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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
37 Results for "
mRNA drug delivery
" in MedChemExpress (MCE) Product Catalog:
Products (37)
37 Results for "mRNA drug delivery" in MCE Product Catalog:
1
1-Palmitoyl-2-oleoyl-sn-glycero-3-PE (1,2-POPE; 16:0-18:1 PE) is a phosphatidylethanolamine (PE) lipid. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can induce lipid bilayer to form a hexagonal phase (HII) structure in an acidic environment and promote membrane fusion. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can enhance the endosomal escape ability of lipid nanoparticles (LNPs) and improve the cellular delivery efficiency of nucleic acid drugs such as mRNA. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PE can be used for LNP carrier targeting of gene therapy and mRNA vaccines .
Cat. No.: HY-171306
MK16 is a lipid material that can be used to construct blood-brain barrier penetrable lipid nanoparticles for mRNA delivery. MK16 facilitates blood-brain barrier crossing via γ-secretase-mediated and caveolae-mediated transcytosis. MK16 can be used for drug delivery research .
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6-Oxohexyl 2-hexyldecanoate, 80% (ELSD) is an intermediate in the synthesis of ALC-0315. 6-Oxohexyl 2-hexyldecanoate, 80% (ELSD) can be used in research on drug delivery, such as mRNA delivery .
Cat. No.: HY-W440896
DSPE-PEG2000-SH is an amphiphilic thiol-functionalized DSPE-PEG molecule. DSPE-PEG2000-SH inserts into extracellular vesicle (EV) bilayer membranes via hydrophobic interactions, displaying surface thiol groups to form EV-SH crosslinkers.DSPE-PEG2000-SH enables crosslinking of EV-SH with 8-arm PEG-norbornene via thiol-ene photochemistry to construct hydrogels, with hydrogel mechanical properties tunable via PEG segment molecular weight variation.DSPE-PEG2000-SH can be used to encapsulate agents for drug delivery system, such as mRNA vaccine .
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TriGalNAc CBz is a GalNAc derivative and tri-GalNAc is an asialoglycoprotein receptor (ASGPR) ligand. TriGalNAc CBz can be used for mRNA drug delivery as well as lysosomal targeted chimerism (LYTAC) studies .
24:0 Lyso PC is a lysophospholipid (LyP). 24:0 Lyso PC could be used for mRNA drug delivery .
Cat. No.: HY-W441015A
DSPE-m-PEG3400-NHS is a pegylated phospholipid derivatives which can be used to prepare liposome or lipid nanoparticles for targeted drug delivery system, such as DNA or mRNA vaccine .
Cat. No.: HY-W440895
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DSPE-PEG1000-SH is an amphiphilic poly-PEG that can form lipid bilayers in water. This amphiphilic polymer can form lipid bilayers in aqueous solution and can be used to embed active molecules for drug delivery systems such as mRNA vaccines.
Cat. No.: HY-P3402
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Cat. No.: HY-P3402A
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Cat. No.: HY-186041
CAS No.: 3109642-25-0
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E12LA6B6O3 is an amino lipid that can be used to prepare nanoparticles for drug delivery, such as mRNA .
Cat. No.: HY-W440899
DSPE-PEG1000-SPDP is a thiol reactive PEG lipid. The polymer is amphiphilic and spontaneously forms lipid bilayer in water. It can be used to encapsulate nutrients or therapeutics for targeted drug delivery, for example mRNA or DNA vaccine, liposomal doxorubicin for anti tumor.
Cat. No.: HY-176512
CAS No.: 3100308-37-7
FO-32 is an ionizable lipid and mRNA delivery carrier with state-of-the-art aerosolized mRNA delivery capability. FO-32 delivers mRNA to mouse muscle, nasal mucosa, lung, as well as ferret lung epithelium (including conducting airways). FO-32 can be used in studies related to the generation of lipid nanoparticles (LNPs) and the optimization of drug delivery .
Cat. No.: HY-W441003
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DSPE-PEG2000-IA is a thiol reactive phospholipid polyPEG. The iodoacetyll group is reactive with thiol to produce a thioether linkage. The polymer can self-assemble in water to form lipid bilayer and can be used to encapsulate drugs in targeted delivery application, such as liposomal doxorubicin as an anti cancer drug or mRNA vaccine.
Cat. No.: HY-W440883
DSPE-PEG2000-Ald is a phospholipid polyPEG which can self-assemble to form lipid bilayer in aqueous solution. The polymer can be used to prepare liposome as a drug delivery vehicle for administration of drugs or nutrients, such as mRNA vaccines. The aldehyde is reactive with aminooxy to form a stable oxime linkage or with amine at pH < 7 to form a reversible imine bond. Reagent grade, for research use only.
Cat. No.: HY-W440904
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DSPE-PEG1000-Vinylsulfone is a viniyl sulfone PEG lipid which can be used for bioconjugation with cysteine or other thiol molecule through thiol-ene reaction. The polymer is a self-assembling reagetn which forms lipid bilayer in water and can be used as drug carrier to delivery therapeutic agents, such as mRNA or DNA vaccine.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
