1 Result for "

primary murine bone marrow cells

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "primary murine bone marrow cells" in MCE Product Catalog:

Cat. No.: HY-P2612
CAS No.: 199999-60-5
Research Areas:  

Inflammation/Immunology

WP9QY is an inhibitor targeting TNFα and RANKL, which blocks the TNFα-TNFR1 interaction and inhibits TNFα-mediated apoptosis, cytotoxicity and bone destruction. WP9QY inhibits osteoclastogenesis and promotes osteoblast differentiation, induces chondrocyte proliferation and glycosaminoglycan production, and synergizes with TGF-β3 to promote chondrogenesis. WP9QY effectively repairs full-thickness articular cartilage defects in rabbits via intra-articular injection, and inhibits methylmercury-induced reduction of NeuN-positive cells in mouse brain slices. WP9QY can be applied to the research of diseases related to methylmercury-induced neuronal death, cartilage injury, osteoarthritis and bone loss .
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