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ovulation

" in MedChemExpress (MCE) Product Catalog:

39

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17

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1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N12634
    Pregnant mare serum gonadotropin

    PMSG

    		 Endogenous Metabolite Endocrinology
    Pregnant mare serum gonadotropin (PMSG) is a gonadotropin used to promote follicular development and ovulation in animals. PMSG exerts its regulatory effects by stimulating changes in blood hormones, gonadotropins, and cytoplasmic estradiol receptors in the anterior pituitary and hypothalamus. PMSG is commonly used in livestock to improve reproductive efficiency and can also be utilized for research on estrous cycle regulation .
    Pregnant mare serum gonadotropin
  • HY-105634A
    Nomegestrol acetate

    		Progesterone Receptor Endocrinology Cancer
    Nomegestrol acetate is an orally active, highly selective progestogen and a progesterone receptor complete agonist. Nomegestrol acetate inhibits ovulation. Nomegestrol acetate is also effective in inhibiting the proliferation of human endometrial cancer RL95-2 cells in vitro and in vivo. Nomegestrol acetate can be used in cancer (especially endometrial cancer) and contraceptive studies .
    Nomegestrol acetate
  • HY-W011100
    Cyclofenil

    		Dengue Virus Estrogen Receptor/ERR Flavivirus Infection Endocrinology
    Cyclofenil is a selective estrogen receptor modulator and an ovulation-inducing agent. Cyclofenil shows an inhibitory effect on dengue virus replication in Vero cells with an EC50 of 1.62 μM. Cyclofenil has anti-dengue-virus activity .
    Cyclofenil
  • HY-P0205
    Saralasin

    [Sar1,Ala8] Angiotensin II

    		 Angiotensin Receptor Cardiovascular Disease Inflammation/Immunology
    Saralasin ([Sar1,Ala8] Angiotensin II) is an octapeptide analog of angiotensin II. Saralasin is a competitive angiotensin II receptor antagonist with a Ki value of 0.32 nM for 74% of the binding sites, and has partial agonist activity as well. Saralasin can be used for the research of renovascular hypertension, renin-dependent (angiotensinogenic) hypertension .
    Saralasin
  • HY-P3582
    sGnRH-A

    		GnRH Receptor Endocrinology
    sGnRH-A is a salmon gonadotropin-releasing hormone (GnRH) analogue. sGnRH-A stimulates growth hormone secretion. sGnRH-A also can be used as an inducer of ovulation by artificial insemination .
    sGnRH-A
  • HY-113157
    Estrone 3-glucuronide

    		Drug Metabolite Endogenous Metabolite Endocrinology
    Estrone 3-glucuronide is a dominant urinary metabolite of Estradiol (HY-B0141) and urinary marker for female fertile window prediction. Estrone 3-glucuronide can be used in combination with luteinizing hormone in ovulation prediction kits [2].
    Estrone 3-glucuronide
  • HY-P0205B
    Saralasin TFA

    [Sar1,Ala8] Angiotensin II TFA

    		 Angiotensin Receptor Cardiovascular Disease Inflammation/Immunology
    Saralasin ([Sar1,Ala8] Angiotensin II) TFA is an octapeptide analog of angiotensin II. Saralasin TFA is a competitive angiotensin II receptor antagonist with a Ki value of 0.32 nM for 74% of the binding sites, and has partial agonist activity as well. Saralasin TFA can be used for the research of renovascular hypertension, renin-dependent (angiotensinogenic) hypertension .
    Saralasin TFA
  • HY-19464
    Org 43553

    		GnRH Receptor Estrogen Receptor/ERR Endocrinology
    Org 43553 is an orally active and low molecular weight (LMW) luteinizing hormone receptor (LH-R) agonist. Org 43553 shows agonistic activity to human LH and FSH receptors with EC50 values of 3.7 and 110 nM, respectively. Org 43553 can be used for the research of endocrine .
    Org 43553
  • HY-121314
    Cloprostenol

    		Prostaglandin Receptor Metabolic Disease
    Cloprostenol is a prostaglandin F-2α (PGF2α (HY-12956)) analogue. Cloprostenol induces luteolysis in marmoset monkeys. Cloprostenol can be used for the research of open-cervix pyometra .
    Cloprostenol
  • HY-P4190
    Fsh receptor-binding inhibitor fragment(bi-10)

    		GnRH Receptor Endocrinology
    FSH receptor-binding inhibitor fragment(bi-10) is a potent FSH antagonist. FSH receptor-binding inhibitor fragment(bi-10) blocks the binding of FSH to FSHR, and alteres FSH action at the receptor level. FSH receptor-binding inhibitor fragment(bi-10) results in the suppression of ovulation and causes follicular atresia of mice. FSH receptor-binding inhibitor fragment(bi-10) has the potential for utilizing to restrain the carcinogenesis of ovarian cancer by down-regulating overexpression of FSHR and ERβ in the ovaries .
    Fsh receptor-binding inhibitor fragment(bi-10)
  • HY-118860
    Corifollitropin alfa

    Org 36286; MK-8962

    		 Estrogen Receptor/ERR Endocrinology
    Corifollitropin alfa (Org 36286) is a long-acting recombinant follicle-stimulating hormone (FSH) analog. Corifollitropin alfa is a FSH Receptor agonist with an EC50 of 5.0 pM. Corifollitropin alfa stimulates ovulation and can be used in the research of infertility .
    Corifollitropin alfa
  • HY-B1341
    Norethynodrel

    Enidrel; SC-4642; NSC 15432

    		 Endogenous Metabolite Progesterone Receptor Cancer
    Norethynodrel (Enidrel; SC-4642) is an orally active progestogen analog that reduces estrogen-like effects and enhances progestogen-like responses in endometrial stromal cells. Norethynodrel also promotes cell maturation and predecidual cell formation by inducing organelle hyperplasia and glycogen accumulation. Norethynodrel competitively inhibits drug-metabolizing enzymes in rat liver microsomes, thereby prolonging Pentobarbital sleep time, while exhibiting multiple effects including reduced body weight gain, attenuated heart rate elevation and ovulation inhibition. In mouse models, Norethynodrel significantly increases the incidence of mammary adenocarcinoma, cervical cancer and pituitary tumors. Norethynodrel can be used for mechanism research on related diseases such as mammary adenocarcinoma, cervical cancer, ovarian tubular adenoma and pituitary adenoma .
    Norethynodrel
  • HY-105128
    Epostane

    WIN 32729

    		 3β-HSD Endocrinology
    Epostane (WIN 32729) is an orally active inhibitor for 3β-hydroxysteroid dehydrogenase, with IC50 of 1.45 nM. Epostane blocks ovulation and pregnancy in rats .
    Epostane
  • HY-A0287
    Clomiphene

    Clomifene; (Z/E)-Enclomiphene; (Z/E)-Enclomifene

    		 Estrogen Receptor/ERR Metabolic Disease Cancer
    Clomiphene (Clomifene; (Z/E)-Enclomiphene; (Z/E)-Enclomifene) is an orally active ovulation-inducing agent. Clomiphene binds to hypothalamic estrogen receptors to elevate FSH levels, and exhibits antiestrogenic or estrogenic properties. Clomiphene can induce erturbations during meiotic maturation and cytogenetic abnormalities in mouse oocytes. Clomiphene ameliorates memory impairment in PCOS models. Clomiphene mobilizes cytosolic calcium and reduces viability in prostate cancer cells. Clomiphene can be used for the research of polycystic ovary syndrome (PCOS) and prostate cancer .
    Clomiphene
  • HY-P3582A
    sGnRH-A acetate

    		GnRH Receptor Endocrinology
    sGnRH-A acetate is a salmon gonadotropin-releasing hormone (GnRH) analogue. sGnRH-A acetate stimulates growth hormone secretion. sGnRH-A acetate also can be used as an inducer of ovulation by artificial insemination .
    sGnRH-A acetate
  • HY-A0287S
    Clomiphene-d5 hydrochloride

    Clomifene-d5 hydrochloride; (Z/E)-Enclomiphene-d5 hydrochloride; (Z/E)-Enclomifene-d5 hydrochloride

    		 Isotope-Labeled Compounds Estrogen Receptor/ERR Metabolic Disease Cancer
    Clomifene (Clomifene; (Z/E)-Enclomiphene; (Z/E)-Enclomifene)-d5 hydrochloride is a deuterium labeled Clomifene hydrochloride (HY-A0287A). Clomiphene hydrochloride is an orally active ovulation-inducing agent. Clomiphene hydrochloride binds to hypothalamic estrogen receptors to elevate FSH levels, and exhibits antiestrogenic or estrogenic properties. Clomiphene hydrochloride can induce erturbations during meiotic maturation and cytogenetic abnormalities in mouse oocytes. Clomiphene hydrochloride ameliorates memory impairment in PCOS models. Clomiphene hydrochloride mobilizes cytosolic calcium and reduces viability in prostate cancer cells. Clomiphene hydrochloride can be used for the research of polycystic ovary syndrome (PCOS) and prostate cancer .
    Clomiphene-d5 hydrochloride
  • HY-P4432
    (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon)

    		GnRH Receptor Endocrinology
    (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon) is a GnRH analog that induces ovulation and/or spawning in farmed fish .
    (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon)
  • HY-P3666
    [D-Phe2,6, Pro3]-LH-RH

    		GnRH Receptor Endocrinology
    [D-Phe2,6, Pro3]-LH-RH is a potent luteinizing hormone releasing hormone (LHRH) antagonist .
    [D-Phe2,6, Pro3]-LH-RH
  • HY-P10472
    Azaline B

    		GnRH Receptor Endocrinology
    Azaline B is an antagonist for gonadotropin-releasing hormone (GnRH) with IC50 of 1.37 nM, Azaline B can be used in research of sex hormone-related pathological states, ovulation induction and male contraception .
    Azaline B
  • HY-A0287A
    Clomiphene hydrochloride

    Clomifene hydrochloride; (Z/E)-Enclomiphene hydrochloride; (Z/E)-Enclomifene hydrochloride

    		 Estrogen Receptor/ERR Metabolic Disease Cancer
    Clomiphene (Clomifene; (Z/E)-Enclomiphene; (Z/E)-Enclomifene) hydrochloride is an orally active ovulation-inducing agent. Clomiphene hydrochloride binds to hypothalamic estrogen receptors to elevate FSH levels, and exhibits antiestrogenic or estrogenic properties. Clomiphene hydrochloride can induce erturbations during meiotic maturation and cytogenetic abnormalities in mouse oocytes. Clomiphene hydrochloride ameliorates memory impairment in PCOS models. Clomiphene hydrochloride mobilizes cytosolic calcium and reduces viability in prostate cancer cells. Clomiphene hydrochloride can be used for the research of polycystic ovary syndrome (PCOS) and prostate cancer .
    Clomiphene hydrochloride
  • HY-P3664
    [D-Phe2,D-Ala6]-LH-RH

    Wy 18185

    		 GnRH Receptor Endocrinology
    [D-Phe2,D-Ala6]-LH-RH is a potent LH-RH antagonist. [D-Phe2,D-Ala6]-LH-RH shows anti-LH/FSH-RH and antiovulatory activities .
    [D-Phe2,D-Ala6]-LH-RH
  • HY-P0205A
    Saralasin acetate hydrate

    [Sar1,Ala8] Angiotensin II acetate hydrate

    		 Angiotensin Receptor Cardiovascular Disease Inflammation/Immunology
    Saralasin ([Sar1,Ala8] Angiotensin II) acetate hydrate is an octapeptide analog of angiotensin II. Saralasin acetate hydrate is a competitive angiotensin II receptor antagonist with a Ki value of 0.32 nM for 74% of the binding sites, and has partial agonist activity as well. Saralasin acetate hydrate can be used for the research of renovascular hypertension, renin-dependent (angiotensinogenic) hypertension .
    Saralasin acetate hydrate
  • HY-W040047S
    Pregnanediol 3-glucuronide-13C5

    		Endogenous Metabolite Isotope-Labeled Compounds Endocrinology
    Pregnanediol 3-glucuronide is the main end-metabolite of Progesterone (HY-N0437). Pregnanediol 3-glucuronide is a metabolite of Progesterone formed by hydroxylation and glucuronidation in the liver, with high hydrophilicity and easy excretion through urine. Pregnanediol 3-glucuronide excretion rate of ≥ 9 μmol/24 h can serve as biochemical evidence of ovulation. Pregnanediol 3-glucuronide reflects the quality of the luteal phase, and a level of < 7 μmol/24 h may indicate anovulation or luteal insufficiency. Pregnanediol 3-glucuronide holds significant importance in monitoring female reproductive health, assessing pregnancy, and diagnosing endocrine disorders.
    Pregnanediol 3-glucuronide-13C5
  • HY-P3673
    Lamprey LH-RH I

    		GnRH Receptor Endocrinology
    Lamprey LH-RH I is a gonadotropin-releasing hormone, elevates plasma steroid levels and stimulates ovulation in the lamprey without biological activity in other animal models .
    Lamprey LH-RH I
  • HY-106297
    Tosagestin

    Org 30659

    		 Progesterone Receptor Metabolic Disease Cancer
    Tosagestin(Org 30659) is a 19-nortestosterone–derived progestagen. Tosagestinsuppresses ovarian function to a level sufficient to inhibit ovulation. Tosagestininhibits cell growth in T47D-S cells .
    Tosagestin
  • HY-172299
    Delmadinone acetate

    		Melanocortin Receptor Endocrinology
    Delmadinone acetate is an orally active compound that can control estrus and ovulation in female and male pets. Delmadinone acetate causes adrenal suppression from inhibition of release of ACTH from the pituitary gland .
    Delmadinone acetate
  • HY-123492
    Kentsin

    		Opioid Receptor Neurological Disease Endocrinology
    Kentsin (Thr-Pro-Arg-Lys), a contraceptive tetrapeptide, is originally extracted from hamster embryos. Kentsin prevents the maturation of Graafian follicles and consequently inhibits ovulation, without binding to opioid receptors. Kentsin has opiate properties on gastrointestinal motility .
    Kentsin
  • HY-105634AR
    Nomegestrol acetate (Standard)

    		Reference Standards Progesterone Receptor Endocrinology Cancer
    Nomegestrol acetate (Standard) is the analytical standard of Nomegestrol acetate. This product is intended for research and analytical applications. Nomegestrol acetate is an orally active, highly selective progestogen and a progesterone receptor complete agonist. Nomegestrol acetate inhibits ovulation. Nomegestrol acetate is also effective in inhibiting the proliferation of human endometrial cancer RL95-2 cells in vitro and in vivo. Nomegestrol acetate can be used in cancer (especially endometrial cancer) and contraceptive studies .
    Nomegestrol acetate (Standard)
  • HY-125611
    Fluorogestone acetate

    		GnRH Receptor Endocrinology
    Fluorogestone acetate is a progesterone compound. Fluorogestone acetate inhibits ovulation and synchronizes the estrous cycle in cattle by inhibiting the release of luteinizing hormone (LH) from the pituitary gland .
    Fluorogestone acetate
  • HY-105177
    ORG 33628

    		Progesterone Receptor Endocrinology Cancer
    ORG 33628 is a potent and selective progesterone receptor modulator. ORG 33628 shows anti-progestational and anti-glucocorticoid activity. ORG 33628 shows ovulation-inhibitory activity. ORG 33628 has the potential for the research of breast and endometrium .
    ORG 33628
  • HY-P3671
    [D-Glp1,D-Phe2,D-Trp3,6]-LH-RH

    		GnRH Receptor Endocrinology
    [D-Glp1,D-Phe2,D-Trp3,6]-LH-RH is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Glp1,D-Phe2,D-Trp3,6]-LH-RH acts as a GnRH receptor antagonist .
    [D-Glp1,D-Phe2,D-Trp3,6]-LH-RH
  • HY-P3672
    [D-Ala6]-LH-RH

    		GnRH Receptor Endocrinology
    [D-Ala6]-LH-RH is a Luteinizing-hormone-releasing hormone (LHRH) analogue. [D-Ala6]-LH-RH acts as a GnRH receptor agonist .
    [D-Ala6]-LH-RH
  • HY-W011100R
    Cyclofenil (Standard)

    		Dengue Virus Reference Standards Estrogen Receptor/ERR Flavivirus Infection Endocrinology
    Cyclofenil (Standard) is the analytical standard of Cyclofenil. This product is intended for research and analytical applications. Cyclofenil is a selective estrogen receptor modulator and an ovulation-inducing agent. Cyclofenil shows an inhibitory effect on dengue virus replication in Vero cells with an EC50 of 1.62 μM. Cyclofenil has anti-dengue-virus activity .
    Cyclofenil (Standard)
  • HY-P3317
    Azaline

    Azaline A

    		 GnRH Receptor Endocrinology
    Azaline (Azaline A) is a gonadotropin-releasing hormone (GnRH) receptor antagonist with a KD value of 0.48 nM. Azaline can effectively induce histamine release, with an effect comparable to that of GnRH, and it can completely inhibit ovulation at a dose of 2.0-3.0 μg per female rat. Azaline has potential applications in regulating reproductive functions .
    Azaline
  • HY-149105
    FSH receptor antagonist 1

    		Estrogen Receptor/ERR Endocrinology
    FSH receptor antagonist 1 (compound 10) is a potent antagonist of the G(s)-protein-coupled human follicle-stimulating hormone (FSH) receptor. FSH receptor antagonist 1 exhibits an IC50 of 28 nM on a cell line expressing the human FSH receptor. FSH receptor antagonist 1 significantly inhibits follicle growth and ovulation in an ex vivo mouse model .
    FSH receptor antagonist 1
  • HY-P0037
    Org-30850

    Org 30850ANT

    		 GnRH Receptor Endocrinology
    Org-30850 is a potent LHRH antagonist designed for treating hormone-dependent disorders. In animal studies, a single subcutaneous dose effectively inhibited ovulation in rats and significantly reduced testosterone levels in male rats for up to 48 hours post-administration. Daily doses of Org-30850 in female rats suppressed estrous cycles, decreased uterine and ovarian weights, and lowered estradiol and FSH serum levels. In male rats, prolonged treatment resulted in reversible reductions in gonadal function and testosterone levels, with almost complete recovery observed after cessation of treatment. Unlike comparable LHRH antagonists, Org-30850 exhibited minimal injection site irritation and no edematous reactions, suggesting a more favorable therapeutic profile .
    Org-30850
  • HY-114786
    SC-44463

    		MMP Endocrinology Cancer
    SC-44463 is a synthetic collagenase inhibitor. SC-44463 can inhibit tumor cells invasion. SC-44463 can block ovulation, inhibit action of ovarian interstitial collagenase, and inhibit action of the small metalloproteinase of the rat uterus. SC-44463 can be used for the researches of cancer and endocrinology .
    SC-44463
  • HY-108979
    Medrogestone

    		Progesterone Receptor Endocrinology
    Medrogestone is an orally active Progestin. Medrogestone shows a marked local progestational effect. Medrogestone maintains pregnancy in ovariectomized rats. Medrogestone inhibits ovulation. Medrogestone prevents pregnancy. Medrogestone produces a significant reduction in the severity of benign prostatic hypertrophy .
    Medrogestone
  • HY-182705
    Org 214444-0

    		Estrogen Receptor/ERR Endocrinology
    Org 214444-0 is an orally active, nanomolar-potent and selective FSHR agonist, with EC50 values of 2.0 nM and 1.2 nM in human and rat (measured in CHO cells). Org 214444-0 activates human granulosa cells in vitro, supports rat follicular development and induces ovulation in vivo. Org 214444-0 can be used for the research of infertility .
    Org 214444-0

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