha; TCGFR	Cynomolgus	HEK293
	IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions. IL-2R alpha/CD25 Protein, Cynomolgus (HEK293, Fc) is a recombinant cynomolgus IL-2R alpha protein with an hFc tag at the C-terminus and is expressed in HEK293 cells. It consists of 213 amino acids (M1-R213).

HY-P76787

	IL-2R alpha/CD25 Protein, Cynomolgus (HEK293, His) CD25; IDDM10; IL-2 R alpha; IL2-RA; interleukin 2 receptor, alpha; TCGFR	Cynomolgus	HEK293
	IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions. IL-2R alpha/CD25 Protein, Cynomolgus (HEK293, His) is a recombinant cynomolgus IL-2R alpha protein with a His tag at the C-terminus and is expressed in HEK293 cells. It consists of 213 amino acids (M1-R213).

HY-P703846

	IL-2R alpha/CD25 Protein, Cynomolgus (Biotinylated, HEK293, His, Avi) CD25; IDDM10; IL-2 R alpha; IL2-RA; interleukin 2 receptor, alpha; TCGFR	Cynomolgus	HEK293
	IL-2R alpha/CD25 Protein, Cynomolgus (Biotinylated, HEK293, His, Avi) is the recombinant cynomolgus-derived IL-2R alpha/CD25 protein, expressed by HEK293, with C-His & Avi tag.

HY-P75629

	IL-2R alpha/CD25 Protein, Rhesus Macaque (Biotinylated, HEK293, His-Avi) CD25; IDDM10; IL-2 R alpha; IL2-RA; interleukin 2 receptor, alpha; TCGFR	Rhesus Macaque	HEK293
	IL-2R alpha (CD25) is an essential component of high-affinity IL-2 receptors. IL-2R alpha enhances binding of IL-2 to its receptor complex so that regulates T cell growth and other lymphoid functions. IL-2R alpha/CD25 Protein, Rhesus Macaque (Biotinylated, HEK293, His-Avi) is a recombinant rhesus macaque IL-2R alpha protein with a His tag and an Avi tag at the C-terminus and is expressed in HEK293 cells. It consists of 213 amino acids (M1-R213) and is biotinylated.

HY-P704702

	IL-2R alpha/CD25 Protein, Cynomolgus (217a.a, HEK293, His) CD25; IDDM10; IL-2 R alpha; IL2-RA; interleukin 2 receptor, alpha; TCGFR	Cynomolgus	HEK293
	IL-2R alpha/CD25 Protein, Cynomolgus (217a.a, HEK293, His) is the recombinant cynomolgus-derived IL-2R alpha/CD25 protein, expressed by HEK293, with C-His tag.

HY-P70628

	IL-2R alpha/CD25 Protein, Human (HEK293, C-His) IL-2R alpha; IL-2RA; interleukin-2 receptor subunit alpha; CD25; p55; TAC antigen; IL2-RA; IL-2R subunit alpha; IL-2-RA; IL-2 receptor subunit alpha	Human	HEK293
	IL-2R alpha protein is the receptor for interleukin 2 and plays a crucial role in immune tolerance by regulating the activity of regulatory T cells (TREG). These TREGs are responsible for inhibiting the activation and expansion of autoreactive T cells.IL-2R alpha/CD25 Protein, Human (HEK293, C-His) is the recombinant human-derived IL-2R alpha protein, expressed by HEK293 , with C-6*His labeled tag.

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Accession
Gene ID
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Host:	Mouse (2) Rabbit (2)
Reactivity:	Human (4)
Application:	IHC-P (2) ICC/IF (2) FC (1) ELISA (2)
Isotype:	IgG (2)
Conjugation:	Non-conjugated (4) Biotin (2)
Clonality:	Monoclonal (4) Recombinant (2)
Modification:	Unmodified (4)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P84978

	CD25 Antibody (YA4670) IL2RA; interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; TAC antigen; p55; CD25; CD25 nanobody;	ELISA	Human
	CD25 Antibody (YA4670) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD25.

HY-P85676

	CD25 Antibody (YA5368) IL2RA; interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; TAC antigen; p55; CD25	IHC-P, ICC/IF	Human
	CD25 Antibody (YA5368) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD25.

HY-P81712

	IL-2 Receptor alpha Antibody (YA1457) IL2RA; interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; TAC antigen; p55; CD25	FC, ELISA	Human
	IL-2 Receptor alpha Antibody (YA1457) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-2 Receptor alpha.

HY-P82616

	IL-2 Receptor alpha Antibody (YA2361) IL2RA; interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; TAC antigen; p55; CD25	IHC-P, ICC/IF	Human
	IL-2 Receptor alpha Antibody (YA2361) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-2 Receptor alpha.

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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

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