852838-07-4

Tec-IN-14 Chemical Structure
852838-07-4

Chemical Structure

Tec-IN-14

  • CAS No.: 852838-07-4
  • Formula:C18H16BrN3O4
  • Molecular Weight:418.25

IUPAC Name: (7-bromo-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)methyl 4-acetyl-3,5-dimethyl-1H-pyrrole-2-carboxylate

InChIKey: FSNZIHKIOIUBHQ-UHFFFAOYSA-N

SMILES: O=C(OCC=1N=C2C=CC(Br)=CN2C(=O)C1)C=3NC(=C(C(=O)C)C3C)C

Biological Activity: Tec-IN-14 blocks the interaction between Tec kinase and FGF2 with an IC50 of 7.0 μM. Tec-IN-14 inhibits the non-classical secretion of FGF2 in cells. Tec-IN-14 suppresses the tyrosine phosphorylation of FGF2 in a cellular environment. Tec-IN-14 is applicable to research related to cancer[1].

Cat. No. Product Name Purity Description Pricing
HY-111289
Tec-IN-14 Tec-IN-14 blocks the interaction between Tec kinase and FGF2 with an IC50 of 7.0 μM. Tec-IN-14 inhibits the non-classical secretion of FGF2 in cells. Tec-IN-14 suppresses the tyrosine phosphorylation of FGF2 in a cellular environment. Tec-IN-14 is applicable to research related to cancer.
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This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References