PythiDC
Based on 1 Customer Validation
PythiDC is a selective collagen prolyl 4-hydroxylase (CP4H1) inhibitor with an IC50 value of 4.0 μM. PythiDC can be used as a CP4H probe and also can be used for the development of a new class of antifibrotic and antimetastatic agents.
For research use only. We do not sell to patients.
- Purity: 99.05%
- CAS No.: 1821370-71-1
- Formula: C10H6N2O4S
- Molecular Weight:250.23
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 1821370-71-1
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Appearance Solid
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Molecular Weight 250.23
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Formula C10H6N2O4S
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Color White to off-white
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SMILES
O=C(C1=CC=C(C2=NC=C(C(O)=O)S2)N=C1)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
1 M NaOH : 50 mg/mL (199.82 mM; Need ultrasonic)
DMSO : 4.9 mg/mL (19.58 mM; ultrasonic and warming and adjust pH to 4 with HCl and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / 1 M NaOH | 1 mM | 3.9963 mL | 19.9816 mL | 39.9632 mL | 99.9081 mL |
| 5 mM | 0.7993 mL | 3.9963 mL | 7.9926 mL | 19.9816 mL | |
| 10 mM | 0.3996 mL | 1.9982 mL | 3.9963 mL | 9.9908 mL | |
| 15 mM | 0.2664 mL | 1.3321 mL | 2.6642 mL | 6.6605 mL | |
| 1 M NaOH | 20 mM | 0.1998 mL | 0.9991 mL | 1.9982 mL | 4.9954 mL |
| 25 mM | 0.1599 mL | 0.7993 mL | 1.5985 mL | 3.9963 mL | |
| 30 mM | 0.1332 mL | 0.6661 mL | 1.3321 mL | 3.3303 mL | |
| 40 mM | 0.0999 mL | 0.4995 mL | 0.9991 mL | 2.4977 mL | |
| 50 mM | 0.0799 mL | 0.3996 mL | 0.7993 mL | 1.9982 mL | |
| 60 mM | 0.0666 mL | 0.3330 mL | 0.6661 mL | 1.6651 mL | |
| 80 mM | 0.0500 mL | 0.2498 mL | 0.4995 mL | 1.2489 mL | |
| 100 mM | 0.0400 mL | 0.1998 mL | 0.3996 mL | 0.9991 mL |