319-78-8

D-Isoleucine Chemical Structure
319-78-8

Chemical Structure

D-Isoleucine

Synonym(s): (R)-Isoleucine

  • CAS No.: 319-78-8
  • Formula:C6H13NO2
  • Molecular Weight:131.18

IUPAC Name: D-isoleucine

InChIKey: AGPKZVBTJJNPAG-RFZPGFLSSA-N

SMILES: CC[C@@H](C)[C@@H](N)C(O)=O

Biological Activity: D-Isoleucine is a selective competitive activator of the Asc-1 antiporter (Ki=0.98 mM). D-Isoleucine promotes the release of D-serine and glycine by binding to the Asc-1 protein on the neuronal cell membrane, and enhances NMDA receptor-dependent synaptic plasticity. D-Isoleucine can be used in the study of neurodegenerative diseases (such as Alzheimer's disease and schizophrenia). D-Isoleucine also acts as a non-classical D-amino acid, interferes with bacterial peptidoglycan synthesis, and inhibits the formation of Staphylococcus aureus biofilm, and has potential antibacterial application value[1][2].

Cat. No. Product Name Purity Description Pricing
HY-I1070
D-Isoleucine 99.83% D-Isoleucine is a selective competitive activator of the Asc-1 antiporter (Ki=0.98 mM). D-Isoleucine promotes the release of D-serine and glycine by binding to the Asc-1 protein on the neuronal cell membrane, and enhances NMDA receptor-dependent synaptic plasticity. D-Isoleucine can be used in the study of neurodegenerative diseases (such as Alzheimer's disease and schizophrenia). D-Isoleucine also acts as a non-classical D-amino acid, interferes with bacterial peptidoglycan synthesis, and inhibits the formation of Staphylococcus aureus biofilm, and has potential antibacterial application value.
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