Search Result
Results for "
peak
" in MedChemExpress (MCE) Product Catalog:
6
Biochemical Assay Reagents
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-13594
-
|
Ce6
|
MOFs
Bcl-2 Family
Caspase
PARP
Apoptosis
Fluorescent Dye
|
Infection
Cancer
|
|
Chlorin e6 is a photosensitizer and has strong absorption peaks at wavelength of 402 and 662 nm, as well as exhibiting intense fluorescence at 668 nm. Chlorin e6 has antimicrobial efficacy and anticancer activity. Chlorin e6 induces cell apoptosis via caspase-3 activation and can be used for the research of cancer .
|
-
-
- HY-137805
-
|
|
Fluorescent Dye
|
Others
|
|
Ferrozine is a spectrophotometric reagent for iron ions, can react with divalent Fe to form a stable magenta complex species. The complex has an absorption peak at 562 nm . Ferrozine-based colorimetric assays can quantify iron in cells
|
-
-
- HY-N6691
-
|
3-Veratroylveracevine
|
Sodium Channel
|
Neurological Disease
|
|
Veratridine (3-Veratroylveracevine) is a plant neurotoxin, a voltage-gated sodium channels (VGSCs) agonist. Veratridine inhibits the peak current of Nav1.7, with an IC50 of 18.39 µM. Veratridine regulates sodium ion channels mainly by activating sodium ion channels, preventing channel inactivation and increasing sodium ion flow .
|
-
-
- HY-111653
-
CycLuc1
2 Publications Verification
|
Reactive Oxygen Species (ROS)
|
Others
|
|
CycLuc1 is a blood-brain barrier permeable luciferase substrate that displays near-infrared (NIR) emission with a peak luminescence wavelength of 599 nm. CycLuc1 can be used for in vivo bioluminescence imaging .
|
-
-
- HY-108309
-
|
Methylenediphosphonic acid
|
Biochemical Assay Reagents
|
Others
|
|
Medronic acid (Methylenediphosphonic acid) is a methylene-substituted bisphosphonate. Medronic acid has an affinity for the surface of hydroxyapatite crystals in the bone matrix and adheres to them. Medronic acid can be used in complex with radioisotopes in bone imaging. Due to its strong metal chelating ability, medronic acid is also used as a water treatment chemical. In addition, medronic acid is used as a solvent additive to improve peak shape and signal of metal-sensitive metabolites in LC/MS analysis .
|
-
-
- HY-D1373
-
HBC
3 Publications Verification
HBC 530
|
Fluorescent Dye
|
Others
|
|
HBC (HBC 530) is a GFP fluorophore-like synthetic dye, with a structurally rigid electron acceptor and a strong electron donor. HBC has a low fluorescence background, and when combined with Pepper (RNA aptamer), HBC forms a tight complex and activates and emits bright fluorescence (Kd of ~3.5 nM). HBC emission peaks vary in different complexes and covers the spectrum from cyan to red. HBC can be used in the live cell imaging of RNA (Em/Ex = 530/485 nm) .
|
-
-
- HY-173117
-
|
|
CaMK
|
Cardiovascular Disease
Cancer
|
|
RA306 is an orally active CaMKIIδ/γ inhibitor with IC50 values of 15, 25, 61, and 420 nM against CaMKIIδ, γ, α, and β isoforms, respectively. RA306 reduces the serine/threonine phosphorylation level of PEAK1, inhibits PEAK1-mediated cancer cell migration and invasion, and attenuates the growth and metastasis of cancer xenografts. RA306 can be used in research related to triple-negative breast cancer and dilated cardiomyopathy .
|
-
-
- HY-118292
-
|
1,4-Diacetoxybenzene
|
Drug Intermediate
|
Others
|
|
Hydroquinone diacetate (1,4-Diacetoxybenzene) is a diester product and also a commonly used synthetic intermediate for agrochemicals and fine chemicals. Hydroquinone diacetate can be produced via the acetylation of hydroquinone (HY-B0951) with acetic anhydride .
|
-
-
- HY-W088089
-
|
|
Fluorescent Dye
|
Cancer
|
|
ICG-carboxylic acid is near-infrared (NIR) fluorescent probe. ICG is a fluorescent dye used in medical diagnostics. ICG has absorption peaking at 800 nm and can absorb the near IR laser energy and release heat in the dyed tissue (Ex/Em = 785/810 nm) .
|
-
-
- HY-131924
-
|
Thio-NAD
|
Biochemical Assay Reagents
|
Others
|
|
Thionicotinamide adenine dinucleotide (Thio-NAD) is a thione-modified analog of the coenzyme nicotinamide adenine dinucleotide (NAD +). Thionicotinamide adenine dinucleotide can replace NAD + in enzymatic reactions and shift the absorption peak to 405 nM, enabling sensitive, real-time kinetic detection of enzyme activity, which is particularly suitable for high-sensitivity diagnostic cyclic detection systems .
|
-
-
- HY-D1445
-
|
|
Fluorescent Dye
|
Metabolic Disease
|
|
PDMPO, a lysosome pH indicator, is an excellent fluorescent acidotropic reagent for fluorescence imaging. PDMPO is a potent tool with which to study acidic organelles of live cells. PDMPO exhibits pH-dependent dual-excitation and dual-emission spectral peaks. PDMPO produces a blue fluorescence in weakly acidic organelles and shifts to yellow in more acidic lysosomes. (Abs=329 nm; Em=440/540 nm) .
|
-
-
- HY-108588
-
NS5806
1 Publications Verification
|
Potassium Channel
|
Cardiovascular Disease
|
|
NS5806, a potent potassium current activator, increases KV4.3/KChIP2 peak current amplitudes with an EC50 of 5.3 μM. NS5806 slows KV4.3 and KV4.2 current dacay in channel complexes containing KChIP2 .
|
-
-
- HY-137296
-
|
|
Fluorescent Dye
|
Others
|
|
Lumogallion is a highly sensitive fluorescent reagent for the detection of aluminum, gallium and other metals. Lumogallion has an excitation wavelength of 490 nm and an emission spectrum in the range of 520 nm to 650 nm, with a peak near 580 nm .
|
-
-
- HY-D0950A
-
|
|
DNA Stain
|
Others
|
|
Methyl Green zinc chloride is a potent fluorescent dye. Methyl Green zinc chloride is a DNA stains of cells and electrophoretic gels. Methyl Green zinc chloride can be used as direct measuring of viability by both microscopy and flow cytometry, with peaks at 633 and 677 nm .
|
-
-
- HY-153081
-
|
|
Fluorescent Dye
|
Others
|
|
The eGFP circRNA will express green fluorescent protein, originally isolated from the jellyfish, Aequorea victoria. The eGFP is a commonly used direct detection reporter in mammalian cell culture, yielding bright green fluorescence with an emission peak at 509 nm. The eGFP circRNA is therefore ideal for monitoring and optimizing transfection efficiency and is recommended as a positive control for circular RNA transfections.
|
-
-
- HY-W440915
-
|
|
Liposome
|
Inflammation/Immunology
|
|
DSPE-PEG2000-FITC is a PEG lipid conjugated with fluorescein. FITC is a green dye with a peak absorption at 494 nm and a maximum emission at 520 nm, which is used for staining biological samples or nanoparticles. DSPE-PEG2000-FITC spontaneously forms lipid bilayers or micelles in water and can be used to prepare liposomes for delivering substances such as mRNA vaccines .
|
-
-
- HY-D1950
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 633 is a fluorescent dye with an absorption peak at approximately 630 nm and a fluorescence emission peak at 651 nm. ATTO 633 can be used in nanomechanical photothermal microscopy studies .
|
-
-
- HY-D2395
-
|
B-PE
|
Fluorescent Dye
|
Others
|
|
B-Phycoerythrin (B-PE) is a light-harvesting pigment protein that can be isolated from the red alga Porphyridium cruentum. The absorption spectrum of B-Phycoerythrin peaks at 545 nm and 563 nm, with a shoulder at 498 nm .
|
-
-
- HY-129527
-
|
|
iGluR
|
Neurological Disease
|
|
GNE-9278 is a highly selective positive allosteric modulator of NMDAR that acts at the GluN1 transmembrane domain (TMD). GNE-9278 acts on activated NMDARs to increase peak current and agonist affinity .
|
-
-
- HY-W440908
-
|
|
Liposome
|
Others
|
|
DSPE-PEG2000-Cy3 is a PEG lipid conjugated with a fluorophore. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy and flow cytometry. The absorption wavelength of the Cy3 fluorophore peaks at 548-552 nm, while its emission wavelength reaches a maximum at 562-570 nm .
|
-
-
- HY-D2083
-
|
|
Fluorescent Dye
|
Metabolic Disease
|
|
BODIPY 540 (purity>98%) is a BODIPY dye.BODIPY dye is a small molecule dye with strong UV absorption ability.Its fluorescence peak is relatively sharp, its quantum yield is high, and it is relatively insensitive to the polarity and pH value of the environment.BODIPY 540 (purity>98%) has a purity higher than 98% and is suitable for cell experiments (Ex/Em = 540/580 nm) .
|
-
-
- HY-W440939
-
|
|
Liposome
|
Others
|
|
Stearic acid-PEG3400-FITC is a PEG lipid which forms micelles in water and can be used for drug delivery applications. The FITC fluorescent can be easily traced by miscroscopy. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
|
-
-
- HY-D2476
-
|
|
Fluorescent Dye
|
Others
|
|
H2S Fluorescent probe 1 (Compound 2) is a fluorescent probe that detects hydrogen sulfide (H2S) with almost no cytotoxicity. Upon the addition of increasing amounts of HS - to DMSO solution of H2S Fluorescent probe 1, a new absorption peak appears gradually at 485 nm. H2S Fluorescent probe 1, the fluorescence intensity notes at 434 nm increasing rapidly by titration of HS - .
|
-
-
- HY-D1499
-
|
|
Fluorescent Dye
|
Others
|
|
Fluorescent red 610 is a fluorescent dye with an excitation peak at 590 nm and an emission peak at 610 nm .
|
-
-
- HY-D2760
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 488 acid is a powerful labeling dye. It will react with the amine group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications.
|
-
-
- HY-D1489
-
|
|
Fluorescent Dye
|
Others
|
|
Ethyl eosin is a fluorescent dye with an absorption peak at 527 nm and an absorption shoulder at 487 nm .
|
-
-
- HY-W781921
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 488 Alkyne is a popular labeling dye used in Click Chemistry reactions. It will react with the azide group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications. BP Fluor 488 is a pure 5-sulfonated rhodamine molecule and it eliminates the lot-to-lot variation caused by two isomers ratio differences.
|
-
-
- HY-D2195
-
|
|
Fluorescent Dye
|
Others
|
|
AgAuSe-PEG-NH2 (1000 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1000 nm that can be used in bioimaging.
|
-
-
- HY-D2198
-
|
|
Fluorescent Dye
|
Others
|
|
AgAuSe-PEG-NH2 (1120 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1120 nm that can be used in bioimaging .
|
-
-
- HY-W133997
-
|
|
Fluorescent Dye
|
Others
|
|
Chromotrope 2R can be used as a chromogenic analytical probe for the quantification of proteins. Basic proteins stained red and the peak wavelength red shifts from 501.6 nm to 567 nm .
|
-
-
- HY-W151629A
-
|
|
Fluorescent Dye
|
Others
|
|
Ferrozine sodium hydrate is a spectrophotometric reagent for iron, can react with divalent Fe to form a stable magenta complex species. The complex has an absorption peak at 562 nm .Ferrozine sodium hydrate-based colorimetric assays can quantify iron in cells
|
-
-
- HY-D1343
-
|
|
Fluorescent Dye
|
|
|
DMNPE-caged D-luciferin is a heterocyclic luminescent compound that is a natural ligand for luciferase, an enzyme used to detect cell activity. Its reaction requires ATP and emits yellow-green light with a peak wavelength of about 530 nm. The luciferin in the DMNPE cage easily crosses the cell membrane.
|
-
-
- HY-151247
-
|
|
GnRH Receptor
|
Cancer
|
|
GnRH-R antagonist 1 (compound 21a) is an orally safe and membrane-permeable GnRH-R antagonist with high binding affinity (IC50=0.57 nM) and potent in vitro antagonistic activity (IC50=2.18 nM). GnRH-R antagonist 1 can be used in studies of advanced prostate cancer and premature LH peaks preventing .
|
-
-
- HY-W039519
-
|
|
Fluorescent Dye
|
Cancer
|
|
7-Methoxycoumarin-3-carboxylic acid is a fluorescent dye with an excitation peak at 355 nm and an emission peak at 405 nm. 7-Methoxycoumarin-3-carboxylic acid can be used to label peptide .
|
-
-
- HY-172269
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 488 is a bright, green-fluorescent dye widely used for labeling aldehydes or ketones in polysaccharides or glycoproteins. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications.
|
-
-
- HY-D2338
-
|
|
Fluorescent Dye
|
Others
|
|
PMBD is a lysosome (Lyso)-targeting fluorescent probe. PMBD selectively and sensitively detects endogenous N-acylethanolamine amidase (NAAA), allowing real-time visual monitoring of endogenous NAAA in living cells. PMBD has a maximum absorption peak at 350 nm. After the metabolism of NAAA, the maximum absorption peak of the product AMBD shifts red to 450 nm, and a significant fluorescence emission signal appears at 550 nm .
|
-
-
- HY-W800680
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 488 DBCO is a popular labeling dye used in copper-free Click Chemistry reactions. It will react with the azide group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications. BP Fluor 488 is a pure 5-sulfonated rhodamine molecule and it eliminates the lot-to-lot variation caused by two isomers ratio differences.
|
-
-
- HY-174486
-
|
|
mRNA
|
Others
|
|
mCherry mRNA (5moU) encodes the fluorescent protein, mCherry, which is derived from DsRed, a protein found in Discosoma sp. mCherry is a monomeric fluorophore with a peak absorption at 587 nm and emission at 610 nm. It is stable and resistant to photobleaching.
|
-
-
- HY-W419643
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Drometrizole trisiloxane is a photostable, oil-soluble chemical UVB and UVA filter with two absorption peaks, one at 303 nm (UVB) and the other at 344 nm (UVA). Drometrizole trisiloxane can be used in cosmetics to absorb ultraviolet radiation .
|
-
-
- HY-W110781
-
|
|
DNA Stain
|
Others
|
|
Basic Blue 20 is a very convenient red-emitting DNA stains. Basic Blue 20 has relatively narrow excitation and emission spectra, with peaks at 633 and 677 nm, respectively. Basic Blue 20 also has a very high resistance to photobleaching .
|
-
-
- HY-W587874
-
|
|
Fluorescent Dye
|
Others
|
|
Disperse Orange 3 is a monoazo dye characterized by a dye content of 90% along with dispersing agents and surfactants; it features two aromatic rings, one of which possesses an amino group while the other is modified with a nitro group, exhibiting a prominent absorption peak at 415 nm.
|
-
-
- HY-156536
-
-
-
- HY-D1905
-
|
|
Fluorescent Dye
|
Cancer
|
|
ICG acid is a fluorescent dye used in medical diagnostics. ICG acid has absorption peaking at 800 nm and can absorb the near IR laser energy and release heat in the dyed tissue. ICG acid has been used in fluorescence-guided surgery to identify critical structures, including intra-abdominal tumors .
|
-
-
- HY-19020
-
|
|
Leukotriene Receptor
|
Cardiovascular Disease
|
|
FK-664 is a leukotriene inhibitor. FK-664 enhances ventricular contractility and shortens the time to peak tension in cardiac cells. FK-664 reduces mean circulating pressure (MCP) in a canine model of heart failure. FK-664 can be used in research on cardiovascular diseases such as heart failure .
|
-
-
- HY-N8472
-
|
|
GABA Receptor
|
Infection
|
|
Chrodrimanin B, a metabolite of a fungal, is a potent, non-open-channel-blocking antagonist on?B.?mori GABAR RDL with an IC50?of 1.13 nM. Chrodrimanin B attenuates the peak current amplitude of the GABA response of RDL with an IC50?of 1.66 nM.?Chrodrimanin B, a meroterpenoid, shows insecticidal activity .
|
-
-
- HY-N6691R
-
|
3-Veratroylveracevine (Standard)
|
Reference Standards
Sodium Channel
|
Neurological Disease
|
|
Veratridine (Standard) is the analytical standard of Veratridine. This product is intended for research and analytical applications. Veratridine (3-Veratroylveracevine) is a plant neurotoxin, a voltage-gated sodium channels (VGSCs) agonist. Veratridine inhibits the peak current of Nav1.7, with an IC50 of 18.39?μM. Veratridine regulates sodium ion channels mainly by activating sodium ion channels, preventing channel inactivation and increasing sodium ion flow .
|
-
-
- HY-N6720
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
T-2 Triol is a trichothecene mycotoxin derived by the metabolism of T-2 toxin. It is less toxic than T-2 toxin . T-2 Triol major metabolites are evaluated in broiler chickens with Half-lives (t1/2λz), Peak plasma concentrations (Cmax) and Tmax values of 9.6 mins, 563 ng/ml , 2.5 mins, respectively .
|
-
-
- HY-W034043
-
|
|
Fluorescent Dye
|
Others
|
|
[Ir (dF (Me) ppy)2 (dtbbpy)]PF6 (Compound 3a) is a blue-green luminescent material. [Ir (dF (Me) ppy)2 (dtbbpy)]PF6 exhibits unstructured emission, with its emission peak maxima located at 498, 512 and 519 nM, respectively. [Ir (dF (Me) ppy)2 (dtbbpy)]PF6 can serve as an electrochemiluminescence-based biological probe .
|
-
![[Ir(dF(Me)ppy)2(dtbbpy)]PF6](//file.medchemexpress.com/product_pic/hy-w034043.gif)
-
- HY-107129
-
|
|
GCGR
|
Metabolic Disease
|
|
MK-3577 is an orally effective glucagon receptor (GCGR) antagonist that reduces hepatic glucose production and lowers blood glucose levels by blocking glucagon receptors on target organs, primarily the liver. Pharmacokinetic analysis in domestic cats indicates that MK-3577 reaches peak levels 3 to 4 hours after oral administration, with a half-life of approximately 15 hours. MK-3577 can be used in diabetes research .
|
-
-
- HY-RS10311
-
|
|
Small Interfering RNA (siRNA)
|
Others
|
|
PEAK3 Human Pre-designed siRNA Set A contains three designed siRNAs for PEAK3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
|
-
PEAK3 Human Pre-designed siRNA Set A
PEAK3 Human Pre-designed siRNA Set A
- HY-RS10310
-
|
|
Small Interfering RNA (siRNA)
|
Others
|
|
PEAK1 Human Pre-designed siRNA Set A contains three designed siRNAs for PEAK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
|
-
PEAK1 Human Pre-designed siRNA Set A
PEAK1 Human Pre-designed siRNA Set A
- HY-D2760A
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 488 acid triTEA is a powerful labeling dye. It will react with the amine group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications.
|
-
- HY-113611
-
|
|
Fungal
|
Infection
|
|
SDZ89-485 is an orally active triazole antifungal agent. The peak concentration of SDZ89-485 is lower, but it exhibits a stronger anti-sporofungus effect in the mouse model than Fluconazole (HY-B0101) with a higher peak concentration. SDZ89-485 can be used in studies on anti-sporofungus .
|
-
- HY-103526
-
|
|
GABA Receptor
|
Neurological Disease
|
|
DPNI-GABA is a nitroindoline cage compound that inhibits GABA(A) receptors and reduces GABA-evoked peak responses with an IC50 value of 0.5 mM .
|
-
- HY-123214
-
|
|
Antibiotic
Bacterial
|
Others
|
|
Rifametane is a new 3-azamethyl-rifamycin with a pharmacokinetic profile superior to that of rifampin and activity with peak serum concentrations higher than that of rifampin in healthy volunteers.
|
-
- HY-D1417
-
|
|
Fluorescent Dye
|
Others
|
|
P-BP-SFAC is a fluorescence molecule. P-BP-SFAC exhibits an apparent absorption band with a peak at about 377 nm, indicative of a stronger ICT effect .
|
-
- HY-116790B
-
|
(Rac)-Penbutolol; (±)-Isopenbutolol
|
Adrenergic Receptor
|
Cardiovascular Disease
|
|
(±)-Penbutolol ((Rac)-Penbutolol) is the racemic mixture of Penbutolol. (±)-Penbutolol is an orally active β-adrenergic receptor antagonist. (±)-Penbutolol antagonizes exercise-induced tachycardia, reduces the increase in peak expiratory flow rate (PEFR) caused by exercise, and decreases resting plasma renin activity (PRA). (±)-Penbutolol reaches peak plasma concentration 1 hour after oral administration, with a half-life of 4.5 hours, and is converted into an active metabolite in the body. (±)-Penbutolol can be used in cardiovascular-related disease research .
|
-
- HY-158556
-
|
|
Drug Derivative
|
Neurological Disease
|
|
2,3-Dimethylethcathinone (2,3-Dmec) hydrochloride is a drug derivative. Ethcathinone increases the peak dopamine efflux after electrical stimulation and slows dopamine reuptake in rats .
|
-
- HY-D0121B
-
|
|
Fluorescent Dye
|
Others
|
|
INDO 1 pentasodium is a cell-impermeant ratiometric, free calcium ion (Ca 2+) fluorescent indicator that can quantitatively monitor dynamic changes in intracellular free Ca 2+ concentrations. When unbound to Ca 2+ (free state), INDO 1 pentasodium exhibits a peak emission wavelength of 485 nm under UV excitation (350 nm). Upon binding to Ca 2+ (bound state), the emission peak shifts to 405 nm. INDO 1 pentasodium is highly photolabile and susceptible to photobleaching, and its emission spectrum may overlap with the autofluorescence of NADH .
|
-
- HY-130916
-
|
5(6)-CarboxyrhodaMine 6G, succinimidyl ester
|
Biochemical Assay Reagents
|
Others
|
|
5(6)-CR6G,SE (5(6)-CarboxyrhodaMine 6G) is a trace fluorescent labeling reagent for fluorescence imaging of protein crystallization. 5(6)-CR6G,SE can efficiently bind to proteins to produce characteristic fluorescence under specific excitation conditions. 5(6)-CR6G,SE shows a peak absorption wavelength of approximately 525 nm and exhibits a peak fluorescence emission wavelength of around 550 nm when excited by a 530 nm green LED .
|
-
- HY-D1419
-
|
|
Fluorescent Dye
|
Others
|
|
mCP-BP-SFAC is a luminogenic molecule. mCP-BP-SFAC exhibits strong sky-blue delayed fluorescence in neat films, with photoluminescence (PL) peaks at ~483 nm and delayed fluorescence lifetimes of 5.4 to 5.7 μs .
|
-
- HY-D1420
-
|
|
Fluorescent Dye
|
Others
|
|
TCP-BP-SFAC is a luminogenic molecule. TCP-BP-SFAC exhibits strong sky-blue delayed fluorescence in neat films, with photoluminescence (PL) peaks at ~483 nm and delayed fluorescence lifetimes of 5.4 to 5.7 μs .
|
-
- HY-B1558
-
|
MCI-2016 free base
|
Calcium Channel
|
Neurological Disease
|
|
Bifemelane is a nootropic compound. Bifemelan causes the first peak by stimulating release from intracellular Ca 2+ stores and the second by capacitive entry through store–operated Ca 2+ channels. Bifemelane will be provided as a pharmacological tool for basic studies on astrocytes .
|
-
- HY-163386
-
|
|
Biochemical Assay Reagents
|
Others
|
|
HFTC-HClO 1 is a stable and sensitive ratiometric probe, which images the endogenous HClO. HFTC-HClO 1 exhibits a main emission peak at 579 nm. HFTC-HClO-1 visualizes HClO generated in the rheumatoid arthritis mouse model .
|
-
- HY-117603
-
|
|
Glucokinase
|
Infection
|
|
CM-10-18 is a potent and orally active inhibitor of both α-glucosidases I and II in vitro and in animals. CM-10-18 inhibits DENV infection of cultured human cells and reduces the peak viremia of DENV in mice .
|
-
- HY-N14038
-
|
|
Fungal
|
Infection
|
|
Crocacin A has anti-yeast and filamentous fungal activity. Crocacin A can inhibit mouse fibroblasts L929. In the microsomes of the calf's heart, Crocacin A can interrupt the bc1 segment of electronic transmission, causes redshift of 569 nm peak in cytochrome B reduction spectrum .
|
-
- HY-170902
-
|
|
GABA Receptor
|
Neurological Disease
|
|
GABAA receptor modulator-4 (Compound 4) is the negative allosteric modulator for GABAA receptor. GABAA receptor modulator-4 inhibits α1β3γ2 GABAA receptor-mediated peak and steady currents with IC50 of 10 μM and 10 μM .
|
-
- HY-N14040
-
|
|
Fungal
|
Infection
|
|
Crocacin B has anti-yeast and filamentous fungal activity. Crocacin B can inhibit mouse fibroblasts L929. In the microsomes of the calf's heart, Crocacin B can interrupt the bc1 segment of electronic transmission, causes redshift of 569 nm peak in cytochrome B reduction spectrum .
|
-
- HY-170903
-
|
|
GABA Receptor
|
Neurological Disease
|
|
GABAA receptor modulator-3 (compound 3b) is a positive allosteric modulator (PAM). GABAA receptor modulator-3 inhibits α1β3γ2 GABAAR at peak and steady state currents with IC50s of 671 and 64 μM, respectively .
|
-
- HY-122792
-
|
|
Endogenous Metabolite
|
Cardiovascular Disease
|
|
Phenyramidol hydrochloride is an anticoagulant and analgesic with activity that increases detection sensitivity in biological samples. Phenyramidol hydrochloride can be oxidized in aqueous media by electrochemical methods to achieve its quantitative analysis. The detection of Phenyramidol hydrochloride using an amino-functionalized multi-walled carbon nanotube-modified glassy carbon electrode showed significant enhancement of the current peak .
|
-
- HY-117715
-
|
|
Phosphodiesterase (PDE)
|
Cardiovascular Disease
|
|
CK-3197 is a weak inhibitor of Peak lll cyclic 3'5'-adenosine monophosphate phosphodiesterase
(CAMP PDEl). CK-3197 has hemodynamic and myocardial energetic effects in vivo. CK-3197 is an imidazolone derivative used as a selective positive inotropic agent for congestive heart failure .
|
-
- HY-171187
-
|
CL 13580
|
Carbonic Anhydrase
|
Cancer
|
|
Chlorzolamide (CL 13580) is a carbonic anhydrase (CA) inhibitor. Chlorzolamide has an effect on the skeletal muscle of rats, which can reduce the tetanic contraction force of soleus and extensor digitorum longus and prolong the relaxation time and peak time of muscle contraction. In addition, Chlorzolamide inhibits tumor cell proliferation and has antitumor activity .
|
-
- HY-W419643R
-
|
|
Biochemical Assay Reagents
Reference Standards
|
Others
|
|
Drometrizole trisiloxane (Standard) is the analytical standard of Drometrizole trisiloxane. This product is intended for research and analytical applications. Drometrizole trisiloxane is a photostable, oil-soluble chemical UVB and UVA filter with two absorption peaks, one at 303 nm (UVB) and the other at 344 nm (UVA). Drometrizole trisiloxane can be used in cosmetics to absorb ultraviolet radiation .
|
-
- HY-W440938
-
|
|
Liposome
|
Others
|
|
Stearic acid-PEG2000-FITC is an amphiphatic polyPEG which can self assemble to form micelles in water. The polymer can be used to encapsulate therapeutic agent. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
|
-
- HY-106572A
-
|
T-1982 sodium
|
Bacterial
|
Infection
|
|
Cefbuperazone sodium is an antibacterial agent that demonstrates significant activity against bacterial infections. Cefbuperazone sodium exhibits a linear pharmacokinetic profile, allowing for effective dosage determination in clinical settings. Cefbuperazone sodium reaches peak concentrations in human plasma following intravenous infusion, indicating its rapid absorption and distribution. Cefbuperazone sodium is primarily excreted unchanged in urine, highlighting its efficiency in renal elimination.
|
-
- HY-D2194
-
|
|
Fluorescent Dye
|
Others
|
|
AgAuSe-COOH (1000 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1000 nm. AgAuSe-COOH (1000 nm) has the advantages of narrow band gap, large Stokes shift, and good photostability. AgAuSe-COOH (1000 nm) can bind proteins, antibodies, peptides, PEG, etc., and can be widely used in the field of biological imaging.
|
-
- HY-W440940
-
|
|
Liposome
|
Others
|
|
Stearic acid-PEG5000-FITC is a PEG lipid which forms micelles in water and can be used for drug delivery applications. The FITC fluorescent can be easily traced by miscroscopy. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
|
-
- HY-131885
-
|
|
GABA Receptor
|
Neurological Disease
|
|
RuBi-Glutamate hexafluorophosphate sodium is a neuronal activator. RuBi-Glutamate hexafluorophosphate sodium photocleaves to release glutamate upon one- or two-photon excitation, activating glutamate receptors in cortical pyramidal neurons. RuBi-Glutamate hexafluorophosphate sodium reduces peak amplitude of evoked GABAergic inhibitory postsynaptic currents in its caged form. RuBi-Glutamate hexafluorophosphate sodium can be used for the research of Huntington's disease .
|
-
- HY-103382R
-
|
|
Reference Standards
Fungal
|
Infection
|
|
Phenyramidol (Hydrochloride) (Standard) is the analytical standard of Phenyramidol (Hydrochloride). This product is intended for research and analytical applications. Phenyramidol hydrochloride is an anticoagulant and analgesic with activity that increases detection sensitivity in biological samples. Phenyramidol hydrochloride can be oxidized in aqueous media by electrochemical methods to achieve its quantitative analysis. The detection of Phenyramidol hydrochloride using an amino-functionalized multi-walled carbon nanotube-modified glassy carbon electrode showed significant enhancement of the current peak .
|
-
- HY-126005
-
|
|
Sodium Channel
|
Cancer
|
|
VGSC blocker-1 is a potent and small molecule blocker of neonatal isoform of the VGSC subtype, Nav1.5 (nNav1.5). VGSC blocker-1 blocks INa peak currents 34.9% at 1 μM and inhibits cell invasion 0.3% at 1 μM in human breast cancer cell line MDA-MB-231, without affecting the cell viability .
|
-
- HY-178928
-
|
|
Potassium Channel
|
Inflammation/Immunology
|
|
KV1.3-IN-3 (Compound 13a) is a KV1.3 channel inhibitor. KV1.3-IN-3 decreases the Kv1.3 peak current amplitude by more than 80%. KV1.3-IN-3 exhibits excellent pharmacological properties and safety. KV1.3-IN-3 can be used for the study of autoimmunity disease .
|
-
- HY-108588R
-
|
|
Reference Standards
Potassium Channel
|
Cardiovascular Disease
|
|
NS5806 (Standard) is the analytical standard of NS5806 (HY-108588). This product is intended for research and analytical applications. NS5806, a potent potassium current activator, increases KV4.3/KChIP2 peak current amplitudes with an EC50 of 5.3 μM. NS5806 slows KV4.3 and KV4.2 current dacay in channel complexes containing KChIP2 .
|
-
- HY-180464
-
-
- HY-D3388
-
|
|
Fluorescent Dye
Drug Derivative
|
Others
|
|
BI dihydrochloride is a DFHBI (HY-110250) derivative for imaging of RNA in cells. BI dihydrochloride increases brightness and photostability of Broccoli aptamers in cells. BI dihydrochloride enables imaging of single Broccoli-tagged mRNAs in living cells. BI dihydrochloride exhibits peak excitation of 470 nm and peak fluorescence emission of 505 nm when bound to Broccoli.
|
-
- HY-W134228
-
-
- HY-D2996
-
|
|
Fluorescent Dye
NO Synthase
|
Others
|
|
BOD-NH-SC is a dual-response fluorescent reporter molecule exhibiting activatable NIR II fluorescence, with a primary absorption peak at 664 nm. BOD-NH-SC detects the dynamic alternation of NO and H2S in living cells .
|
-
- HY-D3233
-
|
|
Fluorescent Dye
|
Others
|
|
Ctrl-BDPS1 is a BODIPY-based control probe that shows no response to copper ions (exhibiting two emission peaks at 575 nm and 708 nm; the maximum excitation wavelength is at 627 nm). Ctrl-BDPS1 has no fluorescent response to Cu + .
|
-
- HY-N14043
-
|
|
Fungal
|
Infection
|
|
Crocacin C has anti-yeast and filamentous fungal activity. Crocacin C can inhibit mouse fibroblasts L929. In the microsomes of the calf's heart, Crocacin C can interrupt the bc1 segment of electronic transmission, causes redshift of 569 nm peak in cytochrome B reduction spectrum .
|
-
- HY-N14044
-
|
|
Fungal
|
Infection
|
|
Crocacin D has anti-yeast and filamentous fungal activity. Crocacin D can inhibit mouse fibroblasts L929. In the microsomes of the calf's heart, Crocacin D can interrupt the bc1 segment of electronic transmission, causes redshift of 569 nm peak in cytochrome B reduction spectrum .
|
-
- HY-DY1106
-
|
|
Fluorescent Dye
|
Others
|
Ferrozine (solution) is a spectrophotometric reagent for iron ions, can react with divalent Fe to form a stable magenta complex species. The complex has an absorption peak at 562 nm . Ferrozine-based colorimetric assays can quantify iron in cells
Solvent and concentration: ddH2O: 10 mM
|
-
- HY-Y1816
-
-
- HY-P11734
-
|
|
Ser/Thr Protease
|
Others
|
|
Suc-AAPY-pNA is an oligptide compound and protease substrate. Suc-AAPY-pNA undergoes hydrolysis by proteases at the peptide bond between tyrosine and p-nitroaniline, releasing p-nitroaniline with an absorption peak at OD410. Suc-AAPY-pNA functions as a substrate in preclinical assays for measuring activity of acidic, neutral, and alkaline proteases .
|
-
- HY-19517
-
|
|
Endogenous Metabolite
|
Cardiovascular Disease
|
|
R1663 is a factor Xa inhibitor with anticoagulant activity. R1663 does not affect bleeding time. The pharmacodynamic effects (such as inhibition of thrombin generation) and plasma concentrations of R1663 are dose-dependent. R1663 prolongs clotting time in a concentration-dependent manner and inhibits the peak height of thrombin generation and endogenous thrombin potential .
|
-
- HY-D3448
-
|
|
Fluorescent Dye
|
Others
|
|
8-Anthracene-BODIPY 505/515-di iodine (BDP-1) is an iodine-substituted BODIPY derivative and monomer for synthesis of conjugated porous polymer CPP-1. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high (Ex/Em = 505/515 nm) .
|
-
- HY-122792R
-
|
|
Endogenous Metabolite
Reference Standards
|
Cardiovascular Disease
|
|
Phenyramidol (Hydrochloride) (Standard) is the analytical standard of Phenyramidol (Hydrochloride). This product is intended for research and analytical applications. Phenyramidol hydrochloride is an anticoagulant and analgesic with activity that increases detection sensitivity in biological samples. Phenyramidol hydrochloride can be oxidized in aqueous media by electrochemical methods to achieve its quantitative analysis. The detection of Phenyramidol hydrochloride using an amino-functionalized multi-walled carbon nanotube-modified glassy carbon electrode showed significant enhancement of the current peak .
|
-
- HY-179729
-
|
|
Glycosidase
|
Metabolic Disease
|
|
α-Glucosidase-IN-106 (Compound 17F) is an inhibitor of α-glucosidase with an IC50 of 14.9 μM. α-Glucosidase-IN-106 can effectively inhibit the peak of blood glucose after sucrose loading in normal mice, and shows a more significant anti-hyperglycemic effect in diabetic mice. α-Glucosidase-IN-106 can be used for research on diabetes .
|
-
- HY-W327027
-
|
|
Fluorescent Dye
|
Others
|
|
7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one (Compound 1) is a fluorescent probe for the detection of hydrogen sulfide (H2S). 7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one has a low detection limit (4×10 -6 mol/L), good selectivity and high sensitivity. 7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one shows almost no cytotoxicity at concentrations of 150 µg/mL. 7-(2,4-Dinitrophenoxy)-4-methyl-2H-chromen-2-one has the excitation peak of 331 nm, and the emission peak about 385 nm in DMSO solvent. Upon the addition of increasing amounts of HS -, the fluorescence intensity increases obviously at about 392 nm .
|
-
- HY-118991
-
|
|
Adenosine Receptor
|
Cardiovascular Disease
|
|
KT-1 is a vasodilator. KT 1 can decrease aortic pressure, renal blood flow, left ventricular enddiastolic pressure and resistances of total peripheral, vertebral, coronary and renal vasculatures and increase aortic blood flow, vertebral blood flow, coronary blood flow, peak positive left ventricular dP/dt and heart rate in anesthetized open-chest dogs. KT-1 can be used for the research of cardiovascular disease .
|
-
- HY-D3231
-
|
|
Fluorescent Dye
|
Others
|
|
Ratio-Coppersensor-1 is a selective ratiometric copper ion Fluorescent reporter (excitation wavelength: 480 nm; emission peak central wavelengths at 505 nm and 570 nm, respectively). Ratio-Coppersensor-1 exhibits extremely high selectivity for Cu + at cellular concentrations, outperforming other competing metal ions, and shows an approximately 20-fold change in fluorescence ratio upon Cu + binding. Ratio-Coppersensor-1 is capable of reflecting changes in Cu levels .
|
-
- HY-DY1092
-
|
Ce6 (solution)
|
Caspase
Apoptosis
Fluorescent Dye
PARP
Bcl-2 Family
|
Cancer
|
Chlorin e6 (solution) (Ce6 (solution)) is a photosensitizer and has strong absorption peaks at wavelength of 402 and 662 nm, as well as exhibiting intense fluorescence at 668 nm. Chlorin e6 has antimicrobial efficacy and anticancer activity. Chlorin e6 induces cell apoptosis via caspase-3 activation and can be used for the research of cancer .
Solvent and concentration: DMSO: 10 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
|
-
- HY-165395
-
|
|
Phosphodiesterase (PDE)
|
Inflammation/Immunology
|
|
AY 25674 is an orally active antiallergic agent and a PDE inhibitor. AY 25674 inhibits the release of allergic histamine from mast cells. AY 25674 suppresses passive anaphylaxis induced by reaginic (IgE) antibodies. AY 25674 does not inhibit the increased vascular permeability caused by non-reaginic antibodies, serotonin or histamine. AY 25674 reaches its peak activity shortly after administration; rapid tolerance occurs at high doses. AY 25674 can be used in research related to passive anaphylaxis .
|
-
- HY-W127703
-
|
|
Fluorescent Dye
Biochemical Assay Reagents
|
Others
|
|
Octadecyl Rhodamine B chloride is an amphiphilic fluorescent probe with both membrane-binding ability and fluorescent properties, which easily forms aggregates in aqueous phase leading to self-quenching. Octadecyl Rhodamine B chloride can be used for cell membrane staining and further applied in membrane biology research. The maximum absorption/emission wavelengths of Octadecyl Rhodamine B chloride monomer in Triton X-100 are 565 nm/585 nm; the absorption peaks of aggregates in water are blue-shifted to 524 nm and 574 nm, with significantly quenched fluorescence .
|
-
- HY-D0163
-
|
|
DNA Stain
|
Others
|
|
Methyl Green is a non-intercalating fluorescent labeling agent that selectively binds to the major groove of DNA. Methyl Green electrostatically interacts with the major groove of DNA through positively charged groups, exhibiting key activities such as high affinity, resistance to photobleaching, and stable fluorescence emission. Methyl Green can be directly measured by microscopy and flow cytometry, with peaks at 633 and 677 nm. Methyl Green can be used for fluorescent labeling of the nuclei of embryonic tissues or cells, or DNA staining and cell activity detection in gel electrophoresis[1][2][3].
|
-
- HY-D1106
-
|
|
Fluorescent Dye
|
Cancer
|
|
BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions . Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells .
|
-
- HY-175248
-
|
|
PSMA
|
Cancer
|
|
PSMA-DIM is a dimeric PSMA ligand with a Kd of 37.09 nM for LNCaP cells. PSMA-DIM can be radiolabeled with [ 68Ga]Ga to form [ 68Ga]Ga-PSMA-DIM. [ 68Ga]Ga-PSMA-DIM can effectively distinguish between cells and animal models with different expression levels of PSMA. [ 68Ga]Ga-PSMA-DIM exhibits high LNCaP cells uptake and tumor uptake peak values. PSMA-DIM can be used for the study of prostate cancer (PCa) .
|
-
- HY-W096983
-
|
Dodecyltrimethylammonium chloride,for IPC,≥99%
|
Environmental Pollutants
Biochemical Assay Reagents
|
Others
|
|
DTAC (Dodecyltrimethylammonium chloride), for IPC, ≥99% is a quaternary ammonium cationic surfactant. DTAC, for IPC, ≥99% can form micelles in aqueous media, which interact with and encapsulate Diclofenac sodium (HY-15037) molecules; the micellization process is entropy-driven at lower temperatures and enthalpy-driven at higher temperatures .
|
-
- HY-D0219A
-
|
|
Fluorescent Dye
|
Others
|
|
Thymol Blue sodium is an acid-base indicator used to indicate changes in pH. Thymol Blue sodium fades from red to yellow at pH 1.2 to 2.8 and from yellow to blue at pH 8.0 to 9.6. Quantitative detection is achieved through the absorption peak shift (435 nm/596 nm) of the UV-visible spectrum. Thymol blue sodium can be fixed in a silica gel matrix through sol-gel technology to form a solid-state sensor for in-situ pH measurement in the marine environment and acid-base monitoring in the biomedical field .
|
-
- HY-120131
-
|
|
Insecticide
Cholinesterase (ChE)
|
Neurological Disease
|
|
Cyanofenphos is an orally active organophosphate insecticide and brain AChE inhibitor with neurotoxicity. Cyanofenphos induces delayed neurotoxicity such as ataxia and paralysis. Cyanofenphos also causes symptoms including somnolence, reduced feed intake and weight loss in hens. Cyanofenphos has a unique self-antagonistic effect: repeated low-dose pre-treatment not only reduces subsequent acute toxicity, but also exacerbates delayed neurotoxicity and attenuates enzyme inhibition, with the protective effect peaking at 24 h after the last pre-treatment. Cyanofenphos is commonly used in studies related to delayed neurotoxicity .
|
-
- HY-D3007
-
|
|
Fluorescent Dye
|
Others
|
|
LD-CK is a fluorescent probe based on a coumarin-chromone structure, specifically designed to visualize lipid droplet polarity changes and endowed with multimodal imaging capability. LD-CK contains a high-performance lipophilic coumarin moiety, which enables it to specifically target lipid droplets upon cellular entry while minimizing background fluorescence to the greatest extent. LD-CK has an excitation wavelength (Ex) of 488 nm and an emission wavelength (Em) of 540 nm (in low-polarity environments such as toluene) or 640 nm (in high-polarity environments such as glycerol), with its emission peak undergoing a redshift as solvent polarity increases .
|
-
- HY-W800699
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 430 DBCO reacts with azides via a copper-free click chemistry reaction to form a stable triazole and does not require a Cu-catalyst or elevated temperatures. In applications where the presence of copper is a concern, BP Fluor 430 DBCO is an ideal alternative to copper requiring fluorescent alkynes.
BP Fluor 430 is a bright, photostable, green-fluorescent probe optimally excited near its absorption maximum at 432 nm. Its emission peak at 539 nm is pH independent over a wide pH range.
BP Fluor DBCO reagent is not suitable for staining intracellular components of fixed and permeabilized cells due to high backgrounds.
|
-
- HY-D1570
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPYFL C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 480/508 nm .
|
-
- HY-176065
-
|
|
Sodium Channel
|
Neurological Disease
|
|
Nav1.2-IN-1 (compound 5i), a 3-(1,2,3,6-tetrahydropyridine)-4-azaindole derivative, is a potent and selective Nav1.2 inhibitor. Nav1.2-IN-1 induces a reduction in the peak amplitude of Nav1.2 currents with an IC50 value of 7.79 μM. Nav1.2-IN-1 exhibits antiepileptic activity. Nav1.2-IN-1 shows high anticonvulsant effect and low neurotoxicity in subcutaneous Pentetrazole (sc-PTZ)-induced epilepsy mode .
|
-
- HY-W090090
-
|
Pyrromethene 546
|
Fluorescent Dye
|
Others
|
|
BODIPY493/503 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 493/503 nm .
|
-
- HY-D1237
-
|
|
Fluorescent Dye
|
Metabolic Disease
|
|
BODIPY505/515 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 505/515 nm .
|
-
- HY-138226
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY 558/568 C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 558/568 nm .
|
-
- HY-D1614
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY493/503 methyl bromide is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 493/503 nm .
|
-
- HY-162484
-
|
|
SARS-CoV
Virus Protease
|
Infection
|
|
GZNL-P36 is an orally active inhibitor for SARS-CoV-2 papain-like protease (PL pro), with an IC50 of 6.45 nM. GZNL-P36 inhibits SARS-CoV and its variants with EC50 range from 58.2 nM to 2.66 μM. GZNL-P36 exhibits a peak plasma concentration Cmax of 549 ng/mL, a half-life T1/2 of 1.45 h and a bioavailability of 74.7% in CD-1 mouse. GZNL-P36 exhibits antiviral activity in SARS-CoV-2 XXB.1 infection in mouse .
|
-
- HY-DY1004
-
|
|
Fluorescent Dye
|
Others
|
BODIPY 493/503 (solution) is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 493/503 nm.
Solvent and concentration: DMSO: 5 mM.
|
-
- HY-DY1090
-
|
|
Fluorescent Dye
|
Others
|
BODIPY 493/503 methyl bromide (solution) is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 493/503 nm .
Solvent and concentration: DMSO: 5 mM
|
-
- HY-DY1061
-
|
|
Fluorescent Dye
|
Others
|
BODIPY 558/568 C12 (solution) is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 558/568 nm .
Solvent and concentration: DMSO: 2 mM
|
-
- HY-B1247
-
|
PPIX
|
Endogenous Metabolite
|
Others
|
|
Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .
|
-
- HY-124057
-
|
|
nAChR
|
Neurological Disease
|
|
RO5126946 is a selective, orally active α7 nAChR allosteric potentiator with EC50 values of 0.06 μM (hα7 nAChR) and 770 nM (α7 nAChR), and it crosses the blood-brain barrier. RO5126946 enhances synaptic transmission and positively modulates GABA-ergic responses by increasing peak current, slowing current decay, and elevating the frequency of spontaneous inhibitory postsynaptic currents, without affecting the recovery of receptors from the desensitized state. RO5126946 not only enhances subthreshold nicotine effects and improves associative learning, but also does not interfere with the original pro-cognitive effects of nicotine. RO5126946 can be used to study cognitive impairments associated with diseases such as Alzheimer's disease and schizophrenia .
|
-
- HY-D1617
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY 500/510 C1, C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 500/510 nm . Protect from light, stored at -20°C.
|
-
- HY-D3330
-
|
|
Fluorescent Dye
|
Others
|
|
APC-Cy7 is an APC-tandem fluorochrome (allophycocyanin-cyanine 7) and degradable fluorochrome, with maximum absorption at ~650 nm, peak emission at 767 nm when excited by a 633 nm red laser, and cell-dependent degradation. APC-Cy7 undergoes time-dependent degradation (decoupling) when bound to peripheral blood leukocytes, leading to nonspecific APC channel signal, with degradation cell type-dependent. APC-Cy7 shows reduced degradation when immunolabeled cells have inhibited metabolic activity or are incubated with vitamin C. APC-Cy7 serves as a tandem fluorochrome in multiparametric flow cytometry for detection of leukocyte surface proteins when conjugated to specific antibodies (Ex/Em = 650 nm/778 nm) .
|
-
- HY-B1247A
-
|
PPIX disodium
|
Endogenous Metabolite
|
Cancer
|
|
Protoporphyrin IX disodium is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX disodium also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX disodium is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX disodium causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX disodium is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .
|
-
- HY-D0219
-
|
Thymolsulphonephthalein
|
Fluorescent Dye
|
Others
|
|
Thymol blue is a reversible pH indicator that responds to the pH of the solution through structural changes of protonation and deprotonation. Thymol blue is red (HI - form) under acidic conditions and blue (I 2- form) under alkaline conditions. Quantitative detection is achieved through the absorption peak shift (435 nm/596 nm) of the UV-visible spectrum. Thymol blue selectively responds to pH changes, changing from red to yellow at pH 1.2-2.8 and from yellow to blue at pH 8.0-9.6. Thymol blue can be fixed in a silica gel matrix through sol-gel technology to form a solid-state sensor for in-situ pH measurement in the marine environment and acid-base monitoring in the biomedical field[1][2].
|
-
- HY-113621B
-
|
|
Fluorescent Dye
MMP
|
Cancer
|
|
Ageladine A dihydrochloride is an inhibitor of matrix metalloproteinase (MMP) isolated from the marine sponge Agelas nakamurai, possessing anti-angiogenic activity. Ageladine A dihydrochloride not only inhibits MMP-2 but also MMP-1, MMP-8, MMP-9, MMP-12, and MMP-13, with IC50 values of 4.65 μM, 2.79 μM, 907.12 nM, 1.83 μM, 767.57 nM, and 1.09 μM, respectively. Additionally, Ageladine A dihydrochloride is a pH-sensitive membrane-permeable dye that emits fluorescence in the blue-green range upon UV excitation, featuring a maximum absorption peak at 370 nm. Furthermore, Ageladine A dihydrochloride serves as a reliable and stable fluorescent pH sensor for detecting changes in intracellular pH values .
|
-
- HY-B2209
-
|
Vitamin B12a
|
Endogenous Metabolite
|
Neurological Disease
Metabolic Disease
|
|
Hydroxocobalamin (Vitamin B12a) is a cyanide antidote. Hydroxocobalamin can decrease the cell and plasma cyanide concentrations and increase survival rate in acute cyanide poisoning. Hydroxocobalamin can improve newborn Cbl-C defect-induced metabolic profile and neurocognitive outcome. Hydroxocobalamin can normalize Vitamin B12 deficiency. Hydroxocobalamin can induce acute kidney injury. Hydroxocobalamin can be used for the researches of metabolic and neurological disease .
|
-
- HY-W014394R
-
|
|
TRP Channel
Reference Standards
Parasite
|
Cardiovascular Disease
|
|
Protoporphyrin IX (Standard) is the analytical standard of Protoporphyrin IX. This product is intended for research and analytical applications. Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .
|
-
- HY-B1247R
-
|
PPIX (Standard)
|
Reference Standards
Endogenous Metabolite
|
Others
|
|
Protoporphyrin IX (Standard) is the analytical standard of Protoporphyrin IX. This product is intended for research and analytical applications. Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .
|
-
- HY-12591A
-
D-Luciferin
Maximum Cited Publications
110 Publications Verification
D-(-)-Luciferin; Firefly luciferin; Beetle Luciferin
|
Fluorescent Dye
|
Others
|
|
D-luciferin is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We of er the firefly luciferase (HY-P1004A), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
|
-
- HY-12591B
-
|
D-(-)-Luciferin potassium; Firefly luciferin potassium; Beetle Luciferin potassium
|
Fluorescent Dye
|
Others
|
|
D-luciferin potassium is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We offer the firefly luciferase (HY-P1004A), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
|
-
- HY-12591
-
|
D-(-)-Luciferin sodium; Firefly luciferin sodium; Beetle Luciferin sodium
|
Fluorescent Dye
|
Others
|
|
D-luciferin sodium is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We of er the firefly luciferase (HY-P1004A), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
|
-
- HY-137055
-
|
|
Others
|
Others
|
|
PF-3774076 is a highly central nervous system (CNS) penetrant, potent, and selective human α1A-adrenoceptor partial agonist. It exhibits good potency and selectivity in multiple binding and functional assays. PF-3774076 increases peak urethral pressure in anesthetized female dogs in a dose-dependent manner via a central mechanism. PF-3774076 affects both the proximal and distal portions of the urethra in vivo. These properties suggest that PF-3774076 may have significant benefit in the treatment of stress urinary incontinence (SUI) as a CNS-penetrant α1A receptor partial agonist. However, despite its partial agonism and selectivity for α1A receptors, PF-3774076 failed to provide adequate safety differences in in vivo models of cardiovascular function. This may be due to the simultaneous activation of both peripheral and central α1A receptors. These data suggest that while central α1A partial agonists may have significant benefit in the treatment of SUI, this class of agents may have difficulty achieving the desired urethral selectivity without affecting cardiovascular function.
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-W090090
-
|
Pyrromethene 546
|
Fluorescent Dye
|
|
BODIPY493/503 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 493/503 nm .
|
-
- HY-12591B
-
|
D-(-)-Luciferin potassium; Firefly luciferin potassium; Beetle Luciferin potassium
|
Fluorescent Dye
|
|
D-luciferin potassium is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We offer the firefly luciferase (HY-P1004A), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
|
-
- HY-12591
-
|
D-(-)-Luciferin sodium; Firefly luciferin sodium; Beetle Luciferin sodium
|
Fluorescent Dye
|
|
D-luciferin sodium is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We of er the firefly luciferase (HY-P1004A), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
|
-
- HY-12591A
-
D-Luciferin
Maximum Cited Publications
110 Publications Verification
D-(-)-Luciferin; Firefly luciferin; Beetle Luciferin
|
Fluorescent Dye
|
|
D-luciferin is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We of er the firefly luciferase (HY-P1004A), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
|
-
- HY-137805
-
|
|
Fluorescent Dye
|
|
Ferrozine is a spectrophotometric reagent for iron ions, can react with divalent Fe to form a stable magenta complex species. The complex has an absorption peak at 562 nm . Ferrozine-based colorimetric assays can quantify iron in cells
|
-
- HY-111653
-
CycLuc1
2 Publications Verification
|
Fluorescent Dye
|
|
CycLuc1 is a blood-brain barrier permeable luciferase substrate that displays near-infrared (NIR) emission with a peak luminescence wavelength of 599 nm. CycLuc1 can be used for in vivo bioluminescence imaging .
|
-
- HY-D1373
-
HBC
3 Publications Verification
HBC 530
|
Fluorescent Dye
|
|
HBC (HBC 530) is a GFP fluorophore-like synthetic dye, with a structurally rigid electron acceptor and a strong electron donor. HBC has a low fluorescence background, and when combined with Pepper (RNA aptamer), HBC forms a tight complex and activates and emits bright fluorescence (Kd of ~3.5 nM). HBC emission peaks vary in different complexes and covers the spectrum from cyan to red. HBC can be used in the live cell imaging of RNA (Em/Ex = 530/485 nm) .
|
-
- HY-D1237
-
|
|
Fluorescent Dye
|
|
BODIPY505/515 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 505/515 nm .
|
-
- HY-D1106
-
|
|
Fluorescent Dye
|
|
BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions . Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells .
|
-
- HY-138226
-
|
|
Fluorescent Dye
|
|
BODIPY 558/568 C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 558/568 nm .
|
-
- HY-W127703
-
|
|
Fluorescent Dye
|
|
Octadecyl Rhodamine B chloride is an amphiphilic fluorescent probe with both membrane-binding ability and fluorescent properties, which easily forms aggregates in aqueous phase leading to self-quenching. Octadecyl Rhodamine B chloride can be used for cell membrane staining and further applied in membrane biology research. The maximum absorption/emission wavelengths of Octadecyl Rhodamine B chloride monomer in Triton X-100 are 565 nm/585 nm; the absorption peaks of aggregates in water are blue-shifted to 524 nm and 574 nm, with significantly quenched fluorescence .
|
-
- HY-DY1004
-
|
|
Fluorescent Dye
|
BODIPY 493/503 (solution) is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 493/503 nm.
Solvent and concentration: DMSO: 5 mM.
|
-
- HY-D1570
-
|
|
Fluorescent Dye
|
|
BODIPYFL C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 480/508 nm .
|
-
- HY-D1617
-
|
|
Fluorescent Dye
|
|
BODIPY 500/510 C1, C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 500/510 nm . Protect from light, stored at -20°C.
|
-
- HY-W088089
-
|
|
Fluorescent Dye
|
|
ICG-carboxylic acid is near-infrared (NIR) fluorescent probe. ICG is a fluorescent dye used in medical diagnostics. ICG has absorption peaking at 800 nm and can absorb the near IR laser energy and release heat in the dyed tissue (Ex/Em = 785/810 nm) .
|
-
- HY-D1445
-
|
|
Fluorescent Dye
|
|
PDMPO, a lysosome pH indicator, is an excellent fluorescent acidotropic reagent for fluorescence imaging. PDMPO is a potent tool with which to study acidic organelles of live cells. PDMPO exhibits pH-dependent dual-excitation and dual-emission spectral peaks. PDMPO produces a blue fluorescence in weakly acidic organelles and shifts to yellow in more acidic lysosomes. (Abs=329 nm; Em=440/540 nm) .
|
-
- HY-D0163
-
|
|
Fluorescent Dye
|
|
Methyl Green is a non-intercalating fluorescent labeling agent that selectively binds to the major groove of DNA. Methyl Green electrostatically interacts with the major groove of DNA through positively charged groups, exhibiting key activities such as high affinity, resistance to photobleaching, and stable fluorescence emission. Methyl Green can be directly measured by microscopy and flow cytometry, with peaks at 633 and 677 nm. Methyl Green can be used for fluorescent labeling of the nuclei of embryonic tissues or cells, or DNA staining and cell activity detection in gel electrophoresis[1][2][3].
|
-
- HY-D0219
-
|
Thymolsulphonephthalein
|
Fluorescent Dye
|
|
Thymol blue is a reversible pH indicator that responds to the pH of the solution through structural changes of protonation and deprotonation. Thymol blue is red (HI - form) under acidic conditions and blue (I 2- form) under alkaline conditions. Quantitative detection is achieved through the absorption peak shift (435 nm/596 nm) of the UV-visible spectrum. Thymol blue selectively responds to pH changes, changing from red to yellow at pH 1.2-2.8 and from yellow to blue at pH 8.0-9.6. Thymol blue can be fixed in a silica gel matrix through sol-gel technology to form a solid-state sensor for in-situ pH measurement in the marine environment and acid-base monitoring in the biomedical field[1][2].
|
-
- HY-137296
-
|
|
Fluorescent Dye
|
|
Lumogallion is a highly sensitive fluorescent reagent for the detection of aluminum, gallium and other metals. Lumogallion has an excitation wavelength of 490 nm and an emission spectrum in the range of 520 nm to 650 nm, with a peak near 580 nm .
|
-
- HY-D0950A
-
|
|
Fluorescent Dye
|
|
Methyl Green zinc chloride is a potent fluorescent dye. Methyl Green zinc chloride is a DNA stains of cells and electrophoretic gels. Methyl Green zinc chloride can be used as direct measuring of viability by both microscopy and flow cytometry, with peaks at 633 and 677 nm .
|
-
- HY-DY1061
-
|
|
Fluorescent Dye
|
BODIPY 558/568 C12 (solution) is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 558/568 nm .
Solvent and concentration: DMSO: 2 mM
|
-
- HY-D1950
-
|
|
Fluorescent Dye
|
|
ATTO 633 is a fluorescent dye with an absorption peak at approximately 630 nm and a fluorescence emission peak at 651 nm. ATTO 633 can be used in nanomechanical photothermal microscopy studies .
|
-
- HY-D2395
-
|
B-PE
|
Fluorescent Dye
|
|
B-Phycoerythrin (B-PE) is a light-harvesting pigment protein that can be isolated from the red alga Porphyridium cruentum. The absorption spectrum of B-Phycoerythrin peaks at 545 nm and 563 nm, with a shoulder at 498 nm .
|
-
- HY-D2083
-
|
|
Fluorescent Dye
|
|
BODIPY 540 (purity>98%) is a BODIPY dye.BODIPY dye is a small molecule dye with strong UV absorption ability.Its fluorescence peak is relatively sharp, its quantum yield is high, and it is relatively insensitive to the polarity and pH value of the environment.BODIPY 540 (purity>98%) has a purity higher than 98% and is suitable for cell experiments (Ex/Em = 540/580 nm) .
|
-
- HY-D2476
-
|
|
Fluorescent Dye
|
|
H2S Fluorescent probe 1 (Compound 2) is a fluorescent probe that detects hydrogen sulfide (H2S) with almost no cytotoxicity. Upon the addition of increasing amounts of HS - to DMSO solution of H2S Fluorescent probe 1, a new absorption peak appears gradually at 485 nm. H2S Fluorescent probe 1, the fluorescence intensity notes at 434 nm increasing rapidly by titration of HS - .
|
-
- HY-D0219A
-
|
|
Fluorescent Dye
|
|
Thymol Blue sodium is an acid-base indicator used to indicate changes in pH. Thymol Blue sodium fades from red to yellow at pH 1.2 to 2.8 and from yellow to blue at pH 8.0 to 9.6. Quantitative detection is achieved through the absorption peak shift (435 nm/596 nm) of the UV-visible spectrum. Thymol blue sodium can be fixed in a silica gel matrix through sol-gel technology to form a solid-state sensor for in-situ pH measurement in the marine environment and acid-base monitoring in the biomedical field .
|
-
- HY-D2760
-
|
|
Fluorescent Dye
|
|
BP Fluor 488 acid is a powerful labeling dye. It will react with the amine group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications.
|
-
- HY-D1489
-
|
|
Fluorescent Dye
|
|
Ethyl eosin is a fluorescent dye with an absorption peak at 527 nm and an absorption shoulder at 487 nm .
|
-
- HY-D2195
-
|
|
Fluorescent Dye
|
|
AgAuSe-PEG-NH2 (1000 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1000 nm that can be used in bioimaging.
|
-
- HY-D2198
-
|
|
Fluorescent Dye
|
|
AgAuSe-PEG-NH2 (1120 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1120 nm that can be used in bioimaging .
|
-
- HY-D1343
-
|
|
Fluorescent Dye
|
|
DMNPE-caged D-luciferin is a heterocyclic luminescent compound that is a natural ligand for luciferase, an enzyme used to detect cell activity. Its reaction requires ATP and emits yellow-green light with a peak wavelength of about 530 nm. The luciferin in the DMNPE cage easily crosses the cell membrane.
|
-
- HY-W039519
-
|
|
Fluorescent Dye
|
|
7-Methoxycoumarin-3-carboxylic acid is a fluorescent dye with an excitation peak at 355 nm and an emission peak at 405 nm. 7-Methoxycoumarin-3-carboxylic acid can be used to label peptide .
|
-
- HY-172269
-
|
|
Fluorescent Dye
|
|
BP Fluor 488 is a bright, green-fluorescent dye widely used for labeling aldehydes or ketones in polysaccharides or glycoproteins. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications.
|
-
- HY-D2338
-
|
|
Fluorescent Dye
|
|
PMBD is a lysosome (Lyso)-targeting fluorescent probe. PMBD selectively and sensitively detects endogenous N-acylethanolamine amidase (NAAA), allowing real-time visual monitoring of endogenous NAAA in living cells. PMBD has a maximum absorption peak at 350 nm. After the metabolism of NAAA, the maximum absorption peak of the product AMBD shifts red to 450 nm, and a significant fluorescence emission signal appears at 550 nm .
|
-
- HY-W800680
-
|
|
Fluorescent Dye
|
|
BP Fluor 488 DBCO is a popular labeling dye used in copper-free Click Chemistry reactions. It will react with the azide group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications. BP Fluor 488 is a pure 5-sulfonated rhodamine molecule and it eliminates the lot-to-lot variation caused by two isomers ratio differences.
|
-
- HY-D1905
-
|
|
Fluorescent Dye
|
|
ICG acid is a fluorescent dye used in medical diagnostics. ICG acid has absorption peaking at 800 nm and can absorb the near IR laser energy and release heat in the dyed tissue. ICG acid has been used in fluorescence-guided surgery to identify critical structures, including intra-abdominal tumors .
|
-
- HY-W034043
-
|
|
Fluorescent Dye
|
|
[Ir (dF (Me) ppy)2 (dtbbpy)]PF6 (Compound 3a) is a blue-green luminescent material. [Ir (dF (Me) ppy)2 (dtbbpy)]PF6 exhibits unstructured emission, with its emission peak maxima located at 498, 512 and 519 nM, respectively. [Ir (dF (Me) ppy)2 (dtbbpy)]PF6 can serve as an electrochemiluminescence-based biological probe .
|
-
- HY-D2760A
-
|
|
Fluorescent Dye
|
|
BP Fluor 488 acid triTEA is a powerful labeling dye. It will react with the amine group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications.
|
-
- HY-D0121B
-
|
|
Fluorescent Dye
|
|
INDO 1 pentasodium is a cell-impermeant ratiometric, free calcium ion (Ca 2+) fluorescent indicator that can quantitatively monitor dynamic changes in intracellular free Ca 2+ concentrations. When unbound to Ca 2+ (free state), INDO 1 pentasodium exhibits a peak emission wavelength of 485 nm under UV excitation (350 nm). Upon binding to Ca 2+ (bound state), the emission peak shifts to 405 nm. INDO 1 pentasodium is highly photolabile and susceptible to photobleaching, and its emission spectrum may overlap with the autofluorescence of NADH .
|
-
- HY-130916
-
|
5(6)-CarboxyrhodaMine 6G, succinimidyl ester
|
Fluorescent Dye
|
|
5(6)-CR6G,SE (5(6)-CarboxyrhodaMine 6G) is a trace fluorescent labeling reagent for fluorescence imaging of protein crystallization. 5(6)-CR6G,SE can efficiently bind to proteins to produce characteristic fluorescence under specific excitation conditions. 5(6)-CR6G,SE shows a peak absorption wavelength of approximately 525 nm and exhibits a peak fluorescence emission wavelength of around 550 nm when excited by a 530 nm green LED .
|
-
- HY-D2194
-
|
|
Fluorescent Dye
|
|
AgAuSe-COOH (1000 nm) is a fluorescent quantum dot that emits fluorescence in the near-infrared II region, with an emission peak reaching 1000 nm. AgAuSe-COOH (1000 nm) has the advantages of narrow band gap, large Stokes shift, and good photostability. AgAuSe-COOH (1000 nm) can bind proteins, antibodies, peptides, PEG, etc., and can be widely used in the field of biological imaging.
|
-
- HY-D3388
-
|
|
Fluorescent Dye
|
|
BI dihydrochloride is a DFHBI (HY-110250) derivative for imaging of RNA in cells. BI dihydrochloride increases brightness and photostability of Broccoli aptamers in cells. BI dihydrochloride enables imaging of single Broccoli-tagged mRNAs in living cells. BI dihydrochloride exhibits peak excitation of 470 nm and peak fluorescence emission of 505 nm when bound to Broccoli.
|
-
- HY-D2996
-
|
|
Fluorescent Dye
|
|
BOD-NH-SC is a dual-response fluorescent reporter molecule exhibiting activatable NIR II fluorescence, with a primary absorption peak at 664 nm. BOD-NH-SC detects the dynamic alternation of NO and H2S in living cells .
|
-
- HY-D3233
-
|
|
Fluorescent Dye
|
|
Ctrl-BDPS1 is a BODIPY-based control probe that shows no response to copper ions (exhibiting two emission peaks at 575 nm and 708 nm; the maximum excitation wavelength is at 627 nm). Ctrl-BDPS1 has no fluorescent response to Cu + .
|
-
- HY-DY1106
-
|
|
Fluorescent Dye
|
Ferrozine (solution) is a spectrophotometric reagent for iron ions, can react with divalent Fe to form a stable magenta complex species. The complex has an absorption peak at 562 nm . Ferrozine-based colorimetric assays can quantify iron in cells
Solvent and concentration: ddH2O: 10 mM
|
-
- HY-D3448
-
|
|
Fluorescent Dye
|
|
8-Anthracene-BODIPY 505/515-di iodine (BDP-1) is an iodine-substituted BODIPY derivative and monomer for synthesis of conjugated porous polymer CPP-1. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high (Ex/Em = 505/515 nm) .
|
-
- HY-D3231
-
|
|
Fluorescent Dye
|
|
Ratio-Coppersensor-1 is a selective ratiometric copper ion Fluorescent reporter (excitation wavelength: 480 nm; emission peak central wavelengths at 505 nm and 570 nm, respectively). Ratio-Coppersensor-1 exhibits extremely high selectivity for Cu + at cellular concentrations, outperforming other competing metal ions, and shows an approximately 20-fold change in fluorescence ratio upon Cu + binding. Ratio-Coppersensor-1 is capable of reflecting changes in Cu levels .
|
-
- HY-DY1092
-
|
Ce6 (solution)
|
Fluorescent Dye
|
Chlorin e6 (solution) (Ce6 (solution)) is a photosensitizer and has strong absorption peaks at wavelength of 402 and 662 nm, as well as exhibiting intense fluorescence at 668 nm. Chlorin e6 has antimicrobial efficacy and anticancer activity. Chlorin e6 induces cell apoptosis via caspase-3 activation and can be used for the research of cancer .
Solvent and concentration: DMSO: 10 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
|
-
- HY-D3007
-
|
|
Fluorescent Dye
|
|
LD-CK is a fluorescent probe based on a coumarin-chromone structure, specifically designed to visualize lipid droplet polarity changes and endowed with multimodal imaging capability. LD-CK contains a high-performance lipophilic coumarin moiety, which enables it to specifically target lipid droplets upon cellular entry while minimizing background fluorescence to the greatest extent. LD-CK has an excitation wavelength (Ex) of 488 nm and an emission wavelength (Em) of 540 nm (in low-polarity environments such as toluene) or 640 nm (in high-polarity environments such as glycerol), with its emission peak undergoing a redshift as solvent polarity increases .
|
-
- HY-W800699
-
|
|
Fluorescent Dye
|
|
BP Fluor 430 DBCO reacts with azides via a copper-free click chemistry reaction to form a stable triazole and does not require a Cu-catalyst or elevated temperatures. In applications where the presence of copper is a concern, BP Fluor 430 DBCO is an ideal alternative to copper requiring fluorescent alkynes.
BP Fluor 430 is a bright, photostable, green-fluorescent probe optimally excited near its absorption maximum at 432 nm. Its emission peak at 539 nm is pH independent over a wide pH range.
BP Fluor DBCO reagent is not suitable for staining intracellular components of fixed and permeabilized cells due to high backgrounds.
|
- HY-DY1090
-
|
|
Fluorescent Dye
|
BODIPY 493/503 methyl bromide (solution) is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 493/503 nm .
Solvent and concentration: DMSO: 5 mM
|
- HY-D3330
-
|
|
Fluorescent Dye
|
|
APC-Cy7 is an APC-tandem fluorochrome (allophycocyanin-cyanine 7) and degradable fluorochrome, with maximum absorption at ~650 nm, peak emission at 767 nm when excited by a 633 nm red laser, and cell-dependent degradation. APC-Cy7 undergoes time-dependent degradation (decoupling) when bound to peripheral blood leukocytes, leading to nonspecific APC channel signal, with degradation cell type-dependent. APC-Cy7 shows reduced degradation when immunolabeled cells have inhibited metabolic activity or are incubated with vitamin C. APC-Cy7 serves as a tandem fluorochrome in multiparametric flow cytometry for detection of leukocyte surface proteins when conjugated to specific antibodies (Ex/Em = 650 nm/778 nm) .
|
| Cat. No. |
Product Name |
Type |
-
- HY-W096983
-
|
Dodecyltrimethylammonium chloride,for IPC,≥99%
|
Biochemical Assay Reagents
|
|
DTAC (Dodecyltrimethylammonium chloride), for IPC, ≥99% is a quaternary ammonium cationic surfactant. DTAC, for IPC, ≥99% can form micelles in aqueous media, which interact with and encapsulate Diclofenac sodium (HY-15037) molecules; the micellization process is entropy-driven at lower temperatures and enthalpy-driven at higher temperatures .
|
-
- HY-W440915
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-FITC is a PEG lipid conjugated with fluorescein. FITC is a green dye with a peak absorption at 494 nm and a maximum emission at 520 nm, which is used for staining biological samples or nanoparticles. DSPE-PEG2000-FITC spontaneously forms lipid bilayers or micelles in water and can be used to prepare liposomes for delivering substances such as mRNA vaccines .
|
-
- HY-W440908
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-Cy3 is a PEG lipid conjugated with a fluorophore. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy and flow cytometry. The absorption wavelength of the Cy3 fluorophore peaks at 548-552 nm, while its emission wavelength reaches a maximum at 562-570 nm .
|
-
- HY-W440939
-
|
|
Biochemical Assay Reagents
|
|
Stearic acid-PEG3400-FITC is a PEG lipid which forms micelles in water and can be used for drug delivery applications. The FITC fluorescent can be easily traced by miscroscopy. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
|
-
- HY-W440938
-
|
|
Biochemical Assay Reagents
|
|
Stearic acid-PEG2000-FITC is an amphiphatic polyPEG which can self assemble to form micelles in water. The polymer can be used to encapsulate therapeutic agent. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
|
-
- HY-W440940
-
|
|
Biochemical Assay Reagents
|
|
Stearic acid-PEG5000-FITC is a PEG lipid which forms micelles in water and can be used for drug delivery applications. The FITC fluorescent can be easily traced by miscroscopy. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P4594
-
|
|
Peptides
|
Others
|
|
Z-Phe-His-Leu is the substrate of plasma converting enzyme, with enhanced discriminating power at peak converting enzyme inhibition .
|
-
- HY-P11734
-
|
|
Ser/Thr Protease
|
Others
|
|
Suc-AAPY-pNA is an oligptide compound and protease substrate. Suc-AAPY-pNA undergoes hydrolysis by proteases at the peptide bond between tyrosine and p-nitroaniline, releasing p-nitroaniline with an absorption peak at OD410. Suc-AAPY-pNA functions as a substrate in preclinical assays for measuring activity of acidic, neutral, and alkaline proteases .
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-12591A
-
D-Luciferin
Maximum Cited Publications
110 Publications Verification
D-(-)-Luciferin; Firefly luciferin; Beetle Luciferin
|
Natural Products
Animals
Other Diseases
Disease Research Fields
Source Classification
|
Fluorescent Dye
|
|
D-luciferin is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We of er the firefly luciferase (HY-P1004A), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .
|
-
-
- HY-B1247
-
-
-
- HY-N6691
-
-
-
- HY-B2209
-
-
-
- HY-B1247R
-
|
PPIX (Standard)
|
Structural Classification
Human Gut Microbiota Metabolites
Microorganisms
Ketones, Aldehydes, Acids
Endogenous metabolite
Source Classification
|
Reference Standards
Endogenous Metabolite
|
|
Protoporphyrin IX (Standard) is the analytical standard of Protoporphyrin IX. This product is intended for research and analytical applications. Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .
|
-
-
- HY-N8472
-
-
-
- HY-N6691R
-
-
-
- HY-N6720
-
-
-
- HY-N14038
-
|
|
Natural Products
Microorganisms
Source Classification
|
Fungal
|
|
Crocacin A has anti-yeast and filamentous fungal activity. Crocacin A can inhibit mouse fibroblasts L929. In the microsomes of the calf's heart, Crocacin A can interrupt the bc1 segment of electronic transmission, causes redshift of 569 nm peak in cytochrome B reduction spectrum .
|
-
-
- HY-N14040
-
|
|
Natural Products
Microorganisms
Source Classification
|
Fungal
|
|
Crocacin B has anti-yeast and filamentous fungal activity. Crocacin B can inhibit mouse fibroblasts L929. In the microsomes of the calf's heart, Crocacin B can interrupt the bc1 segment of electronic transmission, causes redshift of 569 nm peak in cytochrome B reduction spectrum .
|
-
-
- HY-103382R
-
|
|
Alkaloids
Microorganisms
Indole Alkaloids
Source Classification
|
Reference Standards
Fungal
|
|
Phenyramidol (Hydrochloride) (Standard) is the analytical standard of Phenyramidol (Hydrochloride). This product is intended for research and analytical applications. Phenyramidol hydrochloride is an anticoagulant and analgesic with activity that increases detection sensitivity in biological samples. Phenyramidol hydrochloride can be oxidized in aqueous media by electrochemical methods to achieve its quantitative analysis. The detection of Phenyramidol hydrochloride using an amino-functionalized multi-walled carbon nanotube-modified glassy carbon electrode showed significant enhancement of the current peak .
|
-
-
- HY-W014394R
-
|
|
Structural Classification
Monophenols
other families
Phenols
Plants
Source Classification
|
TRP Channel
Reference Standards
Parasite
|
|
Protoporphyrin IX (Standard) is the analytical standard of Protoporphyrin IX. This product is intended for research and analytical applications. Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma .
|
-
-
- HY-N14043
-
|
|
Natural Products
Microorganisms
Source Classification
|
Fungal
|
|
Crocacin C has anti-yeast and filamentous fungal activity. Crocacin C can inhibit mouse fibroblasts L929. In the microsomes of the calf's heart, Crocacin C can interrupt the bc1 segment of electronic transmission, causes redshift of 569 nm peak in cytochrome B reduction spectrum .
|
-
-
- HY-N14044
-
|
|
Natural Products
Microorganisms
Source Classification
|
Fungal
|
|
Crocacin D has anti-yeast and filamentous fungal activity. Crocacin D can inhibit mouse fibroblasts L929. In the microsomes of the calf's heart, Crocacin D can interrupt the bc1 segment of electronic transmission, causes redshift of 569 nm peak in cytochrome B reduction spectrum .
|
-
| Recombinant Proteins Recommended: |
|
| Cat. No. |
Compare |
Product Name |
Species |
Source |
Image |
Compare Products
|
| Products |
|
| Cat. No. |
|
| Species |
|
| Source |
|
| Tag |
|
| Accession |
|
| Gene ID |
|
| Molecular Weight |
|
| Purity |
|
| Endotoxin Level |
|
| Biological Activity |
|
| Appearance |
|
| Formulation |
|
| Storage & Stability |
|
| Shipping |
|
| Free Sample |
Yes
No
|
| Size |
* This product has been "discontinued".
Optimized version of product available:
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-W440915
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DSPE-PEG2000-FITC is a PEG lipid conjugated with fluorescein. FITC is a green dye with a peak absorption at 494 nm and a maximum emission at 520 nm, which is used for staining biological samples or nanoparticles. DSPE-PEG2000-FITC spontaneously forms lipid bilayers or micelles in water and can be used to prepare liposomes for delivering substances such as mRNA vaccines .
|
-
- HY-W440908
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
DSPE-PEG2000-Cy3 is a PEG lipid conjugated with a fluorophore. The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy and flow cytometry. The absorption wavelength of the Cy3 fluorophore peaks at 548-552 nm, while its emission wavelength reaches a maximum at 562-570 nm .
|
-
- HY-W440939
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
Stearic acid-PEG3400-FITC is a PEG lipid which forms micelles in water and can be used for drug delivery applications. The FITC fluorescent can be easily traced by miscroscopy. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
|
-
- HY-174486
-
|
|
|
mRNA
Reporter Genes
|
|
mCherry mRNA (5moU) encodes the fluorescent protein, mCherry, which is derived from DsRed, a protein found in Discosoma sp. mCherry is a monomeric fluorophore with a peak absorption at 587 nm and emission at 610 nm. It is stable and resistant to photobleaching.
|
-
- HY-RS10311
-
|
|
|
siRNAs
Human Pre-designed siRNA Sets
|
|
PEAK3 Human Pre-designed siRNA Set A contains three designed siRNAs for PEAK3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
|
-
- HY-RS10310
-
|
|
|
siRNAs
Human Pre-designed siRNA Sets
|
|
PEAK1 Human Pre-designed siRNA Set A contains three designed siRNAs for PEAK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
|
-
- HY-W440938
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
Stearic acid-PEG2000-FITC is an amphiphatic polyPEG which can self assemble to form micelles in water. The polymer can be used to encapsulate therapeutic agent. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
|
-
- HY-W440940
-
|
|
|
Pegylated Lipids
Fluorescent Lipids
|
|
Stearic acid-PEG5000-FITC is a PEG lipid which forms micelles in water and can be used for drug delivery applications. The FITC fluorescent can be easily traced by miscroscopy. FITC is a green dye with peak absorption at 494 nm and maximum emission at 520 nm and can be used for staining biological samples or nanoparticles. FITC can be easily traced by fluorescence microscopy.
|
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent:
![[Ir(dF(Me)ppy)2(dtbbpy)]PF6](http://file.medchemexpress.com/product_pic/hy-w034043.gif)
