538-03-4
Chemical Structure
Oxophenarsine hydrochloride
- CAS No.: 538-03-4
- Formula:C6H7AsClNO2
- Molecular Weight:235.50
IUPAC Name: 2-amino-4-(oxoarsanyl)phenol hydrochloride
InChIKey: JRIGVWDKYXCHMG-UHFFFAOYSA-N
SMILES: O=[As]C1=CC=C(C(N)=C1)O.Cl
Biological Activity: Oxophenarsine hydrochloride is an anti-syphilitic agent, and also has non-classical applications including treating chronic discoid lupus erythematosus, inhibiting HIV-1 protein synthesis, and prolonging the duration of insulin action. Oxophenarsine hydrochloride forms an unstable insulin complex via sulfhydryl groups or free amino groups, thereby prolonging the hypoglycemic effect of insulin. Oxophenarsine hydrochloride inhibits HIV-1-specific protein synthesis and virus production[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Oxophenarsine hydrochloride | Oxophenarsine hydrochloride is an anti-syphilitic agent, and also has non-classical applications including treating chronic discoid lupus erythematosus, inhibiting HIV-1 protein synthesis, and prolonging the duration of insulin action. Oxophenarsine hydrochloride forms an unstable insulin complex via sulfhydryl groups or free amino groups, thereby prolonging the hypoglycemic effect of insulin. Oxophenarsine hydrochloride inhibits HIV-1-specific protein synthesis and virus production. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
[1]. LEONARD CS. Influence of oxophenarsine on hypoglycemic action of insulin. Proc Soc Exp Biol Med. 1948 Jan;67(1):89-92.
[Content Brief] - [2]. Gupta P, et al. Oxophenarsine, an antisyphilis drug inhibits HIV-1-specific protein synthesis in acutely and persistently infected lymphocytes. AIDS research and human retroviruses. 1990 Dec;6(12):1417-23. [Content Brief]
-
[3]. HYMAN AB. Oxophenarsine hydrochloride in treatment of lupus erythematosus. Arch Derm Syphilol. 1946 Jan;53:26-30.
[Content Brief]
Keywords
