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mesoporous silica nanoparticles

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Biochemical Assay Reagents (3) RUNX (1) TGF-beta/Smad (1)
By Research Areas:	Cancer (2) Metabolic Disease (1)
Click Chemistry:	DBCO (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W243303J

Poly(acrylic acid) (MW 250000)	Biochemical Assay Reagents	Cancer
Poly(acrylic acid) (MW 250000) is a synthetic cationic electrolyte containing abundant carboxyl groups (-COOH), which exhibits excellent water absorption and retention properties and is often cross-linked to form hydrogels. Poly(acrylic acid) (with a molecular weight of 250,000). Poly(acrylic acid) (MW 250000) can be used as a non-collagenous analog in the biomimetic mineralization research of type I collagen. Poly(acrylic acid) (MW 250000) has pH responsiveness and biocompatibility and is often used as a drug carrier, surface modifier and functional material .

HY-P5832

BMP2-derived peptide	TGF-beta/Smad RUNX	Metabolic Disease
BMP2-derived peptide is an osteogenic inducer and BMP receptor ligand. BMP2-derived peptide binds to BMP receptors on the cell surface to form a complex, activates the downstream Smad signaling pathway, and regulates the expression of osteogenic transcription factors. BMP2-derived peptide effectively promotes the adhesion, proliferation, osteogenic differentiation and mineralization of bone marrow mesenchymal stem cells, significantly up-regulates the mRNA levels of OCN, Runx2 and type I collagen, and increases alkaline phosphatase activity and calcium deposition. BMP2-derived peptide induces osteoblast differentiation and ectopic bone regeneration, and improves cranial bone defect repair. Meanwhile, BMP2-derived peptide enhances the cytocompatibility of mesoporous silica nanoparticles, synergistically increases osteogenic activity with Dexamethasone (HY-14648), serving as an important tool for bone defect repair research .

HY-174929A

DBCO-PEG5000-Amine DBCO-PEG5000-NH2	Biochemical Assay Reagents	Others
DBCO-PEG5000-Amine (DBCO-PEG5000-NH2) is a polyethylene glycol derivative containing dibenzocyclooctyne. DBCO-PEG-Amine is a universal, modular "bridge molecule": it forms stable covalent linkage with target materials (e.g., MSN or polymers) via the amino group at one end, while the DBCO group at the other end enables efficient, specific, and biocompatible click chemical conjugation with any azide-bearing biological entities (e.g., bacteria, cells) in subsequent steps .

HY-168940E

NH2-PEG600-COOH	Biochemical Assay Reagents	Cancer
NH2-PEG600-COOH consists of an NH2 group, PEG units and a carboxyl group (-COOH). NH2-PEG600-COOH helps improve the biocompatibility of the resulting nanocomplexes in cancer cells. NH2-PEG600-COOH can be used in cancer-related research .

Cat. No.	Product Name	Type

HY-W243303J

Poly(acrylic acid) (MW 250000)	Biochemical Assay Reagents
Poly(acrylic acid) (MW 250000) is a synthetic cationic electrolyte containing abundant carboxyl groups (-COOH), which exhibits excellent water absorption and retention properties and is often cross-linked to form hydrogels. Poly(acrylic acid) (with a molecular weight of 250,000). Poly(acrylic acid) (MW 250000) can be used as a non-collagenous analog in the biomimetic mineralization research of type I collagen. Poly(acrylic acid) (MW 250000) has pH responsiveness and biocompatibility and is often used as a drug carrier, surface modifier and functional material .

Poly(acrylic acid) (MW 250000)

Biochemical Assay Reagents

Poly(acrylic acid) (MW 250000) is a synthetic cationic electrolyte containing abundant carboxyl groups (-COOH), which exhibits excellent water absorption and retention properties and is often cross-linked to form hydrogels. Poly(acrylic acid) (with a molecular weight of 250,000). Poly(acrylic acid) (MW 250000) can be used as a non-collagenous analog in the biomimetic mineralization research of type I collagen. Poly(acrylic acid) (MW 250000) has pH responsiveness and biocompatibility and is often used as a drug carrier, surface modifier and functional material .

HY-174929A

DBCO-PEG5000-Amine DBCO-PEG5000-NH2	Biochemical Assay Reagents
DBCO-PEG5000-Amine (DBCO-PEG5000-NH2) is a polyethylene glycol derivative containing dibenzocyclooctyne. DBCO-PEG-Amine is a universal, modular "bridge molecule": it forms stable covalent linkage with target materials (e.g., MSN or polymers) via the amino group at one end, while the DBCO group at the other end enables efficient, specific, and biocompatible click chemical conjugation with any azide-bearing biological entities (e.g., bacteria, cells) in subsequent steps .

DBCO-PEG5000-Amine

DBCO-PEG5000-NH2

Biochemical Assay Reagents

DBCO-PEG5000-Amine (DBCO-PEG5000-NH2) is a polyethylene glycol derivative containing dibenzocyclooctyne. DBCO-PEG-Amine is a universal, modular "bridge molecule": it forms stable covalent linkage with target materials (e.g., MSN or polymers) via the amino group at one end, while the DBCO group at the other end enables efficient, specific, and biocompatible click chemical conjugation with any azide-bearing biological entities (e.g., bacteria, cells) in subsequent steps .

HY-168940E

NH2-PEG600-COOH	Biochemical Assay Reagents
NH2-PEG600-COOH consists of an NH2 group, PEG units and a carboxyl group (-COOH). NH2-PEG600-COOH helps improve the biocompatibility of the resulting nanocomplexes in cancer cells. NH2-PEG600-COOH can be used in cancer-related research .

Cat. No.	Product Name	Target	Research Area

HY-P5832

BMP2-derived peptide	TGF-beta/Smad RUNX	Metabolic Disease
BMP2-derived peptide is an osteogenic inducer and BMP receptor ligand. BMP2-derived peptide binds to BMP receptors on the cell surface to form a complex, activates the downstream Smad signaling pathway, and regulates the expression of osteogenic transcription factors. BMP2-derived peptide effectively promotes the adhesion, proliferation, osteogenic differentiation and mineralization of bone marrow mesenchymal stem cells, significantly up-regulates the mRNA levels of OCN, Runx2 and type I collagen, and increases alkaline phosphatase activity and calcium deposition. BMP2-derived peptide induces osteoblast differentiation and ectopic bone regeneration, and improves cranial bone defect repair. Meanwhile, BMP2-derived peptide enhances the cytocompatibility of mesoporous silica nanoparticles, synergistically increases osteogenic activity with Dexamethasone (HY-14648), serving as an important tool for bone defect repair research .

Cat. No.	Product Name		Classification

HY-174929A

DBCO-PEG5000-Amine DBCO-PEG5000-NH2		DBCO
DBCO-PEG5000-Amine (DBCO-PEG5000-NH2) is a polyethylene glycol derivative containing dibenzocyclooctyne. DBCO-PEG-Amine is a universal, modular "bridge molecule": it forms stable covalent linkage with target materials (e.g., MSN or polymers) via the amino group at one end, while the DBCO group at the other end enables efficient, specific, and biocompatible click chemical conjugation with any azide-bearing biological entities (e.g., bacteria, cells) in subsequent steps .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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