2624-43-3
2624-43-3
Chemical Structure
Cyclofenil
- CAS No.: 2624-43-3
- Formula:C23H24O4
- Molecular Weight:364.44
IUPAC Name: (cyclohexylidenemethylene)bis(4,1-phenylene) diacetate
InChIKey: GVOUFPWUYJWQSK-UHFFFAOYSA-N
SMILES: CC(OC1=CC=C(/C(C2=CC=C(OC(C)=O)C=C2)=C3CCCCC\3)C=C1)=O
Biological Activity: Cyclofenil is a selective estrogen receptor modulator and an ovulation-inducing agent. Cyclofenil shows an inhibitory effect on dengue virus replication in Vero cells with an EC50 of 1.62 μM. Cyclofenil has anti-dengue-virus activity[1][2].
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Cyclofenil | 95.0% | Cyclofenil is a selective estrogen receptor modulator and an ovulation-inducing agent. Cyclofenil shows an inhibitory effect on dengue virus replication in Vero cells with an EC50 of 1.62 μM. Cyclofenil has anti-dengue-virus activity. | ||||||||||||||||||||
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Cyclofenil (Standard) | ≥98% | Cyclofenil (Standard) is the analytical standard of Cyclofenil. This product is intended for research and analytical applications. Cyclofenil is a selective estrogen receptor modulator and an ovulation-inducing agent. Cyclofenil shows an inhibitory effect on dengue virus replication in Vero cells with an EC50 of 1.62 μM. Cyclofenil has anti-dengue-virus activity. | ||||||||||||||||||||
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References
- [1]. Tohma D, et al. An estrogen antagonist, cyclofenil, has anti-dengue-virus activity. Arch Virol. 2019 Jan;164(1):225-234. [Content Brief]
- [2]. Arrieta-Cruz I, et al. Estrogen Receptors Alpha and Beta in POA-AHA Region Regulate Asymmetrically Ovulation. Cell Mol Neurobiol. 2019 Nov;39(8):1139-1149. [Content Brief]
