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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
16 Results for "
prolyl 4-hydroxylase
" in MedChemExpress (MCE) Product Catalog:
Products (16)
16 Results for "prolyl 4-hydroxylase" in MCE Product Catalog:
4
4 Cited Publications
Diethyl-pythiDC is an inhibitor of collagen prolyl 4-hydroxylases (CP4Hs).
1
1 Cited Publications
Target:
Research Areas:
1,4-DPCA, a potent prolyl-4-hydroxylase inhibitor, is a collagen hydroxylation inhibitor in human foreskin fibroblasts with an IC50 of 2.4 µM. 1,4-DPCA inhibits prolyl-4-hydroxylases α isoforms stabilizes HIF-1α protein. 1,4-DPCA also inhibits factor inhibiting HIF (FIH) with an IC50 of 60 μM .
1
1 Cited Publications
Cat. No.: HY-N2589
CAS No.: 19416-87-6
Category:
Vaccaria segetalis (Neck.) Garcke Flavonoids Flavones Other Diseases Phenols Polyphenols Plants Disease Research Fields Caryophyllaceae
Target:
1
1 Cited Publications
Cat. No.: HY-P71917
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: P4HB; Protein Disulfide Isomerase Family A, Member 1; Prev. ERBA2L; Cellular Thyroid Hormone-Binding Protein; Prev. PO4DB; prolyl 4-hydroxylase, Beta Polypeptide; PDIA1; Collagen prolyl 4-hydroxylase Beta; PDI; Procollagen-Proline, 2-Oxoglutarate 4-Dioxyg
Species:
Human
Source:
E. coli
Target:
Research Areas:
PythiDC is a selective collagen prolyl 4-hydroxylase (CP4H1) inhibitor with an IC50 value of 4.0 μM. PythiDC can be used as a CP4H probe and also can be used for the development of a new class of antifibrotic and antimetastatic agents .
Cat. No.: HY-W025062
CAS No.: 41438-38-4
Target:
Research Areas:
Diethyl pyridine-2,4-dicarb is a potent prolyl 4-hydroxylase-directed proinhibitor. Diethyl pyridine-2,4-dicarb inhibits prolyl hydroxylation and procollagen processing in chick-embryo calvaria .
Cat. No.: HY-106894
CAS No.: 128075-79-6
Synonyms: HOE 077
Target:
Research Areas:
Lufironil (HOE 077) is a prolyl 4-hydroxylase inhibitor. Lufironil is developed for the research of chronic liver diseases including alcoholic hepatitis and liver cirrhosis .
Cat. No.: HY-122483
CAS No.: 1821370-64-2
Target:
Research Areas:
iethyl pyimDC is a collagen prolyl 4-hydroxylase (CP4H1) inhibitor inhibitor with the IC50 of 2.6μM. Diethyl pyimDC can be used for study of antifibrotic and antimetastatic .
Cat. No.: HY-P71087
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: P4HB; Protein Disulfide Isomerase Family A, Member 1; Prev. ERBA2L; Cellular Thyroid Hormone-Binding Protein; Prev. PO4DB; prolyl 4-hydroxylase, Beta Polypeptide; PDIA1; Collagen prolyl 4-hydroxylase Beta; PDI; Procollagen-Proline, 2-Oxoglutarate 4-Dioxyg
Species:
Human
Source:
HEK293
Cat. No.: HY-P74658
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: P4HB; Protein Disulfide Isomerase Family A, Member 1; Prev. ERBA2L; Cellular Thyroid Hormone-Binding Protein; Prev. PO4DB; prolyl 4-hydroxylase, Beta Polypeptide; PDIA1; Collagen prolyl 4-hydroxylase Beta; PDI; Procollagen-Proline, 2-Oxoglutarate 4-Dioxyg
Species:
Mouse
Source:
HEK293
Cat. No.: HY-123004
CAS No.: 143199-54-6
Target:
Research Areas:
S 4404 is a prolyl-4-hydroxylase inhibitor. S 4404 functions as a non-substrate of hepatobiliary transport systems. S 4404 undergoes metabolic breakdown into fluorescent and red-colored metabolites. S 4404 can be used for the research of liver fibrosis .
Cat. No.: HY-103068R
CAS No.: 1821370-70-0
Target:
Research Areas:
Diethyl-pythiDC (Standard) is the analytical standard of Diethyl-pythiDC (HY-103068). This product is intended for research and analytical applications. Diethyl-pythiDC is an inhibitor of collagen prolyl 4-hydroxylases (CP4Hs).
Cat. No.: HY-W1059094
CAS No.: 5998-89-0
Target:
Research Areas:
2-(Pyridin-2-yl) oxazole is a bis-heteroaryl compound that serves as a pharmaceutical intermediate for synthesizing active compounds, such as CP4H1 inhibitors .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
