2. Protéines recombinantes
  3. Receptor Proteins Others
  4. Cytokine Receptors
  5. IL-2R alpha/CD25 Protein, Cynomolgus (Biotinylated, HEK293, His, Avi)

IL-2R alpha/CD25 Protein, Cynomolgus (Biotinylated, HEK293, His, Avi)

Cat. No.: HY-P703846
Instruction de manipulation Technical Support

IL-2R alpha/CD25 Protein, Cynomolgus (Biotinylated, HEK293, His, Avi) is the recombinant cynomolgus-derived IL-2R alpha/CD25 protein, expressed by HEK293, with C-His & Avi tag.

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Description

IL-2R alpha/CD25 Protein, Cynomolgus (Biotinylated, HEK293, His, Avi) is the recombinant cynomolgus-derived IL-2R alpha/CD25 protein, expressed by HEK293, with C-His & Avi tag.
Background

IL-2R alpha/CD25 is a receptor for interleukin-2, involved in regulating immune tolerance by controlling the activity of regulatory T cells (TREGs). TREGs suppress the activation and expansion of autoreactive T-cells.
Species

Cynomolgus
Source

HEK293
Tag

C-His;Avi
Accession

H6WS54 (E22-R213)
Gene ID

102123605
Protein Length

Partial
Conjugation

Biotin
Synonyms
CD25; IDDM10; IL-2 R alpha; IL2-RA; Interleukin 2 receptor, alpha; TCGFR
AA Sequence

ELCDDDPPKITHATFKAVAYKEGTMLNCECKRGFRRIKSGSPYMLCTGNSSHSSWDNQCQCTSSAARNTTKQVTPQPEEQKERKTTEMQSQMQLADQVSLPGHCREPPPWENEATERIYHFVVGQTVYYQCVQGYRALHRGPAESVCKMTHGKTRWTQPQLICTGETEPSQFPGEEEPQASPDGLPESETSR

Predicted Molecular Mass
24.9 kDa
Masse moléculaire

Approximately 44 kDa, based on SDS-PAGE under reducing conditions.
Pureté

≥ 95%, as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Instruction de manipulation (2659 KB)

IL-2R alpha/CD25 Protein, Cynomolgus (Biotinylated, HEK293, His, Avi) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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IL-2R alpha/CD25 Protein, Cynomolgus (Biotinylated, HEK293, His, Avi)
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