852838-07-4
Chemical Structure
Tec-IN-14
- CAS No.: 852838-07-4
- Formula:C18H16BrN3O4
- Molecular Weight:418.25
IUPAC Name: (7-bromo-4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl)methyl 4-acetyl-3,5-dimethyl-1H-pyrrole-2-carboxylate
InChIKey: FSNZIHKIOIUBHQ-UHFFFAOYSA-N
SMILES: O=C(OCC=1N=C2C=CC(Br)=CN2C(=O)C1)C=3NC(=C(C(=O)C)C3C)C
Biological Activity: Tec-IN-14 blocks the interaction between Tec kinase and FGF2 with an IC50 of 7.0 μM. Tec-IN-14 inhibits the non-classical secretion of FGF2 in cells. Tec-IN-14 suppresses the tyrosine phosphorylation of FGF2 in a cellular environment. Tec-IN-14 is applicable to research related to cancer[1].
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Tec-IN-14 | Tec-IN-14 blocks the interaction between Tec kinase and FGF2 with an IC50 of 7.0 μM. Tec-IN-14 inhibits the non-classical secretion of FGF2 in cells. Tec-IN-14 suppresses the tyrosine phosphorylation of FGF2 in a cellular environment. Tec-IN-14 is applicable to research related to cancer. | |||||||||||||||||||||
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Keywords