89576-29-4
Chemical Structure
1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine
- CAS No.: 89576-29-4
- Formula:C23H46NO7P
- Molecular Weight:479.59
IUPAC Name: (2R)-3-(((2-aminoethoxy)(hydroxy)phosphoryl)oxy)-2-hydroxypropyl oleate
InChIKey: PYVRVRFVLRNJLY-MZMPXXGTSA-N
SMILES: CCCCCCCC/C=C\CCCCCCCC(OC[C@@H](O)COP(OCCN)(O)=O)=O
Biological Activity: 1-oleoyl-sn-glycero-3-phosphoethanolamine (LysoPE 18:1) is a lysophosphatidylethanolamine molecule involved in phospholipid metabolism, targeting cell membrane receptors (such as G protein-coupled receptors) to regulate cell signaling pathways. 1-oleoyl-sn-glycero-3-phosphoethanolamine may activate mitogen-activated protein kinase (MAPK) signaling, promote cell migration, regulate inflammatory responses and lipid metabolism, and has both pro-inflammatory and anti-inflammatory activities. 1-oleoyl-sn-glycero-3-phosphoethanolamine is mainly used in the screening of biomarkers for metabolic diseases (such as non-alcoholic fatty liver disease and obesity), as well as the study of the mechanism of lysophospholipids in cell membrane homeostasis and signal transduction[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine | 98.95% | 1-oleoyl-sn-glycero-3-phosphoethanolamine (LysoPE 18:1) is a lysophosphatidylethanolamine molecule involved in phospholipid metabolism, targeting cell membrane receptors (such as G protein-coupled receptors) to regulate cell signaling pathways. 1-oleoyl-sn-glycero-3-phosphoethanolamine may activate mitogen-activated protein kinase (MAPK) signaling, promote cell migration, regulate inflammatory responses and lipid metabolism, and has both pro-inflammatory and anti-inflammatory activities. 1-oleoyl-sn-glycero-3-phosphoethanolamine is mainly used in the screening of biomarkers for metabolic diseases (such as non-alcoholic fatty liver disease and obesity), as well as the study of the mechanism of lysophospholipids in cell membrane homeostasis and signal transduction. | ||||||||||||||||||||
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1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine-d31 | 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine-d31 is the deuterium labeled 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (HY-W355700). 1-oleoyl-sn-glycero-3-phosphoethanolamine (LysoPE 18:1) is a lysophosphatidylethanolamine molecule involved in phospholipid metabolism, targeting cell membrane receptors (such as G protein-coupled receptors) to regulate cell signaling pathways. 1-oleoyl-sn-glycero-3-phosphoethanolamine may activate mitogen-activated protein kinase (MAPK) signaling, promote cell migration, regulate inflammatory responses and lipid metabolism, and has both pro-inflammatory and anti-inflammatory activities. 1-oleoyl-sn-glycero-3-phosphoethanolamine is mainly used in the screening of biomarkers for metabolic diseases (such as non-alcoholic fatty liver disease and obesity), as well as the study of the mechanism of lysophospholipids in cell membrane homeostasis and signal transduction. | |||||||||||||||||||||
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1-Oleoyl-2-hydroxy-sn-glycero-3-phosphatidylethanolamine-d7 | 99.0% | 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphatidylethanolamine-d7 is deuterium labeled 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphatidylethanolamine. | ||||||||||||||||||||
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- [1]. Yamamoto Y, et al. Analysis of serum lysophosphatidylethanolamine levels in patients with non-alcoholic fatty liver disease by liquid chromatography-tandem mass spectrometry. Anal Bioanal Chem. 2021 Jan;413(1):245-254. [Content Brief]
- [2]. Inoue N, et al. Determination of plasma lysophosphatidylethanolamines (lyso-PE) by LC-MS/MS revealed a possible relation between obesity and lyso-PE in Japanese preadolescent children: The Hokkaido study. Ann Clin Biochem. 2025 Jan;62(1):34-45. [Content Brief]
