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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
nonclassical
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "nonclassical" in MCE Product Catalog:
2
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2
2 Cited Publications
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LSN 3213128 is a selective, nonclassical, orally bioavailable antifolate with potent and specific inhibitory activity for aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT) with IC50 of 16 nM. LSN 3213128 exhibits anti-tumor activity .
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Cat. No.: HY-W004078
CAS No.: 696-60-6
Category:
other families Monophenols Metabolic Disease Phenols Plants Endogenous metabolite Disease Research Fields
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Cat. No.: HY-P990061
CAS No.: 2640981-19-5
Synonyms: JTX 8064
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Cat. No.: HY-P990813
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Cat. No.: HY-146753
CAS No.: 2758387-58-3
HIV-1 inhibitor-20 is a potent HIV-1 inhibitor by non-classical isosteric replacement of amide to 1,2,4-oxadiazoles .
Cat. No.: HY-163399
CAS No.: 54387-80-3
Antibacterial agent 197 (compound 1-deAA) is a termination inhibitor of non-classical anhydroglycosyl receptors and anhydrowall peptide-type peptidoglycan (PG) in bacterial TGase, with activity against Staphylococcus aureus. Antibacterial agent 197 synergizes with Vancomycin (HY-B0671) and is its antibacterial adjuvant .
Cat. No.: HY-W004078R
CAS No.: 696-60-6
Cat. No.: HY-P10669
CAS No.: 2999646-19-2
Cat. No.: HY-114719
CAS No.: 117009-82-2
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A 854777 is a homologous piperazine derivative with anti-inflammatory activity. A 854777 has non-classical immunosuppressive properties. A 854777 can be used to suppress diseases associated with inflammation .
Cat. No.: HY-108282
CAS No.: 18559-59-6
Synonyms: (S)-AQL 208 hydrochloride; (S)-TMQ hydrochloride
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(S)-Trimetoquinol hydrochloride (Compound 1) is a apotent, nonselective, nonclassical β-adrenergic agonist and nonprostanoid thromboxane A2/prostaglandin H2 antagonist. (S)-Trimetoquinol hydrochloride can be used for research of neurological and cardiovascular disease .
Cat. No.: HY-107981R
CAS No.: 1941211-99-9
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LSN 3213128 (Standard) is the analytical standard of LSN 3213128 (HY-107981). This product is intended for research and analytical applications. LSN 3213128 is a selective, nonclassical, orally bioavailable antifolate with potent and specific inhibitory activity for aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT) with IC50 of 16 nM. LSN 3213128 exhibits anti-tumor activity .
Cat. No.: HY-111289
CAS No.: 852838-07-4
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Tec-IN-14 blocks the interaction between Tec kinase and FGF2 with an IC50 of 7.0 μM. Tec-IN-14 inhibits the non-classical secretion of FGF2 in cells. Tec-IN-14 suppresses the tyrosine phosphorylation of FGF2 in a cellular environment. Tec-IN-14 is applicable to research related to cancer .
Cat. No.: HY-182390
Research Areas:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Ferroptosis-IN-24 is a non-classical ferroptosis inhibitor capable of crossing the blood-brain barrier, with nanomolar inhibitory activity against ferroptosis induced by RSL3 (HY-100218A) and Erastin (HY-15763). Ferroptosis-IN-24 alleviates oxidative stress, reduces lipid peroxidation accumulation, and restores redox homeostasis. Ferroptosis-IN-24 is applicable to research related to cerebral ischemia-reperfusion injury and acute liver injury .
Cat. No.: HY-175445
CAS No.: 2417369-99-2
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GNE-5472 is a potent bifunctional ERα PRRTAC degrader, with its E3 ligand being a pan-IAP antagonist. GNE-5472 antagonizes cIAP1/2, activating the non-classical NF-κB pathway, resulting in a significant upregulation of TNFα expression. GNE-5472 inhibits the proliferation of breast cancer cells and induces cell apoptosis. GNE-5472 can be used for the study of breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
