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Results for "

lysophospholipid

" in MedChemExpress (MCE) Product Catalog:

By Targets:	LPL Receptor (2) Acyltransferase (1) Drug Metabolite (1) Endogenous Metabolite (8) GPR55 (1) Isotope-Labeled Compounds (3) Liposome (2) Phosphodiesterase (PDE) (1) Phospholipase (1)
By Research Areas:	Cancer (1) Infection (1) Inflammation/Immunology (3) Metabolic Disease (8) Neurological Disease (4)

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Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: LPL Receptor

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W020035

L-α-lysophosphatidylinositol (Soy) (sodium)	GPR55	Neurological Disease
L-α-lysophosphatidylinositol Soy sodium is an endogenous ligand of GPR55. L-α-lysophosphatidylinositol Soy sodium is an endogenous lysophospholipid and endocannabinoid neurotransmitter that belongs to the class of lysophospholipids .

HY-113123

LysoPC(14:0/0:0) 14:0 Lyso PC; 1-myristoyl-sn-glycero-3-phosphatidylcholine	Endogenous Metabolite	Neurological Disease Metabolic Disease
LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. LysoPC(14:0/0:0) has potent antispasmodic effect .

HY-N9410

Lysophosphatidylcholine 18:2 1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC	Endogenous Metabolite	Metabolic Disease
Lysophosphatidylcholine 18:2 (1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC), a lysophospholipid, is a potential biomarker identified from insulin resistance (IR) polycystic ovary syndrome (PCOS). Low plasma Lysophosphatidylcholine 18:2 also has been shown to predict impaired glucose tolerance, insulin resistance, type 2 diabetes, coronary artery disease, and memory impairment .

HY-143864

S1PR1 agonist 1	LPL Receptor	Inflammation/Immunology
S1PR1 agonist 1 is a potent agonist of S1PR1. Sphingosine-1-phosphate (S1P) is a cell membrane-derived lysophospholipid signalling molecule that exerts its physiological functions mainly by stimulating some members of the G protein-coupled receptor family. S1PR1 agonist 1 has the potential for the research of autoimmune diseases (extracted from patent WO2021175223A1, compound 22) .

HY-143865

S1PR1 agonist 2	LPL Receptor	Inflammation/Immunology
S1PR1 agonist 2 is a potent agonist of S1PR1. Sphingosine-1-phosphate (S1P) is a cell membrane-derived lysophospholipid signalling molecule that exerts its physiological functions mainly by stimulating some members of the G protein-coupled receptor family. S1PR1 agonist 2 has the potential for the research of autoimmune diseases (extracted from patent WO2021175225A1, compound 1) .

HY-113010

1-Arachidoyl-sn-glycero-3-phosphocholine

Endogenous Metabolite Others

1-Arachidoyl-sn-glycero-3-phosphocholine is a lysophospholipid (LyP).
HY-103660

18:0 LYSO-PE

Liposome Neurological Disease

18:0 LYSO-PE is a lysophospholipid that can induce [Ca ²⁺]_i increase.
HY-138622

24:0 Lyso PC

Liposome Others

24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery .

1-Arachidoyl-sn-glycero-3-phosphocholine	Endogenous Metabolite	Others
1-Arachidoyl-sn-glycero-3-phosphocholine is a lysophospholipid (LyP).

*18:0 LYSO-PE*	Liposome	Neurological Disease
18:0 LYSO-PE is a lysophospholipid that can induce [Ca ²⁺]_i increase.

*24:0 Lyso* PC**	Liposome	Others
24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery .

HY-E70259

18:2 (n6) Coenzyme A triammonium	Endogenous Metabolite	Metabolic Disease
18:2 (n6) Coenzyme A triammonium is a Coenzyme A. 18:2 (n6) Coenzyme A triammonium can be used to determine the effects of lysophospholipid acyltransferase activities in adipocyte differentiation .

HY-W704966

2-Stearoyl-sn-glycero-3-phosphocholine 18:0 Lyso-PC; LPC(18:0); PC(0:0/18:0)	Endogenous Metabolite	Metabolic Disease
2-Stearoyl-sn-glycero-3-PC is a lysophospholipid that contains stearic acid (HY-B2219) at the sn-2 position. It has been found in rabbit myocardium.

HY-138622S1

*24:0 Lyso* PC-d4**	Isotope-Labeled Compounds	Others
24:0 Lyso PC-d₄4 is the deuterium labeled 24:0 Lyso PC. 24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery[1].

HY-138622S

*24:0 Lyso* PC-13C6**	Isotope-Labeled Compounds	Others
24:0 Lyso PC- ¹³C₆ is the ¹³C labeled 24:0 Lyso PC. 24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery[1].

HY-E70251

22:6 Coenzyme A Docosahexaenoyl coenzyme A triammonium	Others	Others
22:6 Coenzyme A (Docosahexaenoyl coenzyme A triammonium) is a coenzyme that contains 22 carbon atoms and 6 unsaturated bonds. 22:6 Coenzyme A can serve as an acyl substrate and is used in research on the effects of lysophospholipid acyltransferase activities in adipocyte differentiation .

HY-113010S1

1-Arachidoyl-sn-glycero-3-phosphocholine-d4	Endogenous Metabolite	Others
1-Arachidoyl-sn-glycero-3-phosphocholine-d₄4 is the deuterium labeled 1-Arachidoyl-sn-glycero-3-phosphocholine. 1-Arachidoyl-sn-glycero-3-phosphocholine is a lysophospholipid (LyP).

HY-W355700

1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine	Drug Metabolite	Infection
1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine. It is the main degradation product of deltamethrin metabolized by the prokaryotic protein (CYP6A14 and CYP6N6) complexes in vitro .

HY-12812

Autotaxin modulator 1	Phosphodiesterase (PDE)	Neurological Disease Cancer
Autotaxin modulator 1 is an autotaxin (ATX) enzyme inhibitor, extracted from patent WO 2014018881 A1, Compound Example 12b. Autotaxin modulator 1 is expected to be useful for researching demyelination due to injury or disease, as well as for researching proliferative disorders such as cancer .

HY-N9410S

Lysophosphatidylcholine 18:2-d9 1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC-d₉	Isotope-Labeled Compounds Endogenous Metabolite	Metabolic Disease
Lysophosphatidylcholine 18:2-d₉ is deuterium labeled Lysophosphatidylcholine 18:2. Lysophosphatidylcholine 18:2 (1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC), a lysophospholipid, is a potential biomarker identified from insulin resistance (IR) polycystic ovary

HY-107572

PD 128042 CI 976	Acyltransferase	Metabolic Disease
PD 128042 (CI 976) is a potent, orally active, and selective inhibitor of ACAT (acyl coenzyme A:cholesterol acyltransferase) with an IC₅₀s of 73 nM. PD 128042 is also a potent LPAT (lysophospholipid acyltransferase) inhibitor. PD 128042 inhibits Golgi-associated LPAT activity (IC₅₀=15 μM). PD 128042 inhibits multiple membrane trafficking steps, including ones found in the endocytic and secretory pathway .

HY-145384

ROC-0929	Phospholipase	Inflammation/Immunology
ROC-0929 (compound 13a) is a potent and selective inhibitor of secreted phospholipases A₂ (sPLA₂s) with an IC₅₀ of 80 nM, specially targeting hGX. ROC-0929 inhibits the phosphorylation of ERK1/2 and p-38. Secreted phospholipases A2 (sPLA2s) are a family of disulfide-rich, Ca ²⁺-dependent enzymes that hydrolyze the sn-2 position of glycero-phospholipids to release a fatty acid and a lysophospholipid. ROC-0929 has the potential for researching inflammation related diseases .

HY-156041

Lysophosphatidylethanolamines, egg Lyso-PE (egg); LPE (egg); L-α-lysophosphatidylethanolamine	Endogenous Metabolite	Metabolic Disease
Lysophosphatidylethanolamine (LPE) is a naturally-occurring lysophospholipid that can be generated via deacylation of phosphatidylethanolamine by phospholipase A2 (PLA2). It increases the phosphorylation of ERK1/2 in PC12 cells, an effect that can be blocked by the MEK inhibitors U-0126 (HY-12031A) and PD 98059 (HY-12028) and the EGFR inhibitor AG-1478 (HY-13524).1 LPE also increases neurite outgrowth and expression of neurofilament M in PC12 cells. LPE inhibits the activity of phospholipase D (PLD) partially purified from cabbage.3 This product contains lysophosphatidylethanolamine molecular species with variable fatty acyl chain lengths at the sn-1 position and a hydroxy group at the sn-2 position.

*24:0 Lyso* PC**	Drug Delivery
24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery .

sPLA2-IIA Inhibitor	Peptides	Metabolic Disease
sPLA2-IIA Inhibitor is a cyclic pentapeptide analog of FLSYK (cyclic 2-Nal-Leu-Ser-2-Nal-Arg (c2)), that binds to hGIIA (human IIA phospholipase A2) and inhibits its hydrolytic ability. sPLA2 is a member of the esterase superfamily that catalyzes the hydrolysis of the ester bond at the sn-2 position of glycerophospholipids, releasing free fatty acids such as arachidonic acid and lysophospholipids .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-113123

LysoPC(14:0/0:0) 14:0 Lyso PC; 1-myristoyl-sn-glycero-3-phosphatidylcholine	Structural Classification Natural Products Microorganisms Source classification Endogenous metabolite	Endogenous Metabolite
LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. LysoPC(14:0/0:0) has potent antispasmodic effect .

HY-N9410

Lysophosphatidylcholine 18:2 1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC	Infection Natural Products Classification of Application Fields Source classification Disease markers Metabolic Disease Endocrine diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Lysophosphatidylcholine 18:2 (1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC), a lysophospholipid, is a potential biomarker identified from insulin resistance (IR) polycystic ovary syndrome (PCOS). Low plasma Lysophosphatidylcholine 18:2 also has been shown to predict impaired glucose tolerance, insulin resistance, type 2 diabetes, coronary artery disease, and memory impairment .

HY-113010

1-Arachidoyl-sn-glycero-3-phosphocholine	Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
1-Arachidoyl-sn-glycero-3-phosphocholine is a lysophospholipid (LyP).

Cat. No.	Product Name	Chemical Structure

HY-138622S1

24:0 Lyso PC-d4

24:0 Lyso PC-d₄4 is the deuterium labeled 24:0 Lyso PC. 24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery[1].
HY-138622S

24:0 Lyso PC-13C6

24:0 Lyso PC- ¹³C₆ is the ¹³C labeled 24:0 Lyso PC. 24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery[1].

*24:0 Lyso* PC-d4**
24:0 Lyso PC-d₄4 is the deuterium labeled 24:0 Lyso PC. 24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery[1].

*24:0 Lyso* PC-13C6**
24:0 Lyso PC- ¹³C₆ is the ¹³C labeled 24:0 Lyso PC. 24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery[1].

HY-113010S1

1-Arachidoyl-sn-glycero-3-phosphocholine-d4
1-Arachidoyl-sn-glycero-3-phosphocholine-d₄4 is the deuterium labeled 1-Arachidoyl-sn-glycero-3-phosphocholine. 1-Arachidoyl-sn-glycero-3-phosphocholine is a lysophospholipid (LyP).

HY-N9410S

Lysophosphatidylcholine 18:2-d9
Lysophosphatidylcholine 18:2-d₉ is deuterium labeled Lysophosphatidylcholine 18:2. Lysophosphatidylcholine 18:2 (1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC), a lysophospholipid, is a potential biomarker identified from insulin resistance (IR) polycystic ovary

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lysophospholipid

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Natural
Products