69898-45-9
Chemical Structure
Ferrozine
- CAS No.: 69898-45-9
- Formula:C20H13N4NaO6S2
- Molecular Weight:492.46
IUPAC Name: sodium 4-(3-(pyridin-2-yl)-5-(4-sulfophenyl)-1,2,4-triazin-6-yl)benzenesulfonate
InChIKey: ZGVNYCXXBQPDPQ-UHFFFAOYSA-M
SMILES: O=S(C1=CC=C(C2=NC(C3=NC=CC=C3)=NN=C2C4=CC=C(S(=O)(O[Na])=O)C=C4)C=C1)(O)=O
Biological Activity: Ferrozine is a spectrophotometric reagent for iron ions, can react with divalent Fe to form a stable magenta complex species. The complex has an absorption peak at 562 nm[1][2]. Ferrozine-based colorimetric assays can quantify iron in cells[3]
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ferrozine | 99.96% | Ferrozine is a spectrophotometric reagent for iron ions, can react with divalent Fe to form a stable magenta complex species. The complex has an absorption peak at 562 nm. Ferrozine-based colorimetric assays can quantify iron in cells | ||||||||||||||||||||
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Ferrozine (solution) | Ferrozine (solution) is a spectrophotometric reagent for iron ions, can react with divalent Fe to form a stable magenta complex species. The complex has an absorption peak at 562 nm. Ferrozine-based colorimetric assays can quantify iron in cells Solvent and concentration: ddH2O: 10 mM |
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SB 203580 sulfone | 99.25% | SB 203580 sulfone is an analog of p38 MAP kinase inhibitor SB 203580. SB 203580 sulfone inhibits the IL-1 production (IC50 of 0.2 μM in monocytes) and binds competitively with CSAID binding proteins (CSBP), inhibits it mediated stress response signaling with an IC50 of 0.03 μM. SB 203580 sulfone inhibits 5-LO with an IC50 value of 24 µM. SB 203580 sulfone can be used in the research of inflammatory diseases. | ||||||||||||||||||||
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ML228 | 98.0% | ML228 (CID-46742353) is a potent the Hypoxia Inducible Factor (HIF) pathway activator with EC50 of 1 μM. ML228 potently activates HIF in vitro as well as its downstream target VEGF. | ||||||||||||||||||||
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GPR84 antagonist 1 | 98.56% | GPR84 antagonist 1 is a high affinity and highly selective competitive antagonist of human GPR84. | ||||||||||||||||||||
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ML228 analog | 98.02% | ML228 analog is an analog of ML228 (HY-12754). ML228 is a potent activator of HIF. | ||||||||||||||||||||
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Ferene disodium | 99.94% | Ferene disodium (Ferene S) is a chromogenic chelating agent used primarily as a specific detection reagent for Fe2+ and iron-binding proteins. Ferene disodium specifically recognizes iron ions by binding to Fe2+ to form a stable 3:1 chromogenic complex. Ferene disodium is used for the colorimetric quantitative determination of serum iron and lactoferrin. | ||||||||||||||||||||
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Ferrotrace | ≥99.0% | Ferrotrace (Compound dppt) is a ligand. Ferrotrace can bind to DNA and BSA (Kb = 0.14 x 104 M-1). Ferrotrace shows an IC50 of 17.35 μM for MCF-7 cells. Ferrotrace can be used for the research of breast cancer. | ||||||||||||||||||||
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4-(4-Sulfophenyl)benzenesulfonic acid | 99.15% | 4-(4-Sulfophenyl)benzenesulfonic acid (Biphenyl-4,4'-disulphonic acid) is a metal-organic framework (MOF). | ||||||||||||||||||||
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4-([2,2':6',2''-Terpyridin]-4'-yl)benzene-1,3-disulfonic acid | 4-([2,2':6',2''-Terpyridin]-4'-yl)benzene-1,3-disulfonic acid is a metal-organic framework (MOF). | |||||||||||||||||||||
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5'-(4-Sulfophenyl)-[1,1':3',1''-terphenyl]-4,4''-disulfonic acid | 5'-(4-Sulfophenyl)-[1,1':3',1''-terphenyl]-4,4''-disulfonic acid is a metal-organic framework (MOF). | |||||||||||||||||||||
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Disodium 6,6′-oxybis(2-naphthalenesulfonate) | Disodium 6,6′-oxybis(2-naphthalenesulfonate) is an impurity of Sunset Yellow FCF (HY-D0249). Disodium 6,6′-oxybis(2-naphthalenesulfonate) acts as a surfactant, emulsifier, and dispersant. The compound has found applications in synthesizing polymers, pharmaceuticals, and agrochemicals. | |||||||||||||||||||||
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References
- [1]. Ferrozine-A New Spectrophotometric Reagent for Iron. ANALYTICAL CHEMISTRY, VOL. 42, NO. 7, JUNE 1970. 779-781
- [2]. E Viollier, et al. The ferrozine method revisited: Fe(II)/Fe(III) determination in natural waters.
- [3]. Riemer et al.Colorimetric ferrozine-based assay for the quantitation of iron in cultured cells. Anal Biochem. 2004 Aug 15;331(2):370-5. [Content Brief]