L-Isoleucine-13C6
Based on 1 Customer Validation
L-Isoleucine-13C6 is the 13C-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid. L-Isoleucine is an essential amino acid.
For research use only. We do not sell to patients.
- Purity: 99.77%
- CAS No.: 201740-82-1
- Formula: 13C6H13NO2
- Molecular Weight:137.13
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 201740-82-1
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Unlabeled Cas 73-32-5
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Appearance Solid
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Molecular Weight 137.13
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Formula 13C6H13NO2
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Color White to off-white
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SMILES
N[13C@H]([13C](O)=O)[13C@H]([13CH2][13CH3])[13CH3]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 12.5 mg/mL (91.15 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Korean - KR (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Arkhipov SG, et al. New hydrophobic L-amino acid salts: maleates of L-leucine, L-isoleucine and L-norvaline. Acta Crystallogr C Struct Chem. 2015 Jul;71(Pt 7):584-92. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 7.2924 mL | 36.4618 mL | 72.9235 mL | 182.3088 mL |
| 5 mM | 1.4585 mL | 7.2924 mL | 14.5847 mL | 36.4618 mL | |
| 10 mM | 0.7292 mL | 3.6462 mL | 7.2924 mL | 18.2309 mL | |
| 15 mM | 0.4862 mL | 2.4308 mL | 4.8616 mL | 12.1539 mL | |
| 20 mM | 0.3646 mL | 1.8231 mL | 3.6462 mL | 9.1154 mL | |
| 25 mM | 0.2917 mL | 1.4585 mL | 2.9169 mL | 7.2924 mL | |
| 30 mM | 0.2431 mL | 1.2154 mL | 2.4308 mL | 6.0770 mL | |
| 40 mM | 0.1823 mL | 0.9115 mL | 1.8231 mL | 4.5577 mL | |
| 50 mM | 0.1458 mL | 0.7292 mL | 1.4585 mL | 3.6462 mL | |
| 60 mM | 0.1215 mL | 0.6077 mL | 1.2154 mL | 3.0385 mL | |
| 80 mM | 0.0912 mL | 0.4558 mL | 0.9115 mL | 2.2789 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
L-Isoleucine-13C6 Related Classifications
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