65-29-2
65-29-2
Chemical Structure
Gallamine Triethiodide
- CAS No.: 65-29-2
- Formula:C30H60I3N3O3
- Molecular Weight:891.53
IUPAC Name: 2,2',2''-(benzene-1,2,3-triyltris(oxy))tris(N,N,N-triethylethan-1-aminium) iodide
InChIKey: REEUVFCVXKWOFE-UHFFFAOYSA-K
SMILES: CC[N+](CC)(CC)CCOC(C(OCC[N+](CC)(CC)CC)=CC=C1)=C1OCC[N+](CC)(CC)CC.[I-].[I-].[I-]
Biological Activity: Gallamine Triethiodide is a blood-brain barrier-permeable skeletal muscle relaxant. Gallamine Triethiodide induces skeletal muscle paralysis by blocking acetylcholine. Gallamine Triethiodide directly stimulates intracardiac β receptors. Gallamine Triethiodide prolongs the duration of afterdischarge in the cat cerebral cortex. Gallamine Triethiodide can be used in studies related to convulsive disorders[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Gallamine Triethiodide | 99.56% | Gallamine Triethiodide is a blood-brain barrier-permeable skeletal muscle relaxant. Gallamine Triethiodide induces skeletal muscle paralysis by blocking acetylcholine. Gallamine Triethiodide directly stimulates intracardiac β receptors. Gallamine Triethiodide prolongs the duration of afterdischarge in the cat cerebral cortex. Gallamine Triethiodide can be used in studies related to convulsive disorders. | ||||||||||||||||||||
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Gallamine Triethiodide (Standard) | ≥98% | Gallamine Triethiodide (Standard) is the analytical standard of Gallamine Triethiodide. This product is intended for research and analytical applications. Gallamine Gallamine Triethiodide is a blood-brain barrier-permeable skeletal muscle relaxant. Gallamine Triethiodide induces skeletal muscle paralysis by blocking acetylcholine. Gallamine Triethiodide directly stimulates intracardiac β receptors. Gallamine Triethiodide prolongs the duration of afterdischarge in the cat cerebral cortex. Gallamine Triethiodide can be used in studies related to convulsive disorders. | ||||||||||||||||||||
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Cetamolol hydrochloride | Cetamolol hydrochloride is classified as a potent β1-blocker with intrinsic sympathomimetic activity and cardioselectivity. Low and medium doses of Cetamolol and Atenolol produce a more prolonged inhibitory effect than the same doses of Propranolol and Dexpropranolol. | |||||||||||||||||||||
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MG624 | 97.57% | MG624 is a potent and selective neuronal α7 nAChR antagonist with a Ki of 106 nM. | ||||||||||||||||||||
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2-(2-Methoxyphenoxy)ethylamine hydrochloride (Standard) | 2-(2-Methoxyphenoxy)ethylamine hydrochloride (Standard) is the analytical standard of 2-(2-Methoxyphenoxy)ethylamine (hydrochloride) (HY-107847). This product is intended for research and analytical applications. 2-(2-Methoxyphenoxy)ethylamine hydrochloride (Compound 2b) is a mixed agonist/antagonist. 2-(2-Methoxyphenoxy)ethylamine hydrochloride is a5-HT1A receptor partial agonist and a α1-adrenergic receptor antagonist. 2-(2-Methoxyphenoxy)ethylamine hydrochloride can be used for neurological diseases research, such as anxiety, depression and psychosis. | |||||||||||||||||||||
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Pyrogallol triacetate | Pyrogallol triacetate (NSC 24068) is used as an antiasthmatic. | |||||||||||||||||||||
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Gallamine | Gallamine is an allosteric, selective muscarinic M2 acetylcholine receptor antagonist (EC50: 130 nM for [3H]NMS dissociation from porcine muscarinic M2 receptors). Gallamine is also an acetylcholinesterase inhibitor (IC50s : 1070 μM, 1480 μM, 235 μM for EeAChE, hAChE, hBChE, respectively (in the absence of MeCN)). Gallamine increases free norepinephrine levels. Gallamine can be used as a muscle relaxant. | |||||||||||||||||||||
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Domiphen bromide (Standard) | ≥98% | Domiphen bromide (Standard) is the analytical standard of Domiphen bromide (HY-B1467). This product is intended for research and analytical applications. Domiphen bromide is a cationic active quaternary ammonium salt and also an inhibitor of HERG channels (IC50: 9 nM), aminopeptidase-like enzymes, Escherichia coli alkaline phosphatase, and α-chymotrypsin. Domiphen bromide has multiple activities such as antibacterial, antimalarial, and disinfectant properties, and it is also a synergist of Colistin (HY-113678). Domiphen bromide can be used as a chemical preservative and a cationic surfactant, and it can also be used in the research of bacterial infectious diseases such as pharyngitis, thrush, and oral ulcers. | ||||||||||||||||||||
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Tamsulosin impurity 6 | Tamsulosin impurity 6 is an impurity of Tamsulosin. | |||||||||||||||||||||
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1,2,3-Trimethoxybenzene | 99.55% | 1,2,3-Trimethoxybenzene is an odorant. 1,2,3-Trimethoxybenzene can be isolated from the water extract of ripe Pu-erh tea. 1,2,3-Trimethoxybenzene can distinguish RIPT from RAPT extracts. 1,2,3-Trimethoxybenzene is a chemical intermediate for the synthesis of bioactive compounds, dyes, and polymers. | ||||||||||||||||||||
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Tamsulosin impurity 1 | Tamsulosin impurity 1 is an impurity of Tamsulosin (HY-B0661). | |||||||||||||||||||||
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6,6'-(1,4-Phenylenebis(oxy))bis(hexan-1-ol) | 6,6'-(1,4-Phenylenebis(oxy))bis(hexan-1-ol) is a drug impurity. | |||||||||||||||||||||
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References
- [1]. Enroth-Cugell C, et al. Gallamine triethiodide (flaxedil) and cat retinal ganglion cell responses. J Physiol. 1970;208(3):677-689. [Content Brief]
- [2]. Halpern LM, et al. Flaxedil (gallamine triethiodide): evidence for a central action. Science. 1967;155(3770):1685-1687. [Content Brief]
- [3]. Kennedy BR. Cardiovascular effects of gallamine triethiodide in man. Br J Anaesth. 1968;40(10):773-780.
