GPR84 antagonist 1

Cat. No.: HY-139675 Purity: 99.21%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

GPR84 antagonist 1 is a high affinity and highly selective competitive antagonist of human GPR84.

For research use only. We do not sell to patients.

GPR84 antagonist 1 Chemical Structure

CAS No. : 2762180-28-7

Size	Price	Stock	Quantity
Solid + Solvent
10 mM * 1 mL in DMSO ready for reconstitution	USD 605	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 605	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	USD 550	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 890	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

GPR84 antagonist 1 is a high affinity and highly selective competitive antagonist of human GPR84.

Molecular Weight

422.48

Formula

C₂₆H₂₂N₄O₂

CAS No.

2762180-28-7

Appearance

Solid

Color

Off-white to light yellow

SMILES

COC1=CC=C(C2=C(C3=CC=C(OC)C=C3)N=C(CC4=CNC5=C4C=CC=C5)N=N2)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (118.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.3670 mL	11.8349 mL	23.6698 mL
5 mM	0.4734 mL	2.3670 mL	4.7340 mL
10 mM	0.2367 mL	1.1835 mL	2.3670 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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mg/kg

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.21%

Select Batch:

Data Sheet (272 KB) SDS (251 KB)

COA (255 KB) HNMR (114 KB) RP-HPLC (357 KB) MS (105 KB)

Handling Instructions (2659 KB)

References

[1]. Jenkins L, et al. Discovery and Characterization of Novel Antagonists of the Proinflammatory Orphan Receptor GPR84. ACS Pharmacol Transl Sci. 2021 Sep 7;4(5):1598-1613. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.3670 mL	11.8349 mL	23.6698 mL	59.1744 mL
	5 mM	0.4734 mL	2.3670 mL	4.7340 mL	11.8349 mL
	10 mM	0.2367 mL	1.1835 mL	2.3670 mL	5.9174 mL
	15 mM	0.1578 mL	0.7890 mL	1.5780 mL	3.9450 mL
	20 mM	0.1183 mL	0.5917 mL	1.1835 mL	2.9587 mL
	25 mM	0.0947 mL	0.4734 mL	0.9468 mL	2.3670 mL
	30 mM	0.0789 mL	0.3945 mL	0.7890 mL	1.9725 mL
	40 mM	0.0592 mL	0.2959 mL	0.5917 mL	1.4794 mL
	50 mM	0.0473 mL	0.2367 mL	0.4734 mL	1.1835 mL
	60 mM	0.0394 mL	0.1972 mL	0.3945 mL	0.9862 mL
	80 mM	0.0296 mL	0.1479 mL	0.2959 mL	0.7397 mL
	100 mM	0.0237 mL	0.1183 mL	0.2367 mL	0.5917 mL