6 Results for "

muscarinic ganglionic receptor

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "muscarinic ganglionic receptor" in MCE Product Catalog:

  • Targets Recommended:
1
1 Cited Publications
Cat. No.: HY-N0340
CAS No.: 149-64-4
Synonyms: Hyoscine butylbromide; (-)-Scopolamine butylbromide; Butylscopolamine bromide
Scopolamine butylbromide (Hyoscine butylbromide) is an orally active anticholinergic agent and spasmolytic. Scopolamine butylbromide binds with high affinity to rat cardiac M2 (Ki 83 nmol/L), hM2 (Ki 233 nmol/L), rat intestinal M3 (Ki 290 nmol/L) and hM3 (Ki 643 nmol/L) muscarinic receptors. Scopolamine butylbromide exerts a dose-dependent antagonistic effect on Carbachol-induced gastrointestinal smooth muscle spasm. Scopolamine butylbromide can be used for the research of abdominal colic and pain associated with gastrointestinal spasm, functional abdominal pain, chronic gastropathy and gastric ulcer .
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Cat. No.: HY-B0416
CAS No.: 65-29-2
Research Areas:  

Neurological Disease

Gallamine Triethiodide is a blood-brain barrier-permeable skeletal muscle relaxant. Gallamine Triethiodide induces skeletal muscle paralysis by blocking acetylcholine. Gallamine Triethiodide directly stimulates intracardiac β receptors. Gallamine Triethiodide prolongs the duration of afterdischarge in the cat cerebral cortex. Gallamine Triethiodide can be used in studies related to convulsive disorders .
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Cat. No.: HY-120915
CAS No.: 144860-79-7
Target:  

mAChR

Research Areas:  

Neurological Disease

L 689660 maleate, a cholinomimetic agent, is a selective M1 and M3 muscarinic receptors agonist. L 689660 maleate is a potent M1 muscarinic receptor full agonist in the rat superior cervical ganglion (pEC50 of 7.3). L 689660 maleate is a potent M3 receptors agonist in the guinea-pig ileum myenteric plexus-longitudinal muscle or in trachea (pEC50 of 7.5 and 7.7, respectively) .
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Cat. No.: HY-30647
CAS No.: 3576-73-6
Target:  

mAChR

Research Areas:  

Neurological Disease

RS-86 is a potent, central acting, and selective muscarinic acetylcholine receptor agonist. RS-86 exhibits typical cholinergic excitatory effects, such as inducing smooth muscle contraction, ganglion depolarization, central hypothermia, etc. RS-86 can be used for research on Alzheimer's disease .
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Cat. No.: HY-105642
CAS No.: 77-51-0
Research Areas:  

Neurological Disease

Isoaminile is an antitussive agent and an anticholinergic compound with antimuscarinic and antinicotinic properties. Isoaminile blocks the effects of acetylcholine and McN-A-343 at ganglionic sites, inhibits responses to preganglionic sympathetic and splanchnic nerve stimulation, and does not affect postganglionic nerve- or adrenergic-mediated responses. Isoaminile inhibits nictitating membrane contraction and induced hypertension, suppresses isolated guinea pig atrial activity, and stimulates central vagal nerve activity to trigger bradycardia. Isoaminile exerts effects of antitussive action, respiratory inhibition, central nervous system excitation, and cardiovascular function regulation .
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Cat. No.: HY-B1778C
CAS No.: 541-19-5
Synonyms: Suxamethonium iodide
Target:  

nAChR mAChR

Research Areas:  

Neurological Disease

Succinylcholine iodide (Suxamethonium iodide) is a depolarizing neuromuscular blocker with rapid onset and short duration of action. Succinylcholine iodide also acts as an agonist of the Acetylcholine receptor. Succinylcholine iodide is used for emergency airway management .
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